Effect of Nasal Spray, Positional Therapy, and the Combination Thereof in the Asymptomatic Snorer
Abstract
The benefits of using a nasal decongestant, sleeping on one's side and the combination thereof were studied in 20 asymptomatic male snorers. Both the apnea-hypopnea index (AHI) and snoring were evaluated. Four consecutive nocturnal polysomnographic studies were done. Night 1 was a control; the other 3 nights were randomly assigned to nasal decongestant, best sleeping position and a combination of the two. Results were calculated based on sleep period time. The mean control AHI +/- the standard error of the mean (SEM) was 17.5 +/- 6.5. AHI improved to 14.1 +/- 6.3 with sleep in the best position (p = 0.03). The AHI also improved to 13.2 +/- 6.04 with both nasal decongestant and position (p = 0.0012). Using nasal decongestant alone, the mean AHI was 18.1 +/- 6.3 (p = 0.765). During the control night, the mean number of snores/hour +/- SEM was 356 +/- 46.0. Using nasal decongestant alone, the mean number of snores was 381 +/- 50.4 (p = 0.50). With position alone, the mean number of snores was 356 +/- 46.0 (p = 0.8). Using the combination of nasal decongestant and position, mean snores were 352 +/- 48.9 (p = 0.91). In conclusion, a statistically significant improvement in AHI was produced using the general measures of altering the position of the body during sleep and by the combination of nasal decongestant and positional change. There was no significant change in snoring using any of these general measures.
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The Braver and Block report was a randomized, controlled trial and was assigned Evidence Level II.
“This report was a randomized, controlled trial and was assigned Evidence Level II.”
The short-acting nasal decongestant oxymetazoline, which has an established rebound rhinorrhea later in the night, may not be an effective therapy in all OSA patients.
“The findings from this study, therefore, suggest that this short-acting nasal decongestant with an established rebound rhinorrhea later in the night may not be an effective therapy in all OSA patients.”
In a randomized controlled trial of 20 males with OSA, postural therapy alone and in combination with oxymetazoline nasal spray significantly reduced AHI, but oxymetazoline nasal spray alone had no effect.
“This study suggested that postural therapy alone and in combination with oxymetazoline nasal spray significantly reduced AHI, but oxymetazoline nasal spray alone had no effect.”
Patients with nasal congestion may benefit from nasal corticosteroids, but it is unlikely that this therapy alone would sufficiently treat OSA.
“In conclusion, patients with nasal congestion may benefit from nasal corticosteroids, but it is unlikely that this therapy alone would sufficiently treat OSA.”
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- Authors
- Braver, H. M., & Block, A. J.
- Affiliations
- University of Florida Health (US)
- Veterans Health Administration (US)
- Corresponding author
- Block, A. Jay
- Venue
- Sleep
- Publisher
- Oxford University Press (OUP)
- Published
- 1994-09
- Volume
- 17
- Issue
- 6
- Pages
- 516-521
- ISSN
- 0161-8105 (ISSN-L)
- 1550-9109
- OpenAlex
- W124716182
- Cited by
- 72
- References
- 3
- Citations by year
- 2022: 1 · 2021: 1 · 2020: 2 · 2019: 1 · 2018: 2 · 2017: 1 · 2016: 4 · 2015: 3 · 2014: 6 · 2013: 3 · 2012: 6
- FWCI
- 0.91
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- SLEEP (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Physiology › Obstructive Sleep Apnea Research
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and related disorders
- Health Sciences › Medicine › Surgery › Nasal Surgery and Airway Studies
- Keywords
- snoring, nasal decongestants, positional therapy, side sleeping, apnea-hypopnea index, obstructive sleep apnea, nocturnal polysomnography
- MeSH terms
- Adult, Combined Modality Therapy, Humans, Male, Middle Aged, Posture, Sleep Apnea Syndromes, Snoring, Nasal Decongestants, Polysomnography
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