Reactive oxygen species alter brain endothelial tight junction dynamics via RhoA, PI3 kinase and PKB signaling

Schreibelt, Gerty, Kooij, Gijs, Reijerkerk, Arie, van Doorn, Ruben, Gringhuis, Sonja I., van der Pol, Susanne, Weksler, Babette B., Romero, Ignacio A. +6 more·2007·The FASEB Journal

Cited by (347)

Items 301–347 of 347

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  2. Transport pathways across the blood-brain barrier for waste clearance and drug delivery
    Lea S. Gröbner, Claus U. Pietrzik · 2026 · Fluids and Barriers of the CNS
  3. Inhibition of GSK3α/β promotes increased pulmonary endothelial permeability to albumin by reactive oxygen/nitrogen species
    Paul H. Neumann, Hiba Alsaffar, Nancy Gertzberg, Arnold Johnson · 2013 · Pulmonary Pharmacology & Therapeutics
  4. Iatrogenic Neuropathology of Systemic Therapies
    Matthew Torre, Mel Β. Feany · 2020 · Surgical pathology clinics
  5. Dipyridamole Treatment Prior to Stroke Onset: Examining Post-stroke Cerebral Circulation and Outcome in Rabbits
    Christopher D. d’Esterre, Kenneth M. Tichauer, Richard Ivan Aviv, Wolfgang G. Eisert, Ting‐Yim Lee · 2011 · Translational Stroke Research
  6. In vitro fertilization exacerbates stroke size and neurological disability in wildtype mice
    Nicole R. Bonetti, Theo Arthur Meister, Rodrigo Soria, Alexander T. Akhmedov, Luca Liberale, Stefano Ministrini, Afzal M. Dogar, Thomas Felix Lüscher, Franz H. Messerli, Emrush Rexhaj et al. · 2021 · International Journal of Cardiology
  7. Cellular Tight Junctions as Mediators of Adverse Effects
    Yula Sambuy · 2009 · General, Applied and Systems Toxicology
  8. Integrated focused ultrasound and electromagnetic actuation (FUEM) system for enhanced targeted drug delivery in brain cancer treatment
    Hyeonwoo Kee, Hyoryong Lee, Joowon Park, Saeeun Jang, Sukho Park · 2025 · Journal of Controlled Release
  9. Reactive Oxygen Species and Cerebrovascular Diseases
    Alyson A. Miller, T. Michael De Silva, Grant Raymond Drummond, Christopher Graeme Sobey, Sophocles Chrissobolis · 2014 · Springer eBooks
  10. Role of Fibrinogen in Vascular Cognitive Impairment in Traumatic Brain Injury
    Nino Muradashvili, Suresh Chand Tyagi, David G. Lominadze · 2018 · InTech eBooks
  11. Calcium-activated potassium channel activator down-regulated the expression of tight junction protein in brain tumor model in rats
    Yan-ting Gu, Yixue Xue, Xiuyan Wei, Hua Zhang, Yan Li · 2011 · Neuroscience Letters
  12. Consideration for future in vitro BBB models — technical development to investigate the drug delivery to the CNS
    Kaoru Sato · 2018 · Folia Pharmacologica Japonica
  13. Oxidative Stress and Brain Endothelial Cells
    Maria Teresa Rizzo, Muhammad Saquib, H. ANNE LEAVER · 2014 · Springer eBooks
  14. Cerebrovascular Unit Activation and Response Following Traumatic Brain Injury
    Amaya Arbogast, Matthew N. Montoya Rush, Sarbani Ghosh, Sravanthi Bandla, Isaiah R. Turnbull, Grace Martin Niziolek · 2025 · Shock
  15. In Vitro 2D and 3D Cell Models of the Human Blood-Brain Barrier: Demonstrating the Beneficial Influence of Shear Stress on Brain Microvascular Endothelial Cell Phenotype
    Keith D. Rochfort, Philip M. Cummins · 2025 · Neuromethods
  16. NADPH Oxidases and Blood-Brain Barrier Dysfunction in Stroke
    Timo Kahles, Sabine Heumüller-Klug, Ralf Peter Brandes · 2010 · Humana Press eBooks
