The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
STITCH 2: an interaction network database for small molecules and proteins
Open accessAbstract
Over the last years, the publicly available knowledge on interactions between small molecules and proteins has been steadily increasing. To create a network of interactions, STITCH aims to integrate the data dispersed over the literature and various databases of biological pathways, drug-target relationships and binding affinities. In STITCH 2, the number of relevant interactions is increased by incorporation of BindingDB, PharmGKB and the Comparative Toxicogenomics Database. The resulting network can be explored interactively or used as the basis for large-scale analyses. To facilitate links to other chemical databases, we adopt InChIKeys that allow identification of chemicals with a short, checksum-like string. STITCH 2.0 connects proteins from 630 organisms to over 74,000 different chemicals, including 2200 drugs. STITCH can be accessed at http://stitch.embl.de/.
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Citations
Cites
DrugBank: a comprehensive resource for in silico drug discovery and exploration
Wishart, D. S. (2006) · Nucleic Acids Research · doi:10.1093/nar/gkj067 · Cited by 3,892
Database resources of the National Center for Biotechnology Information
Wheeler, D. L., Barrett, T., Benson, D. A., Bryant, S. H., Canese, K., Chetvernin, V., Church, D. M., DiCuccio, M., Edgar, R., Federhen, S., et al. (2007) · Nucleic Acids Research · doi:10.1093/nar/gkl1031 · Cited by 734
SuperTarget and Matador: resources for exploring drug-target relationships
Gunther, S., Kuhn, M., Dunkel, M., Campillos, M., Senger, C., Petsalaki, E., Ahmed, J., Urdiales, E. G., Gewiess, A., Jensen, L. J., et al. (2007) · Nucleic Acids Research · doi:10.1093/nar/gkm862 · Cited by 647
Self-citation
Cited by
Fourches, D., Muratov, E., & Tropsha, A. (2010) · Journal of Chemical Information and Modeling · doi:10.1021/ci100176x · Cited by 832
ProtChemSI: a network of protein-chemical structural interactions
Kalinina, O. V., Wichmann, O., Apic, G., & Russell, R. B. (2012) · Nucleic Acids Research · doi:10.1093/nar/gkr1049 · Cited by 14
Metadata
- Authors
- Kuhn, M., Szklarczyk, D., Franceschini, A., Campillos, M., von Mering, C., Jensen, L. J., Beyer, A., & Bork, P.
- Venue
- Nucleic Acids Research
- Publisher
- Oxford University Press (OUP)
- Published
- 2009-11-06
- Volume
- 38
- Issue
- suppl_1
- Pages
- D552-D556
- ISSN
- 0305-1048 (ISSN-L)
- 1362-4962
- OpenAlex
- W2007287574
- Cited by
- 276
- References
- 3
- FWCI
- 9.84
- Type
- journal article
- Language
- en
- Open access
- gold
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- Kuhn, M., Szklarczyk, D., Franceschini, A., Campillos, M., von Mering, C., Jensen, L. J., Beyer, A., & Bork, P. (2010). STITCH 2: an interaction network database for small molecules and proteins. Nucleic Acids Research. https://doi.org/10.1093/nar/gkp937
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