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Toward the identification and regulation of the Arabidopsis thaliana ABI3 regulon

Open access
Mönke, Gudrun, Seifert, Michael, Keilwagen, Jens, Mohr, Michaela, Grosse, Ivo, Hähnel, Urs, Junker, Astrid, Weisshaar, Bernd, Conrad, Udo, Bäumlein, Helmut, Altschmied, Lothar·2012·Nucleic Acids Research

Abstract

The plant-specific, B3 domain-containing transcription factor ABSCISIC ACID INSENSITIVE3 (ABI3) is an essential component of the regulatory network controlling the development and maturation of the Arabidopsis thaliana seed. Genome-wide chromatin immunoprecipitation (ChIP-chip), transcriptome analysis, quantitative reverse transcriptase-polymerase chain reaction and a transient promoter activation assay have been combined to identify a set of 98 ABI3 target genes. Most of these presumptive ABI3 targets require the presence of abscisic acid for their activation and are specifically expressed during seed maturation. ABI3 target promoters are enriched for G-box-like and RY-like elements. The general occurrence of these cis motifs in non-ABI3 target promoters suggests the existence of as yet unidentified regulatory signals, some of which may be associated with epigenetic control. Several members of the ABI3 regulon are also regulated by other transcription factors, including the seed-specific, B3 domain-containing FUS3 and LEC2. The data strengthen and extend the notion that ABI3 is essential for the protection of embryonic structures from desiccation and raise pertinent questions regarding the specificity of promoter recognition.

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Metadata

Authors
Mönke, G., Seifert, M., Keilwagen, J., Mohr, M., Grosse, I., Hähnel, U., Junker, A., Weisshaar, B., Conrad, U., Bäumlein, H., & Altschmied, L.
Venue
Nucleic Acids Research
Published
2012-06-21
Volume
40
Issue
17
Pages
8240-8254
ISSN
  • 0305-1048 (ISSN-L)
  • 1362-4962
OpenAlex
W2072453401
Cited by
177
References
2
FWCI
16.34
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: Toward the identification and regulation of the Arabidopsis thaliana ABI3 regulon. https://app.cochat.ai/papers/10.1093/nar/gks594
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Mönke, G., Seifert, M., Keilwagen, J., Mohr, M., Grosse, I., Hähnel, U., Junker, A., Weisshaar, B., Conrad, U., Bäumlein, H., & Altschmied, L. (2012). Toward the identification and regulation of the Arabidopsis thaliana ABI3 regulon. Nucleic Acids Research. https://doi.org/10.1093/nar/gks594

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