Glioblastoma in adults: a Society for Neuro-Oncology (SNO) and European Society of Neuro-Oncology (EANO) consensus review on current management and future directions

Wen, Patrick Y, Weller, Michael, Lee, Eudocia Quant, Alexander, Brian M, Barnholtz-Sloan, Jill S, Barthel, Floris P, Batchelor, Tracy T, Bindra, Ranjit S +32 more·2020·Neuro-Oncology

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Items 401–500 of 1,000

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  2. Association of pre-radiotherapy tumour burden and overall survival in newly diagnosed glioblastoma adjusted for MGMT promoter methylation status
    Ahmed Alafandi, Karin A. van Garderen, Stefan Klein, Sebastian R. van der Voort, Dimitris Rizopoulos, Burt Nabors, Roger Stupp, Michael Weller, Thierry Gorlia, Joerg‐Christian Tonn et al. · 2023 · European Journal of Cancer
  3. Genome-wide profiling of patient-derived glioblastoma stem-like cells reveals recurrent genetic and transcriptomic signatures associated with brain tumors
    Elisabetta Lazzarini, Domenico Alessandro Silvestris, Giuseppe Benvenuto, Daniela Osti, Luigi Fattore, Rosina Paterra, Gaetano Finocchiaro, Paolo Malatesta, Antonio Daga, Alberto Luigi Gallotti et al. · 2023 · Journal of Neuro-Oncology
  4. Re-irradiation for recurrent high-grade glioma: an analysis of prognostic factors for survival and predictors of radiation necrosis
    Daniel Moore-Palhares, Hanbo Chen, Julia Lee Keith, Michael H. Wang, Sten D. Myrehaug, Chia‐Lin Tseng, Jay S. Detsky, James Perry, Mary Jane Lim-Fat, Chris Heyn et al. · 2023 · Journal of Neuro-Oncology
  5. Decoding of the surfaceome and endocytome in primary glioblastoma cells identifies potential target antigens in the hypoxic tumor niche
    Kelin Gonçalves de Oliveira, Anna Bång-Rudenstam, Sarah Beyer, Axel Boukredine, Hugo Talbot A, Valeria Governa, Maria C. Johansson, Ann‐Sofie Månsson, Karin Forsberg‐Nilsson, Johan Bengzon et al. · 2024 · Acta Neuropathologica Communications
  6. Applications of nanotechnology in remodeling the tumour microenvironment for glioblastoma treatment
    Yulei Mu, Zhen Zhang, Huiqun Zhou, L. Ma, Dong‐An Wang · 2024 · Biomaterials Science
  7. The STELLAR trial: a phase II/III randomized trial of high-dose, intermittent sunitinib in patients with recurrent glioblastoma
    Jorien B.E. Janssen, Cyrillo G. Brahm, C.M.L. Driessen, Janine Nuver, Mariëtte Labots, Mathilde C.M. Kouwenhoven, Esther Sánchez Aliaga, Roelien H. Enting, Jan Cees de Groot, Annemiek Walenkamp et al. · 2024 · Brain Communications
  8. Metformin and its potential influence on cell fate decision between apoptosis and senescence in cancer, with a special emphasis on glioblastoma
    Melika Hajimohammadebrahim‐Ketabforoush, Alireza Zali, Mohammadreza Shahmohammadi, Amir Ali Hamidieh · 2024 · Frontiers in Oncology
  9. Glioblastoma mesenchymal subtype enhances antioxidant defence to reduce susceptibility to ferroptosis
    Simona D’Aprile, Simona Denaro, Alessandro Lavoro, Saverio Candido, Sebastiano Giallongo, Filippo Torrisi, Lucia Salvatorelli, Giacomo Lazzarino, Angela Maria Amorini, Giuseppe Lazzarino et al. · 2024 · Scientific Reports
