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THE INCIDENCE OF RHEUMATOID ARTHRITIS IN THE UNITED KINGDOM: RESULTS FROM THE NORFOLK ARTHRITIS REGISTER
Abstract
This paper provides the first data on the incidence of RA based on a prospective population-based register. All new cases of inflammatory polyarthritis in the Norwich Health Authority are notified by general practitioners to the Norfolk Arthritis Register. The patients are then clinically evaluated by metrologists and blood taken for RF estimation. Cases of RA were defined as all those notified with an onset of symptoms in 1990; who presented by 31 December 1991; and who satisfied the 1987 ARA criteria for RA at the time of presentation. Two hundred and ten patients were notified in the defined time-frame, of whom 104 were classified as having RA. The annual incidence rate was 36/100,000 for women and 14/100,000 for men. RA was rare in men aged under 45 yr. The incidence in men rose steeply with age. The incidence in women rose up to age 45 yr, plateaued to age 75 yr, and fell in the very elderly.
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Citations
Cited by
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
The Wellcome Trust Case Control Consortium, Management Committee, Burton, P. R., Clayton, D. G., Cardon, L. R., Craddock, N., Deloukas, P., Duncanson, A., Kwiatkowski, D. P., McCarthy, M. I., et al. (2007) · Nature · doi:10.1038/nature05911 · Cited by 9,442
Self-citationEpidemiology and estimated population burden of selected autoimmune diseases in the United States
Jacobson, D. L., Gange, S. J., Rose, N. R., & Graham, N. M. H. (1997) · Clinical Immunology and Immunopathology · doi:10.1006/clin.1997.4412 · Cited by 1,667
Epidemiology of adult rheumatoid arthritis
ALAMANOS, Y., & DROSOS, A. (2005) · Autoimmunity Reviews · doi:10.1016/j.autrev.2004.09.002 · Cited by 916
Epidemiology and burden of illness of rheumatoid arthritis
Kvien, T. K. (2004) · PharmacoEconomics · doi:10.2165/00019053-200422001-00002 · Cited by 435
The need to address the burden of musculoskeletal conditions
Woolf, A. D., Erwin, J., & March, L. (2012) · Best Practice & Research Clinical Rheumatology · doi:10.1016/j.berh.2012.03.005 · Cited by 357
Metadata
- Authors
- SYMMONS, D. P. M., BARRETT, E. M., BANKHEAD, C. R., SCOTT, D. G. L., & SILMAN, A. J.
- Venue
- Rheumatology
- Publisher
- Oxford University Press (OUP)
- Published
- 1994
- Volume
- 33
- Issue
- 8
- Pages
- 735-739
- ISSN
- 1462-0324 (ISSN-L)
- 1462-0332
- OpenAlex
- W2113060075
- Cited by
- 464
- References
- 0
- FWCI
- 7.34
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: THE INCIDENCE OF RHEUMATOID ARTHRITIS IN THE UNITED KINGDOM: RESULTS FROM THE NORFOLK ARTHRITIS REGISTER. https://app.cochat.ai/papers/10.1093/rheumatology/33.8.735
- The paper
- SYMMONS, D. P. M., BARRETT, E. M., BANKHEAD, C. R., SCOTT, D. G. L., & SILMAN, A. J. (1994). THE INCIDENCE OF RHEUMATOID ARTHRITIS IN THE UNITED KINGDOM: RESULTS FROM THE NORFOLK ARTHRITIS REGISTER. Rheumatology. https://doi.org/10.1093/rheumatology/33.8.735
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