  17. Proteinopathies and Neurotrauma: Update on Degenerative Cascades.
    Stephan S. Quintin, Zachary A. Sorrentino, Yusuf Mehkri, Sai Sriram, Sydney Weisman, Caroline Grace Davidson, Grace M. Lloyd, Eric Sung, John Figg, Brandon Peter Lucke-Wold · 2022 · PubMed
  18. Proteomic screening of cerebrospinal fluid: Candidate proteomic biomarkers for sample stability and experimental autoimmune encephalomyelitis
    Ann Therese Isabell Rosenling · 2010 · University of Groningen research database (University of Groningen / Centre for Information Technology)
  19. Blood-brain barrier permeability and brain immunity in yellow catfish (Pelteobagrus fulvidraco) responding to Edwardsiella ictaluri infection
    Qin Wang, Li Shen, Mengge Guo, Bingchao Wang, Huimin Liu, Ke Xiao, Ze-Chao Shi, Wei Ji · 2025 · Aquaculture
  20. EndMT in vascular cognitive impairment and dementia: mechanisms, evidence gaps, and therapeutic opportunities
    Juhyun Song · 2026 · Molecular Medicine
  21. Microglia-driven neuroinflammation in ischemic stroke: insights from high altitude hypoxia
    Shafa Khan, Armiya Sultan, Mohd. Sadik, Mohammad Zahid Ashraf · 2026 · Neuroscience
  22. Improving Acute Stroke Management with CT Perfusion Imaging: Approaches to Treatment Guidance and Brain Tissue Salvage
    Christopher D. d’Esterre · 2013 · Scholarship@Western (Western University)
  23. Disease Influence on BBB Transport in Inflammatory Disorders
    Geert J. Schenk, Gijs Kooij, Arie Reijerkerk, Helga E. de Vries · 2013 · AAPS advances in the pharmaceutical sciences series
  24. Glial Support of Blood–Brain Barrier Integrity: Molecular Targets for Novel Therapeutic Strategies in Stroke
    Patrick T. Ronaldson, Thomas P. Davis · 2016 · Springer series in translational stroke research
  25. The induction of traumatic brain injury by blood brain barrier disruption
    Mark D. Skopin · 2011 · OhioLink ETD Center (Ohio Library and Information Network)
  26. Evaluation of the hCMEC/D3 cell line, a new "in vitro" model of the human blood-brain barrier for transport and gene regulation studies
    Birk Poller · 2009 · edoc (University of Basel)
  27. Hypoxia/Reoxygenation Stress Modulates Atorvastatin Transport at the Blood-Brain Barrier: A Role for Organic Anion Transporting Polypeptide
    Brandon J. Thompson · 2014 · UA Campus Repository (The University of Arizona)
  28. Leukocyte Entry into the Brain
    Katerina Dorovini‐Zis, Donald K. Wong, Kenneth Liu · 2015
  29. EFEITO DA SECÇÃO DO NERVO CIÁTICO, COMO MODELO DE DOR NEUROPÁTICA, SOBRE MARCADORES DE ESTRESSE OXIDATIVO E DEFESAS ANTIOXIDANTES NA MEDULA ESPINAL DE RATOS
    Básicas Da Saúde · 2007
  30. Oxidant-Induced Models of Vascular Leak
    Rengasayee Veeraraghavan, Narasimham L. Parinandi, Thomas J. Hund · 2020 · Biological magnetic resonance
  31. Examining the protective effects of sesamol on oxidative stress associated blood -brain barrier dysfunction in streptozotocin-induced diabetic rats
    Reyna L. VanGilder · 2009
  32. Three-dimensional in vitro model of the device-tissue interface reveals innate neuroinflammation can be mitigated by antioxidant ceria nanoparticles
