Cerebrospinal fluid analysis with the biofire filmarray meningitis/encephalitis molecular panel reduces length of hospital stay in patients with suspected central nervous system infections
Open accessAbstract
The Meningitis/Encephalitis Panel (MEP) is a sensitive and specific Food and Drug Administration-approved molecular diagnostic test for the 14 most common infectious etiologies of meningoencephalitis. Using a before-after controlled study design, MEP reduced length of hospital stay by 1.5 days, and this effect was mediated by the reduced time to final microbiology reporting.
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Implementation of the ME Panel into clinical practice has yielded mixed results.
“Implementation of the ME Panel into clinical practice has yielded mixed results.”
Some institutions have found a decreased length of stay associated with the ME Panel.
“Some institutions have found a decreased length of stay associated with the ME Panel [11,12].”
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References 9 · Cited by 32
- Authors
- DiDiodato, G., & Bradbury, N.
- Affiliations
- Centre for Education & Research, Barrie, Canada
- Royal Victoria Regional Health Centre (CA)
- Corresponding author
- DiDiodato, Giulio
- ORCID
- DiDiodato, Giulio
- Venue
- Open Forum Infectious Diseases
- Publisher
- Oxford University Press (OUP)
- Published
- 2019-03-05
- Volume
- 6
- Issue
- 4
- Pages
- ofz119-ofz119
- ISSN
- 2328-8957 (ISSN-L)
- PMC
- PMC6483125
- OpenAlex
- W2918909198
- Cited by
- 32
- References
- 9
- Citations by year
- 2026: 2 · 2025: 5 · 2024: 2 · 2023: 3 · 2022: 4 · 2021: 3 · 2020: 9 · 2019: 4
- FWCI
- 3.46
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Open Forum Infectious Diseases (publishedVersion, cc-by-nc-nd)
- PubMed Central (publishedVersion, cc-by-nc-nd)
- PubMed (publishedVersion)
- Funders
- bioMérieux
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Clinical Biochemistry › Bacterial Identification and Susceptibility Testing
- Life Sciences › Immunology and Microbiology › Microbiology › Bacterial Infections and Vaccines
- Health Sciences › Medicine › Infectious Diseases › Infectious Encephalopathies and Encephalitis
- Keywords
- cerebrospinal fluid, BioFire FilmArray, molecular diagnosis, meningoencephalitis, central nervous system infection, length of hospital stay
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