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B VITAMIN DEFICIENCY AND NEUROPSYCHIATRIC SYNDROMES IN ALCOHOL MISUSE
Abstract
Alcohol misuse and alcohol withdrawal are associated with a variety of neuropsychiatric syndromes, some of which are associated with significant morbidity and mortality. B vitamin deficiency is known to contribute to the aetiology of a number of these syndromes, and B vitamin supplementation thus plays a significant part in prophylaxis and treatment. In particular, the Wernicke Korsakoff syndrome (WKS). due to thiamine deficiency, is a common condition in association with alcohol misuse, and is associated with high morbidity and mortality. Nicotinamide deficiency may result in a rarer condition, alcoholic pellagra encephalopathy, which often has a similar clinical presentation to WKS. This review considers the role of B vitamins in the aetiology and treatment of neuropsychiatric syndromes associated with alcohol misuse, with particular emphasis on WKS.
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Citations
Cited by
Neurocognitive impairment associated with alcohol use disorders: Implications for treatment.
Bates, M. E., Bowden, S. C., & Barry, D. (2002) · Experimental and Clinical Psychopharmacology · doi:10.1037/1064-1297.10.3.193 · Cited by 406
Thomson, A. D. (2002) · Alcohol and Alcoholism · doi:10.1093/alcalc/37.6.513 · Cited by 396
Self-citationWernicke-Korsakoff-syndrome: Under-recognized and under-treated
Isenberg-Grzeda, E., Kutner, H. E., & Nicolson, S. E. (2012) · Psychosomatics · doi:10.1016/j.psym.2012.04.008 · Cited by 253
Thiamine for prevention and treatment of Wernicke-Korsakoff Syndrome in people who abuse alcohol
Day, E., Bentham, P. W., Callaghan, R., Kuruvilla, T., & George, S. (2013) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd004033.pub3 · Cited by 158
Clinical management of alcohol withdrawal: A systematic review
Bharadwaj, B., & Kattimani, S. (2013) · Industrial Psychiatry Journal · doi:10.4103/0972-6748.132914 · Cited by 154
Metadata
- Authors
- COOK, C. C. H., HALLWOOD, P. M., & THOMSON, A. D.
- Venue
- Alcohol and Alcoholism
- Publisher
- Oxford University Press (OUP)
- Published
- 1998-07-01
- Volume
- 33
- Issue
- 4
- Pages
- 317-336
- ISSN
- 0735-0414 (ISSN-L)
- 1464-3502
- OpenAlex
- W2108134154
- Cited by
- 281
- References
- 0
- FWCI
- 3.29
- Type
- journal article
- Language
- en
- Open access
- closed
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- COOK, C. C. H., HALLWOOD, P. M., & THOMSON, A. D. (1998). B VITAMIN DEFICIENCY AND NEUROPSYCHIATRIC SYNDROMES IN ALCOHOL MISUSE. Alcohol and Alcoholism. https://doi.org/10.1093/oxfordjournals.alcalc.a008400
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