The DOI matches its Crossref record; 23 of the 23 references it cites were found in a registry or an index.
Meta-Analysis of Measures of Sexual Activity and Prostate Cancer
Abstract
We conducted a meta-analysis of the association between prostate cancer and aspects of sexual activity. The data suggest an elevated relative risk (RR) of prostate cancer among men with a history of sexually transmitted infections. This was observed with both random- and fixed-effects models (RR = 1.4; 95% CI = 1.2-1.7; N = 17 studies; heterogeneity P = 0.14), especially for syphilis (RR = 2.3; 95% CI = 1.3-3.9; N = 6; heterogeneity P = 0.47). Risk of prostate cancer is also associated with increasing frequency of sexual activity (RR = 1.2 for an increase of three times per week; 95% CI = 1.1-1.3; N = 12). However, these studies are heterogeneous (P < 0.001). Increasing number of sexual partners is also associated with prostate cancer (RR = 1.2 for an increase of 20 partners; 95% CI = 1.1-1.3; N = 16; heterogeneity P = 0.11). The data do not support associations with multiple marriages, age at first intercourse, or age at first marriage. These results indicate an association between prostate cancer and sexually transmitted infections, suggesting that infections may represent one mechanism through which prostate cancer develops. The mechanism through which frequency of sexual activity may be related to prostate cancer is unclear.
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Cites
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Prostate Cancer: A Current Perspective
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DIET AND PROSTATIC CANCER: A CASE-CONTROL STUDY IN HAWAII1
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Cited by
Inflammation in prostate carcinogenesis
De Marzo, A. M., Platz, E. A., Sutcliffe, S., Xu, J., Grönberg, H., Drake, C. G., Nakai, Y., Isaacs, W. B., & Nelson, W. G. (2007) · Nature Reviews Cancer · doi:10.1038/nrc2090 · Cited by 1,621
Hsing, A. (2006) · Frontiers in Bioscience · doi:10.2741/1891 · Cited by 447
Epidemiologic association between prostatitis and prostate cancer
Dennis, L. K., Lynch, C. F., & Torner, J. C. (2002) · Urology · doi:10.1016/s0090-4295(02)01637-0 · Cited by 403
Self-citationProstate carcinogenesis and inflammation: emerging insights
Palapattu, G. S., Sutcliffe, S., Bastian, P. J., Platz, E. A., De Marzo, A. M., Isaacs, W. B., & Nelson, W. G. (2005) · Carcinogenesis · doi:10.1093/carcin/bgh317 · Cited by 388
THE ROLE OF INFLAMMATION IN THE PATHOGENESIS OF PROSTATE CANCER
NELSON, W. G., DE MARZO, A. M., DeWEESE, T. L., & ISAACS, W. B. (2004) · Journal of Urology · doi:10.1097/01.ju.0000142058.99614.ff · Cited by 386
Metadata
- Authors
- Dennis, L. K., & Dawson, D. V.
- Venue
- Epidemiology
- Published
- 2002-01
- Volume
- 13
- Issue
- 1
- Pages
- 72-79
- ISSN
- 1044-3983 (ISSN-L)
- OpenAlex
- W1987395035
- Cited by
- 274
- References
- 23
- FWCI
- 2.83
- Type
- journal article
- Language
- en
- Open access
- closed
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
