Is the report of widespread body pain associated with long-term increased mortality? Data from the Mini-Finland Health Survey
Abstract
Objective To determine whether an observation in a UK study, that persons with chronic widespread pain are at long-term increased risk of cancer mortality, can be replicated in a different setting. Methods Subjects were participants aged >or=30 yrs in the Mini-Finland Health Survey conducted between 1979 and 1980. Information collected included prevalent pains at different joints throughout the body, demographic, anthropometric, lifestyle and occupational factors. During follow-up, until 1994, information on vital status and cause of death was obtained. Results 7182 persons participated (89.8%). The prevalence of widespread body pain (pain at four or more sites) was 20% in females and 12% in males, and during follow-up there were a total of 1647 deaths. The risk of death was not elevated amongst those with widespread pain [relative risk (RR): 0.86; 95% confidence interval (CI): 0.74-1.00], and in particular, those with widespread pain were at a slightly lower risk of several disease-specific causes of death and cancer death (RR: 0.64; 95% CI: 0.46-0.91). Conclusions This study of multiple pains has not confirmed a previous observation of an association between the reporting of widespread pain and subsequent increased risk of cancer death. Differences in the definitions used or, more probably, the population studied, in particular, a larger rural population with more multiple pains related to physical activity may account for the differences.
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Subsequent studies as well as the data of this study showed the importance of quantitative measures of body pain and of the key variables that comprise the SS scale in characterizing fibromyalgia.
“Subsequent studies as well as the data of this study showed the importance of (improved) quantitative measures of body pain (18 -22), and of the key variables that comprise the SS scale in characterizing fibromyalgia.”
From The American College of Rheumatology Preliminary Diagnostic Criteria for Fibromyalgia and Measurement of Symptom Severity (2010) · cites this paper as [21]
Cites
Macfarlane, G. J., Crombie, I. K., McBeth, J., & Silman, A. J. (2001) · BMJ · doi:10.1136/bmj.323.7314.662 · Cited by 223 · see citing works
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Wolfe, F., Clauw, D. J., Fitzcharles, M., Goldenberg, D. L., Katz, R. S., Mease, P., Russell, A. S., Russell, I. J., Winfield, J. B., & Yunus, M. B. (2010) · Arthritis Care & Research · doi:10.1002/acr.20140 · Cited by 3,952 · see citing works
Stone, J., Carson, A., Duncan, R., Coleman, R., Roberts, R., Warlow, C., Hibberd, C., Murray, G., Cull, R., Pelosi, A., et al. (2009) · Brain · doi:10.1093/brain/awp220 · Cited by 356 · see citing works
Severe chronic pain is associated with increased 10 year mortality. A cohort record linkage study
Torrance, N., Elliott, A. M., Lee, A. J., & Smith, B. H. (2010) · European Journal of Pain · doi:10.1016/j.ejpain.2009.07.006 · Cited by 276 · see citing works
- Authors
- Macfarlane, G. J., Jones, G. T., Knekt, P., Aromaa, A., McBeth, J., Mikkelsson, M., & Heliovaara, M.
- Affiliations
- University of Aberdeen (GB)
- Venue
- Rheumatology
- Publisher
- Oxford University Press (OUP)
- Published
- 2007-03-31
- Volume
- 46
- Issue
- 5
- Pages
- 805-807
- ISSN
- 1462-0324 (ISSN-L)
- 1462-0332
- OpenAlex
- W2096340441
- Cited by
- 59
- References
- 1
- Citations by year
- 2026: 2 · 2025: 1 · 2024: 2 · 2023: 2 · 2022: 2 · 2021: 1 · 2020: 3 · 2019: 1 · 2018: 2 · 2017: 3 · 2016: 4 · 2015: 3 · 2014: 3 · 2013: 6 · 2012: 2
- FWCI
- 2.33
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Lara D. Veeken (publishedVersion)
- PubMed (publishedVersion)
- ePrints Soton (University of Southampton) (submittedVersion)
- Research Explorer (The University of Manchester) (submittedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Fibromyalgia and Chronic Fatigue Syndrome Research
- Health Sciences › Medicine › Pharmacology › Musculoskeletal pain and rehabilitation
- Health Sciences › Medicine › Psychiatry and Mental health › Psychosomatic Disorders and Their Treatments
- Keywords
- chronic widespread pain, cancer mortality, mortality risk, rural population, physical activity
- MeSH terms
- Adult, Aged, Cause of Death, Epidemiologic Methods, Female, Fibromyalgia, Finland, Humans, Male, Middle Aged, Neoplasms, Age Distribution, Sex Distribution
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