  10. The Role of HDAC6 in Glioblastoma Multiforme: A New Avenue to Therapeutic Interventions?
    Francesco Spallotta, Barbara Illi · 2024 · Biomedicines
  11. Phase I Study of Adavosertib with Radiotherapy and Temozolomide in Newly Diagnosed Glioblastoma and Intratumoral Drug Levels in Recurrent Glioblastoma
    Eudocia Q. Lee, Brian Michael Alexander, Carlos Guillermo Romo, Jeffrey G. Supko, Nathalie Y.R. Agar, Zahra Talebi, Manmeet Singh Ahluwalia, Arati Suvas Desai, Jörg Dietrich, Thomas Joseph Kaley et al. · 2025 · Clinical Cancer Research
  12. Identifying new therapeutics for focused ultrasound-enhanced drug delivery in the management of glioblastoma
    Ryan Holman, Nathan Judson McDannold · 2025 · Frontiers in Oncology
  13. Immune cell infiltration into brain tumor microenvironment is mediated by Rab27-regulated vascular wall integrity
    Lata Adnani, Brian Meehan, Minjun Kim, Dongsic Choi, Christopher E. Rudd, Yasser Riazalhosseini, Janusz W. Rak · 2025 · Science Advances
  14. Glycoprotein NMB mediates bidirectional GSC-TAM interactions to promote tumor progression
    Yang Liu, Lizhi Pang, Fatima Khan, Junyan Wu, Fei Zhou, Craig Horbinski, Shideng Bao, Jennifer S. Yu, Justin Durla Lathia, Peiwen Chen · 2025 · JCI Insight
  15. The protein kinase LKB1 promotes self‐renewal and blocks invasiveness in glioblastoma
    Laia Caja, Mahsa Shahidi Dadras, Artur Mezheyeuski, Dorival Mendes Rodrigues‐Junior, Sijia Liu, Anna Webb, Maria Catalina Gomez‐Puerto, Peter ten Dijke, Carl‐Henrik Heldin, Aristidis Moustakas · 2021 · Journal of Cellular Physiology
  16. Using AI-Based Evolutionary Algorithms to Elucidate Adult Brain Tumor (Glioma) Etiology Associated with IDH1 for Therapeutic Target Identification
    Caitríona E. McInerney, Joanna A. Lynn, Alan R. Gilmore, Tom Flannery, Kevin M. Prise · 2022 · Current Issues in Molecular Biology
  17. CD95 gene deletion may reduce clonogenic growth and invasiveness of human glioblastoma cells in a CD95 ligand-independent manner
    Clara Quijano‐Rubio, Manuela Silginer, Michael Weller · 2022 · Cell Death Discovery
  18. Imaging in patients with glioblastoma: A national cohort study
    Maureen Dumba, Anna Fry, Jon Shelton, Thomas Calvert Booth, Brynmor Jones, Haris Shuaib, Matthew Williams · 2022 · Neuro-Oncology Practice
  19. CD73 in glioblastoma: Where are we now and what are the future directions?
    Nicolly Espíndola Gelsleichter, Juliana H. Azambuja, Dominique Santos Rubenich, Elizandra Braganhol · 2023 · Immunology Letters
  20. Progesterone Receptor Membrane Component 1 (PGRMC1) Modulates Tumour Progression, the Immune Microenvironment and the Response to Therapy in Glioblastoma
    Claudia Alexandra Dumitru, Hannah Schröder, Frederik Till Alexander Schäfer, Jan Friedrich Aust, Nina Kreße, Carl Ludwig Raven Siebert, Klaus‐Peter Stein, Aiden Haghikia, Ludwig Wilkens, Christian Mawrin et al. · 2023 · Cells
  21. Cerebrospinal Fluid Liquid Biopsies in the Evaluation of Adult Gliomas
    Allison R. Valerius, Mason Webb, Nouran Hammad, Ugur T. Sener, Rachna Malani · 2024 · Current Oncology Reports
  22. Therapy-Induced Transdifferentiation Promotes Glioma Growth Independent of EGFR Signaling
    Oh, Hwanhee, Hwang, Inah, Jang, Ja-Young, Wu, Lingxiang, Cao, Dongqing, Yao, Jun, Ying, Haoqiang, Li, Jian Yi, Yao, Yu, Hu, Baoli et al. · 2021 · Cancer Research
  23. Human organoid tumor transplantation identifies functional glioblastoma-microenvironment communication mediated by PTPRZ1
    Weihong Ge, Ryan L. Kan, Can Yilgor, Elisa Fazzari, Patricia R. Nano, Daria J. Azizad, Heer Shinglot, Matthew X. Li, Joyce Y. Ito, Christopher Tse et al. · 2026 · Cell Reports
