Nuclear interactions in heavy ion transport and event-based risk models
Abstract
The physical description of the passage of heavy ions in tissue and shielding materials is of interest in radiobiology, cancer therapy and space exploration, including a human mission to Mars. Galactic cosmic rays (GCRs) consist of a large number of ion types and energies. Energy loss processes occur continuously along the path of heavy ions and are well described by the linear energy transfer (LET), straggling and multiple scattering algorithms. Nuclear interactions lead to much larger energy deposition than atomic-molecular collisions and alter the composition of heavy ion beams while producing secondary nuclei often in high multiplicity events. The major nuclear interaction processes of importance for describing heavy ion beams was reviewed, including nuclear fragmentation, elastic scattering and knockout-cascade processes. The quantum multiple scattering fragmentation model is shown to be in excellent agreement with available experimental data for nuclear fragmentation cross sections and is studied for application to thick target experiments. A new computer model, which was developed for the description of biophysical events from heavy ion beams at the NASA Space Radiation Laboratory (NSRL), called the GCR Event Risk-Based Model (GERMcode) is described.
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Radiation transport codes have been validated by extensive comparisons to measurements, and they have been combined with detailed descriptions of the space environment to enable accurate simulations behind spacecraft shielding or on planetary surfaces.
“radiation transport codes have been validated by extensive comparisons to measurements, and they have been combined with detailed descriptions of the space environment to enable accurate simulations behind spacecraft shielding or on planetary surfaces [Cucinotta et al., 2011;Kim et al., 2012].”
From Comparison of Martian surface ionizing radiation measurements from MSL-RAD with Badhwar-O'Neill 2011/HZETRN model calculations (2014) · cites this paper as Cucinotta et al., 2011
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Heavy ion carcinogenesis and human space exploration
Durante, M., & Cucinotta, F. A. (2008) · Nature Reviews Cancer · doi:10.1038/nrc2391 · Cited by 578 · see citing works
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Physical basis of radiation protection in space travel
Durante, M., & Cucinotta, F. A. (2011) · Reviews of Modern Physics · doi:10.1103/revmodphys.83.1245 · Cited by 528 · see citing works
Self-citationKim, M. Y., Cucinotta, F. A., Nounu, H. N., Zeitlin, C., Hassler, D. M., Rafkin, S. C. R., Wimmer‐Schweingruber, R. F., Ehresmann, B., Brinza, D. E., Böttcher, S., et al. (2014) · Journal of Geophysical Research: Planets · doi:10.1002/2013je004549 · Cited by 42 · see citing works
Self-citationRosi, S. (2018) · Brain Circulation · doi:10.4103/bc.bc_24_18 · Cited by 18 · see citing works
- Authors
- Cucinotta, F. A., Plante, I., Ponomarev, A. L., & Kim, M.-H. Y.
- Affiliations
- National Aeronautics and Space Administration (US)
- Corresponding author
- Cucinotta, F. A.
- Venue
- Radiation Protection Dosimetry
- Publisher
- Oxford University Press (OUP)
- Published
- 2011-01-17
- Volume
- 143
- Issue
- 2-4
- Pages
- 384-390
- ISSN
- 0144-8420 (ISSN-L)
- 1742-3406
- OpenAlex
- W2047259064
- Cited by
- 52
- References
- 1
- Citations by year
- 2026: 3 · 2025: 2 · 2024: 2 · 2023: 4 · 2021: 3 · 2020: 4 · 2019: 6 · 2018: 7 · 2017: 1 · 2016: 1 · 2015: 4 · 2014: 4 · 2013: 8 · 2012: 2
- FWCI
- 4.08
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Radiation Protection Dosimetry (publishedVersion)
- PubMed (publishedVersion)
- HighWire Press Open Archive (submittedVersion)
- Funders
- National Aeronautics and Space Administration
- National Synchrotron Radiation Laboratory
- Brookhaven National Laboratory
- Topics
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Radiation Therapy and Dosimetry
- Physical Sciences › Physics and Astronomy › Nuclear and High Energy Physics › Nuclear physics research studies
- Physical Sciences › Engineering › Computational Mechanics › Ion-surface interactions and analysis
- Keywords
- heavy ion transport, nuclear interactions, nuclear fragmentation, elastic scattering, linear energy transfer, straggling, multiple scattering, energy deposition, secondary nuclei, galactic cosmic rays, NASA Space Radiation Laboratory, space radiation, Mars missions, cancer therapy, radiation biology
- MeSH terms
- Computer Simulation, Radiation Dosage, Radiometry, Risk Factors, Scattering, Radiation, Models, Statistical, Risk Assessment, Heavy Ions
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