    Elaina Atherton, Yue Hu, Sophie Brown, Emily Papiez, Vivian Ling, Vicki L. Colvin, David A. Borton · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
  33. Leukocyte Entry into the Brain
    Katerina Dorovini‐Zis, Donald K. Wong, Kenneth Liu · 2015 · CRC Press eBooks
  34. Cytoskeleton Elements Contribute to Prion Peptide-Induced Endothelial Barrier Breakdown in a Blood–Brain Barrier In Vitro System
    I. Cooper, K. Cohen-Kashi-Malina, Y. Levin, A. Gabashvili, Boaz Mohar, A. Cagnotto, M. Salmona, V. Teichberg · 2022 · International Journal of Molecular Sciences
  35. MPS for Blood Brain Barrier
    Kaoru Sato, Michiya Matsusaki · 2022 · YAKUGAKU ZASSHI
  36. Antiretroviral therapy and its cerebral vascular toxicity
    Harrison Rudd, Michal J. Toborek · 2024 · Elsevier eBooks
  37. Neurovascular mitochondrial susceptibility impacts blood-brain barrier function and behavior
    Alexis Mary Crockett, Hania Kébir, M. C. Vélez Colόn, Daniel Maxim Iascone, B. Cielieski, Adam J. Rossano, Amita Sehgal, Stewart A. Anderson, Jorge Ivan Alvarez · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
  38. Study on the Correlation between TDP-43, HDAC6, Prdx1 Proteins and Brain Oxygen Levels and Cognitive Function in Schizophrenia
    Ziling Tang, Han Zhang, Yanwen Lin, Ran Hu, Xiaoyue Hu, Xianlai Jin, Gaoxia Wen, Peng Xiong · 2025 · Research Square
  39. The role of NADPH oxidase in blood -brain barrier dysfunction following stroke in aged rats
    Kimberly A. Kelly · 2009
  40. Physiology and Pathophysiology of Cerebral Microcirculation
    Turgay Dalkara · 2014 · Springer eBooks
  41. Additional file 2 of Epigenetics and stroke: role of DNA methylation and effect of aging on blood–brain barrier recovery
    Phillips, Chelsea M., Svetlana M. Stamatovic, Keep, Richard F., Anuska V. Andjelkovic · 2024 · Figshare
  42. Additional file 1 of Epigenetics and stroke: role of DNA methylation and effect of aging on blood–brain barrier recovery
    Phillips, Chelsea M., Svetlana M. Stamatovic, Keep, Richard F., Anuska V. Andjelkovic · 2024 · Figshare
  43. NX210c Demonstrates Therapeutic Potential to Restore Blood–Brain Barrier in a QSP Model of Relapsing–Remitting Multiple Sclerosis
    Giulia Russo, Fianne L. P. Sips, Simona Catozzi, Pauline Bambury, Annette Janus, Mario Torchia, Valentina Di Salvatore, Luca Emili, Daniel Röshammar, Francesco Pappalardo et al. · 2026 · International Journal of Molecular Sciences
  44. Impact de l’inflammation sur la pharmacocinétique des médicaments
    Florian Simon · 2020 · theses.fr (ABES)
  45. Battle of the wall for aromatic “orifice-opening” agents: defending and breaching the blood-brain barrier
    Xiaoman Yang, Jing Zhang, Hao Yu, Yulei Zhao, Guanqun Hou, Shijun Wang, Bingbing Han · 2026 · Chinese Journal of Natural Medicines
  46. Mitochondrial control of blood-brain barrier homeostasis in neuroinflammatory psychiatric disorders
    Larli Misael Pérez-López, Alberto Camacho-Morales, Ivón Howland Álvarez, Antonio Alí Pérez‐Maya · 2026 · Frontiers in Molecular Neuroscience
  47. OXIDATIVE STRESS ALTERS BLOOD-BRAIN BARRIER INTEGRITY
    Jeffrey J. Lochhead · 2011 · UA Campus Repository (The University of Arizona)