  24. Multiple Irradiation Affects Cellular and Extracellular Components of the Mouse Brain Tissue and Adhesion and Proliferation of Glioblastoma Cells in Experimental System In Vivo
    Maxim O. Politko, Alexandra Y. Tsidulko, Oxana A. Pashkovskaya, Konstantin E. Kuper, Anastasia V. Suhovskih, Galina M. Kazanskaya, Lyubov S. Klyushova, Dmitry K. Sokolov, А. М. Волков, Evgenii E. Kliver et al. · 2021 · International Journal of Molecular Sciences
  25. Impacts of genotypic variants on survival following reoperation for recurrent glioblastoma
    Antonio Dono, Ping Zhu, Emma Holmes, Takeshi Takayasu, Jay‐Jiguang Zhu, Angel I. Blanco, Sigmund H. Hsu, Meenakshi B. Bhattacharjee, Leomar Y. Ballester, Dong Kim et al. · 2022 · Journal of Neuro-Oncology
  26. Added value of [18F]FDOPA PET to the management of high-grade glioma patients after their initial treatment: a prospective multicentre study
    Jacques Darcourt, David Chardin, Veronique Bourg, Jocelyn Gal, Renaud Schiappa, Marie Blonski, Pierre-Malick Koulibaly, Fabien Almairac, Lydiane Mondot, Florence Le Jeune et al. · 2023 · European Journal of Nuclear Medicine and Molecular Imaging
  27. TP53-PTEN-NF1 depletion in human brain organoids produces a glioma phenotype in vitro
    Sanjay Kumar Singh, Yan Wang, Ahmed Habib, Priyadarshini Mamindla, Chowdari V. Kodavali, Apeng Chen, Wencai Ma, Jing Wang, N. U. Farrukh Hameed, Baoli Hu et al. · 2023 · Frontiers in Oncology
  28. Pectolinarigenin and its derivatives: Bridging the gap between chemical properties and pharmacological applications
    Neeraj Kumar Patel, Rashi Kulshrestha, Asif Ahmad Bhat, Riya Mishra, Neelam Singla, Ritu Mehra Gilhotra, Gaurav Gupta · 2024 · Pharmacological Research - Modern Chinese Medicine
  29. Cellular diversity through space and time: adding new dimensions to GBM therapeutic development
    Amanda Johnson, Hernando López-Bertoni · 2024 · Frontiers in Genetics
  30. Prognostic relevance of radiological findings on early postoperative MRI for 187 consecutive glioblastoma patients receiving standard therapy
    Alexander Malcolm Rykkje, Jonathan Frederik Carlsen, Vibeke Andrée Larsen, Jane Skjøth‐Rasmussen, Ib Jarle Christensen, Michael Bachmann Nielsen, Hans Skovgaard Poulsen, Thomas Haargaard Urup, Adam Espe Hansen · 2024 · Scientific Reports
  31. TRIM24 Cooperates with Ras Mutation to Drive Glioma Progression through snoRNA Recruitment of PHAX and DNA‐PKcs
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  32. Impact of Sex Hormones on Glioblastoma: Sex-Related Differences and Neuroradiological Insights
    Jessica Rossi, Marialuisa Zedde, Manuela Napoli, Rosario Pascarella, Anna Pisanello, Giuseppe Biagini, Franco Valzania · 2024 · Life
  33. A novel nuclear RNA HSD52 scaffolding NONO/SFPQ complex modulates DNA damage repair to facilitate temozolomide resistance
    Nan Sun, Qun Chen, Hao Chen, Penggang Sun, Yuxiang Liu, Dan Song, Daohan Yu, Pandeng Wang, Yu Song, Jie Qin et al. · 2024 · Neuro-Oncology
  34. Aggressive resection of non-contrast-enhanced tumor provides varying benefits to glioblastoma, IDH-wildtype patients based on different clinical characteristics
    Lingyu Liu, Chihyi Liao, Siqi Ge, Xing Liu, Jiahan Dong, Shimeng Weng, Guoshi Huang, Zhong Zhang, Qiang Jin, Jiangwei Wang et al. · 2025 · Cancer Letters
  35. Fe3O4@Bi2S3 Nanoparticles Mediated MRI-Guided Precision Radiosensitization for Orthotopic Glioblastoma via External Magnetism
    Xiaowei Song, Liang Xiao, Lingling Xu, Yechun Jiang, Wanyue Fu, Benjin Chen, Wang Zheng, Haisheng Qian, Yongqiang Yu · 2025 · ACS Applied Materials & Interfaces
  36. Novel Thioredoxin reductase 1 inhibitor BS1801 relieves treatment resistance and triggers endoplasmic reticulum stress by elevating reactive oxygen species in glioma
