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CAUSE OF DEATH IN RHEUMATOID ARTHRITIS
Abstract
A series of 489 consecutive patients with definite or classical rheumatoid arthritis was followed for a mean of 11.2 years. Cohort-analysis of the series showed a three-fold increase in mortality overall in comparison with age- and sex-specific rates in the general population. In patients first seen in hospital early in the course of the disease (less than 5 years from onset), the excess of deaths from circulatory, respiratory and musculoskeletal disorders was highly significant. Malignant disease and digestive system disorders accounted for a small excess of borderline significance. Patients who were referred later (greater than 5 years from onset) experienced, in addition, a highly significant excess of deaths from infections and disorders of the digestive and genito-urinary system but not from malignant neoplasms.
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Citations
Cited by
The mortality of rheumatoid arthritis
Wolfe, F., Mitchell, D. M., Sibley, J. T., Fries, J. F., Bloch, D. A., Williams, C. A., Spitz, P. W., Haga, M., Kleinheksel, S. M., & Cathey, M. A. (1994) · Arthritis & Rheumatism · doi:10.1002/art.1780370408 · Cited by 1,310
Sagar, S., Liu, P. P., & Cooper, L. T. (2012) · The Lancet · doi:10.1016/s0140-6736(11)60648-x · Cited by 743
Accelerated atherosclerosis: An extraarticular feature of rheumatoid arthritis?
Van Doornum, S., McColl, G., & Wicks, I. P. (2002) · Arthritis & Rheumatism · doi:10.1002/art.10089 · Cited by 606
The risk of infections associated with rheumatoid arthritis, with its comorbidity and treatment
Listing, J., Gerhold, K., & Zink, A. (2013) · Rheumatology · doi:10.1093/rheumatology/kes305 · Cited by 541
Survival, prognosis, and causes of death in rheumatoid arthritis
Mitchell, D. M., Spitz, P. W., Young, D. Y., Bloch, D. A., McShane, D. J., & Fries, J. F. (1986) · Arthritis & Rheumatism · doi:10.1002/art.1780290602 · Cited by 431
Metadata
- Authors
- PRIOR, P., SYMMONS, D. P. M., SCOTT, D. L., BROWN, R., & HAWKINS, C. F.
- Venue
- Rheumatology
- Publisher
- Oxford University Press (OUP)
- Published
- 1984
- Volume
- 23
- Issue
- 2
- Pages
- 92-99
- ISSN
- 1462-0324 (ISSN-L)
- 1462-0332
- OpenAlex
- W2132697065
- Cited by
- 247
- References
- 0
- FWCI
- 10.93
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: CAUSE OF DEATH IN RHEUMATOID ARTHRITIS. https://app.cochat.ai/papers/10.1093/rheumatology/23.2.92
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- PRIOR, P., SYMMONS, D. P. M., SCOTT, D. L., BROWN, R., & HAWKINS, C. F. (1984). CAUSE OF DEATH IN RHEUMATOID ARTHRITIS. Rheumatology. https://doi.org/10.1093/rheumatology/23.2.92
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
