The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
The ChEBI reference database and ontology for biologically relevant chemistry: enhancements for 2013
Open accessAbstract
ChEBI (http://www.ebi.ac.uk/chebi) is a database and ontology of chemical entities of biological interest. Over the past few years, ChEBI has continued to grow steadily in content, and has added several new features. In addition to incorporating all user-requested compounds, our annotation efforts have emphasized immunology, natural products and metabolites in many species. All database entries are now 'is_a' classified within the ontology, meaning that all of the chemicals are available to semantic reasoning tools that harness the classification hierarchy. We have completely aligned the ontology with the Open Biomedical Ontologies (OBO) Foundry-recommended upper level Basic Formal Ontology. Furthermore, we have aligned our chemical classification with the classification of chemical-involving processes in the Gene Ontology (GO), and as a result of this effort, the majority of chemical-involving processes in GO are now defined in terms of the ChEBI entities that participate in them. This effort necessitated incorporating many additional biologically relevant compounds. We have incorporated additional data types including reference citations, and the species and component for metabolites. Finally, our website and web services have had several enhancements, most notably the provision of a dynamic new interactive graph-based ontology visualization.
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“Furthermore, recognized semantic terms are required if such models are to be used in computational pipelines, allowing for the automation of the systems biology life cycle, from model generation, through to integration with experimental omics data, and simulation (17).”
BackgroundSelf-citation
Research works printed but not linked: 23
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Cited by
UniProt: a hub for protein information
The UniProt Consortium (2015) · Nucleic Acids Research · doi:10.1093/nar/gku989 · Cited by 5,106
Gene Ontology Consortium: going forward
The Gene Ontology Consortium (2015) · Nucleic Acids Research · doi:10.1093/nar/gku1179 · Cited by 3,492
Caspi, R., Billington, R., Ferrer, L., Foerster, H., Fulcher, C. A., Keseler, I. M., Kothari, A., Krummenacker, M., Latendresse, M., Mueller, L. A., et al. (2016) · Nucleic Acids Research · doi:10.1093/nar/gkv1164 · Cited by 3,395
The Reactome pathway knowledgebase
Croft, D., Mundo, A. F., Haw, R., Milacic, M., Weiser, J., Wu, G., Caudy, M., Garapati, P., Gillespie, M., Kamdar, M. R., et al. (2014) · Nucleic Acids Research · doi:10.1093/nar/gkt1102 · Cited by 1,889
Self-citationSearching molecular structure databases with tandem mass spectra using CSI:FingerID
Dührkop, K., Shen, H., Meusel, M., Rousu, J., & Böcker, S. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1509788112 · Cited by 1,190
Metadata
- Authors
- Hastings, J., de Matos, P., Dekker, A., Ennis, M., Harsha, B., Kale, N., Muthukrishnan, V., Owen, G., Turner, S., Williams, M., & Steinbeck, C.
- Venue
- Nucleic Acids Research
- Publisher
- Oxford University Press (OUP)
- Published
- 2012-11-23
- Volume
- 41
- Issue
- D1
- Pages
- D456-D463
- ISSN
- 0305-1048 (ISSN-L)
- 1362-4962
- OpenAlex
- W2140611297
- Cited by
- 591
- References
- 4
- FWCI
- 20.21
- Type
- journal article
- Language
- en
- Open access
- gold
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- Hastings, J., de Matos, P., Dekker, A., Ennis, M., Harsha, B., Kale, N., Muthukrishnan, V., Owen, G., Turner, S., Williams, M., & Steinbeck, C. (2012). The ChEBI reference database and ontology for biologically relevant chemistry: enhancements for 2013. Nucleic Acids Research. https://doi.org/10.1093/nar/gks1146
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