    Yuanhao Chang, Jin Keun Chang, Jiayu Ji, Jing Sun, Huimin Hu, Bo Pang, Qi Zhang, Hanwei Yin, Huihui Zeng, Tao Jiang et al. · 2025 · Redox Biology
  37. Extracellular Vesicle Mediated Vascular Pathology in Glioblastoma
    Cristiana Spinelli, Nadim Tawil, Lata Adnani, Janusz W. Rak, Dongsic Choi · 2021 · Sub-cellular biochemistry/Subcellular biochemistry
  38. A Comparative Retrospective Study of Immunotherapy RANO Versus Standard RANO Criteria in Glioblastoma Patients Receiving Immune Checkpoint Inhibitor Therapy
    Xin Chen, Mary Jane Lim-Fat, Lei Qin, Angie Li, Annie G. Bryant, Camden Phillip Bay, Lu Gao, Nityanand P. Miskin, Zaiyi Liu, Julian Bryan Iorgulescu et al. · 2021 · Frontiers in Oncology
  39. Downregulation of STOX1 is a novel prognostic biomarker for glioma patients
    Fei-qin Jin, Lei Jin, Yanling Wang · 2021 · Open Life Sciences
  40. Role of magnetic resonance imaging following postoperative radiotherapy in clinical decision-making of patients with high-grade glioma
    Francesco Pasqualetti, Giulia Malfatti, MARTINA CANTARELLA, Alessandra Gonnelli, SABRINA MONTRONE, Nicola Montemurro, Giovanni Gadducci, Noemi Giannini, Ilaria Pesaresi, Paolo Perrini et al. · 2022 · La radiologia medica
  41. Identification of Candidate Genes Associated With Prognosis in Glioblastoma
    Rongjie Li, Qiulan Jiang, Chunhai Tang, Liechun Chen, Deyan Kong, Chun Zou, Yan Lin, Jiefeng Luo, Donghua Zou · 2022 · Frontiers in Molecular Neuroscience
  42. Impact of new molecular criteria on diagnosis and survival of adult glioma patients
    Danny Mortensen, Benedicte Parm Ulhøi, Slávka Lukacova, Jan Alsner, Magnus Stougaard, Jens Randel Nyengaard · 2022 · IBRO Neuroscience Reports
  43. Safety of Inhomogeneous Dose Distribution IMRT for High-Grade Glioma Reirradiation: A Prospective Phase I/II Trial (GLIORAD TRIAL)
    Patrizia Ciammella, Salvatore Cozzi, Andrea Botti, Lucia Giaccherini, Roberto Sghedoni, Matteo Orlandi, Manuela Napoli, Rosario Pascarella, Anna Pisanello, Marco Russo et al. · 2022 · Cancers
  44. Vaccination with Designed Neopeptides Induces Intratumoral, Cross-reactive CD4+ T-cell Responses in Glioblastoma
    Jian Wang, Tobias Weiß, Marian Christoph Neidert, Nora C. Toussaint, Reza Naghavian, Carla Sellés Moreno, Magdalena Foege, Paula Tomas Ojer, Gioele Medici, Ivan Jelčić et al. · 2022 · Clinical Cancer Research
  45. Lrig1 regulates the balance between proliferation and quiescence in glioblastoma stem cells
    Kirsty M. Ferguson, Carla Blin, Neza Alfazema, Ester Gangoso, Steven M. Pollard, María Ángeles Marqués‐Torrejón · 2022 · Frontiers in Cell and Developmental Biology
  46. Hypermethylation of HIC2 is a potential prognostic biomarker and tumor suppressor of glioma based on bioinformatics analysis and experiments
    Fei‐Fei Luo, Yifu Liao, Endong Cao, Yong Yang, Kai Tang, Dexiang Zhou, Dong Zhou, Haiping Cai · 2023 · CNS Neuroscience & Therapeutics
  47. Dose-dependent efficacy of bevacizumab in recurrent glioblastoma
    Jawad M. Melhem, Ali Tahir, Eirena Calabrese, Inga Granovskaya, Eshetu G. Atenafu, Arjun Sahgal, Mary Jane Lim-Fat, James Perry · 2023 · Journal of Neuro-Oncology
  48. Honokiol in glioblastoma recurrence: a case report
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  49. MUC17 mutations and methylation are associated with poor prognosis in adult-type diffuse glioma patients
    Gabriel Cardoso Machado, Valéria Pereira Ferrer · 2023 · Journal of the Neurological Sciences
  50. ALDH1A3 Segregated Expression and Nucleus-Associated Proteasomal Degradation Are Common Traits of Glioblastoma Stem Cells
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  51. Detection of mutation profiles and tumor mutation burden of cerebrospinal fluid circulating DNA by a cancer genomic panel sequencing in glioma patients
