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Birth Weight and Perinatal Mortality: The Effect of Maternal Smoking

Wilcox, Allen J.·1993·American Journal of Epidemiology

Abstract

Infants born to mothers who smoke are a few hundred grams smaller, on average, than the infants of nonsmokers. This effect on fetal growth is regarded as evidence of the reproductive toxicity of cigarette smoking. In this paper, data from nearly 260,000 births in the state of Missouri (1980-1984) were analyzed using a method based on adjustment to relative birth weight. Two additional effects of smoking are demonstrated with this analysis; i.e., smokers are at higher risk of delivering very small preterm infants, and their infants have higher perinatal mortality at every relative birth weight. The latter is not apparent on an absolute birth weight scale and thus is not generally recognized. A supplementary analysis of births at high altitude is carried out to suggest that effects on fetal growth (whether from smoking or other factors) can occur independently of effects on mortality.

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Metadata

Authors
Wilcox, A. J.
Venue
American Journal of Epidemiology
Published
1993-05-15
Volume
137
Issue
10
Pages
1098-1104
ISSN
  • 0002-9262 (ISSN-L)
  • 1476-6256
OpenAlex
W2252663983
Cited by
180
References
0
FWCI
5.25
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Birth Weight and Perinatal Mortality: The Effect of Maternal Smoking. https://app.cochat.ai/papers/10.1093/oxfordjournals.aje.a116613
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Wilcox, A. J. (1993). Birth Weight and Perinatal Mortality: The Effect of Maternal Smoking. American Journal of Epidemiology. https://doi.org/10.1093/oxfordjournals.aje.a116613

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