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Cited by 983

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JASPAR 2014: an extensively expanded and updated open-access database of transcription factor binding profiles

Open access
Mathelier, Anthony, Zhao, Xiaobei, Zhang, Allen W., Parcy, François, Worsley-Hunt, Rebecca, Arenillas, David J., Buchman, Sorana, Chen, Chih-yu, Chou, Alice, Ienasescu, Hans, Lim, Jonathan, Shyr, Casper, Tan, Ge, Zhou, Michelle, Lenhard, Boris, Sandelin, Albin, Wasserman, Wyeth W.·2014·Nucleic Acids Research

Abstract

JASPAR (http://jaspar.genereg.net) is the largest open-access database of matrix-based nucleotide profiles describing the binding preference of transcription factors from multiple species. The fifth major release greatly expands the heart of JASPAR-the JASPAR CORE subcollection, which contains curated, non-redundant profiles-with 135 new curated profiles (74 in vertebrates, 8 in Drosophila melanogaster, 10 in Caenorhabditis elegans and 43 in Arabidopsis thaliana; a 30% increase in total) and 43 older updated profiles (36 in vertebrates, 3 in D. melanogaster and 4 in A. thaliana; a 9% update in total). The new and updated profiles are mainly derived from published chromatin immunoprecipitation-seq experimental datasets. In addition, the web interface has been enhanced with advanced capabilities in browsing, searching and subsetting. Finally, the new JASPAR release is accompanied by a new BioPython package, a new R tool package and a new R/Bioconductor data package to facilitate access for both manual and automated methods.

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Metadata

Authors
Mathelier, A., Zhao, X., Zhang, A. W., Parcy, F., Worsley-Hunt, R., Arenillas, D. J., Buchman, S., Chen, C.-Y., Chou, A., Ienasescu, H., Lim, J., Shyr, C., Tan, G., Zhou, M., Lenhard, B., Sandelin, A., & Wasserman, W. W.
Venue
Nucleic Acids Research
Published
2013-11-04
Volume
42
Issue
D1
Pages
D142-D147
ISSN
  • 0305-1048 (ISSN-L)
  • 1362-4962
OpenAlex
W1964733653
Cited by
983
References
5
FWCI
67.51
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: JASPAR 2014: an extensively expanded and updated open-access database of transcription factor binding profiles. https://app.cochat.ai/papers/10.1093/nar/gkt997
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Mathelier, A., Zhao, X., Zhang, A. W., Parcy, F., Worsley-Hunt, R., Arenillas, D. J., Buchman, S., Chen, C.-Y., Chou, A., Ienasescu, H., Lim, J., Shyr, C., Tan, G., Zhou, M., Lenhard, B., Sandelin, A., & Wasserman, W. W. (2014). JASPAR 2014: an extensively expanded and updated open-access database of transcription factor binding profiles. Nucleic Acids Research. https://doi.org/10.1093/nar/gkt997

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