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  52. Towards an Established Intraoperative Oncological Favorable Tool: Results of Fluorescein-Guided Resection from a Monocentric, Prospective Series of 93 Primary Glioblastoma Patients
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  53. Metronomic Temozolomide in Heavily Pretreated Patients With Recurrent Isocitrate Dehydrogenase Wild-type Glioblastoma: A Large Real-Life Mono-Institutional Study
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  55. Melatonin Prevents Depression but Not Anxiety-like Behavior Produced by the Chemotherapeutic Agent Temozolomide: Implication of Doublecortin Cells and Hilar Oligodendrocytes
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  56. Drug resistance in glioblastoma: from chemo- to immunotherapy
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  57. Efficacy of combined tumor irradiation and KCa3.1-targeting with TRAM-34 in a syngeneic glioma mouse model
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  58. TARGET: A phase I/II open-label multicenter study to assess safety and efficacy of fexagratinib in patients with relapsed/refractory FGFR fusion-positive glioma
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  59. Re-irradiation treatment regimens for patients with recurrent glioma – Evaluation of the optimal dose and best concurrent therapy
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  60. Local therapy in glioma: An evolving paradigm from history to horizons (Review)
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  61. The Impact of MRI-Based Advanced Neuroimaging on Neurooncologists' Clinical Decision-Making in Patients With Posttreatment High-Grade Glioma: A Prospective Survey-Based Study
    Samir A. Dagher, Ho‐Ling Liu, Burak Berksu Ozkara, Susana Calle, Diana Kaya, Maria Kristine Gule-Monroe, Noah Nathan Chasen, Dawid Schellingerhout, Kim O. Learned, Komal B. Shah et al. · 2024 · American Journal of Roentgenology
  62. The global immune-nutrition-inflammation index (GINI) as a robust prognostic factor in glioblastoma patients treated with the standard stupp protocol
    Erkan Topkan, Nilüfer Kılıç Durankuş, Şükran Şenyürek, Düriye Öztürk, Ali Ayberk Beşen, Hüseyin Mertsoylu, Berrin Pehlivan, Uğur Selek · 2024 · International Journal of Immunopathology and Pharmacology
  63. Methionine cycle inhibition disrupts antioxidant metabolism and reduces glioblastoma cell survival
    Emma C. Rowland, Matthew D’Antuono, Anna M. Jermakowicz, Nagi G. Ayad · 2025 · Journal of Biological Chemistry
  64. Purine metabolism rewiring improves glioblastoma susceptibility to temozolomide treatment
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  65. Role of Colony Stimulating Factor 1 (CSF-1) and Its Receptor CSF1R: Macrophage Repolarization for Glioblastoma Treatment
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  66. A comprehensive framework for glioma surgery by the PIONEER Consortium and RANO resect group, part 1: intraoperative recommendations for mapping, monitoring, and decision making
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  67. Immune response to primary glioblastoma
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  68. Identification of a Novel Eight-Gene Risk Model for Predicting Survival in Glioblastoma: A Comprehensive Bioinformatic Analysis
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  69. Radio-pathomic maps of glioblastoma identify phenotypes of non-enhancing tumor infiltration associated with bevacizumab treatment response
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  70. Immunotherapy for Brain Tumors: Where We Have Been, and Where Do We Go From Here?
