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Cited by 159

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Sclerosing Cholangitis after Continuous Hepatic Artery Infusiori of FUDR

Open access
KEMENY, M. MARGARET, BATTIFORA, HECTOR, BLAYNEY, DOUGLAS W., CECCHI, GARY, GOLDBERG, DAVID A., LEONG, LUCILLE A., MARGOLIN, KIM A., TERZ, JOSE J.·1985·Annals of Surgery

Abstract

Eight of 46 (17.4%) patients treated in our trial of continuous hepatic artery infusion (CHAI) of fluorodeoxyuridine (FUDR) by Infusaid pump developed biliary strictures. The lesions were clinically, radiographically, and pathologically identical to the idiopathic sclerosing cholangitis frequently seen in association with inflammatory bowel disease. Treatment included immediate cessation of intraarterial FUDR, and surgical or percutaneous drainage of the biliary tree if it was dilated. Two of the eight patients died of the complication. Three patients stabilized after biliary system drainage, and two patients improved on observation only. The pathogenesis of this complication is not understood. This report details the clinical and pathological features of this entity.

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Metadata

Authors
KEMENY, M. M., BATTIFORA, H., BLAYNEY, D. W., CECCHI, G., GOLDBERG, D. A., LEONG, L. A., MARGOLIN, K. A., & TERZ, J. J.
Venue
Annals of Surgery
Published
1985-08
Volume
202
Issue
2
Pages
176-181
ISSN
0003-4932 (ISSN-L)
OpenAlex
W2036509953
Cited by
159
References
0
FWCI
9.01
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Sclerosing Cholangitis after Continuous Hepatic Artery Infusiori of FUDR. https://app.cochat.ai/papers/10.1097/00000658-198508000-00007
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KEMENY, M. M., BATTIFORA, H., BLAYNEY, D. W., CECCHI, G., GOLDBERG, D. A., LEONG, L. A., MARGOLIN, K. A., & TERZ, J. J. (1985). Sclerosing Cholangitis after Continuous Hepatic Artery Infusiori of FUDR. Annals of Surgery. https://doi.org/10.1097/00000658-198508000-00007

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.