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Pathophysiology of accidental hypothermia
Abstract
Accidental hypothermia is an uncommon problem that affects people of all ages, but particularly the elderly. This review briefly outlines the aetiological factors that may predispose to hypothermia, with particular reference to the effects of sepsis, although the specific situation of cold-water immersion is not addressed. A more detailed analysis of the pathophysiology of hypothermia then examines the cardiovascular, haematological, neurological, respiratory, renal, metabolic, and gastrointestinal systems. Clinically relevant findings are highlighted and some associated management points are related to the physiological changes. Most of these changes are reversible on rewarming, and are resistant to pharmacological manipulation; some of the pathological effects are related more to the process of rewarming than to the hypothermia itself.
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Citations
Cited by
A Mathematical Model of Respiratory and Biothermal Dynamics in Brain Hypothermia Treatment
Gaohua, L., & Kimura, H. (2008) · IEEE Transactions on Biomedical Engineering · doi:10.1109/tbme.2007.912400 · Cited by 10
Metadata
- Authors
- Mallet, M. L.
- Venue
- QJM
- Publisher
- Oxford University Press (OUP)
- Published
- 2002-12-01
- Volume
- 95
- Issue
- 12
- Pages
- 775-785
- ISSN
- 0033-5622 (ISSN-L)
- 1460-2393
- OpenAlex
- W1987484538
- Cited by
- 312
- References
- 0
- FWCI
- 2.11
- Type
- journal article
- Language
- en
- Open access
- closed
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- Mallet, M. L. (2002). Pathophysiology of accidental hypothermia. QJM. https://doi.org/10.1093/qjmed/95.12.775
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
