The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
PANNZER2: a rapid functional annotation web server
Open accessAbstract
The unprecedented growth of high-throughput sequencing has led to an ever-widening annotation gap in protein databases. While computational prediction methods are available to make up the shortfall, a majority of public web servers are hindered by practical limitations and poor performance. Here, we introduce PANNZER2 (Protein ANNotation with Z-scoRE), a fast functional annotation web server that provides both Gene Ontology (GO) annotations and free text description predictions. PANNZER2 uses SANSparallel to perform high-performance homology searches, making bulk annotation based on sequence similarity practical. PANNZER2 can output GO annotations from multiple scoring functions, enabling users to see which predictions are robust across predictors. Finally, PANNZER2 predictions scored within the top 10 methods for molecular function and biological process in the CAFA2 NK-full benchmark. The PANNZER2 web server is updated on a monthly schedule and is accessible at http://ekhidna2.biocenter.helsinki.fi/sanspanz/. The source code is available under the GNU Public Licence v3.
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Gene Ontology: tool for the unification of biology
Ashburner, M., Ball, C. A., Blake, J. A., Botstein, D., Butler, H., Cherry, J. M., Davis, A. P., Dolinski, K., Dwight, S. S., Eppig, J. T., et al. (2000) · Nature Genetics · doi:10.1038/75556 · Cited by 43,206
BLAST+: architecture and applications
Camacho, C., Coulouris, G., Avagyan, V., Ma, N., Papadopoulos, J., Bealer, K., & Madden, T. L. (2009) · BMC Bioinformatics · doi:10.1186/1471-2105-10-421 · Cited by 22,074
Cited by
Rocafort, M., Bowen, J. K., Hassing, B., Cox, M. P., McGreal, B., de la Rosa, S., Plummer, K. M., Bradshaw, R. E., & Mesarich, C. H. (2022) · BMC Biology · doi:10.1186/s12915-022-01442-9 · Cited by 52
Unique Cell Surface Mannan of Yeast Pathogen Candida auris with Selective Binding to IgG
Yan, L., Xia, K., Yu, Y., Miliakos, A., Chaturvedi, S., Zhang, F., Chen, S., Chaturvedi, V., & Linhardt, R. J. (2020) · ACS Infectious Diseases · doi:10.1021/acsinfecdis.9b00450 · Cited by 47
Duru, I. C., Ylinen, A., Belanov, S., Pulido, A. A., Paulin, L., & Auvinen, P. (2021) · BMC Genomics · doi:10.1186/s12864-020-07338-8 · Cited by 40
Metadata
- Authors
- Törönen, P., Medlar, A., & Holm, L.
- Venue
- Nucleic Acids Research
- Publisher
- Oxford University Press (OUP)
- Published
- 2018-05-08
- Volume
- 46
- Issue
- W1
- Pages
- W84-W88
- ISSN
- 0305-1048 (ISSN-L)
- 1362-4962
- OpenAlex
- W2799828084
- Cited by
- 533
- References
- 2
- FWCI
- 13.03
- Type
- journal article
- Language
- en
- Open access
- gold
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