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  71. Innovating Strategies and Tailored Approaches in Neuro-Oncology
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  72. Advances in Chimeric Antigen Receptor (CAR) T-Cell Therapies for the Treatment of Primary Brain Tumors
    Christopher Mount, L. Nicolas Gonzalez Castro · 2022 · Antibodies
  73. Internalization study of nanosized zeolite crystals in human glioblastoma cells
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  74. Deciphering the Action of Neuraminidase in Glioblastoma Models
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  75. Preclinical development of an mRNA-based multiepitope immunotherapeutic for glioblastoma
    Lutz, Johannes, Feist, Randi K., Sonntag, Tim, Peguero-Sánchez, Esteban, Wolter, Katharina, Bick, Ronja, Bauer, Jens, Walz, Juliane S., Heidenreich, Regina · 2025 · Cancer Immunology, Immunotherapy
  76. Preservation of the Hypoxic Transcriptome in Glioblastoma Patient-Derived Cell Lines Maintained at Lowered Oxygen Tension
    Agata Góźdź, Bartosz Wojtaś, Patrycja Szpak, Paulina Szadkowska, Tomasz Czernicki, Andrzej Marchel, Katarzyna Wójtowicz, Wojciech Kaspera, Piotr Ładziński, Wojciech Szopa et al. · 2022 · Cancers
  77. Machine learning to improve interpretability of clinical, radiological and panel-based genomic data of glioma grade 4 patients undergoing surgical resection
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  78. Investigating cerebral perfusion with high resolution hyperpolarized [1‐13C]pyruvate MRI
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  79. Molecular Profiling and Targeted Therapies in Gliomas
    Yuli Felistia, Patrick Yung Wen · 2023 · Current Neurology and Neuroscience Reports
  80. Brain Tumors in Adolescents and Young Adults: A Review
    Julien Rousseau, Julie Bennett, Mary Jane Lim-Fat · 2023 · Seminars in Neurology
  81. Design and conduct of theranostic trials in neuro-oncology: Challenges and opportunities
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  82. Predicting glioblastoma progression using MR diffusion tensor imaging: A systematic review
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  85. Prognostic revalidation of RANO categories for extent of resection in glioblastoma: a reconstruction of individual patient data
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  86. The Clinical Role of miRNAs in the Development and Treatment of Glioblastoma
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  88. Multiparametric radiomics signature for predicting molecular genotypes in adult-type diffuse gliomas utilizing 18F-FET PET/MRI
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  89. Oncolytic virus-mediated immunomodulation in glioblastoma: Insights from clinical trials and challenges
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  90. Radiotherapy in Glioblastoma Multiforme: Evolution, Limitations, and Molecularly Guided Future
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  91. Knockdown of SUCLG2 inhibits glioblastoma proliferation and promotes apoptosis through LMNA acetylation and the mediation of H4K16la lactylation
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  92. Single cell spatial profiling of the matrisome identifies region-specific adhesion and signaling networks in glioblastoma
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