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ACOG Practice Bulletin No. 77: Screening for Fetal Chromosomal Abnormalities
Abstract
In the last decade, numerous markers and strategies for Down syndrome screening have been developed. Algorithms that combine ultrasound and serum markers in the first and second trimesters have been evaluated. Furthermore, the practice of using age cutoffs to determine whether women should be offered screening or invasive diagnostic testing has been challenged. The purpose of this document is to 1) present and evaluate the best available evidence for the use of ultrasonographic and serum markers for selected aneuploidy screening in pregnancy and 2) offer practical recommendations for implementing Down syndrome screening in practice.
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Citations
Cited by
Chromosomal microarray versus karyotyping for prenatal diagnosis
Wapner, R. J., Martin, C. L., Levy, B., Ballif, B. C., Eng, C. M., Zachary, J. M., Savage, M., Platt, L. D., Saltzman, D., Grobman, W. A., et al. (2012) · New England Journal of Medicine · doi:10.1056/nejmoa1203382 · Cited by 1,412
Health Supervision for Children and Adolescents With Down Syndrome
Bull, M. J., Trotter, T., Santoro, S. L., Christensen, C., Grout, R. W., & THE COUNCIL ON GENETICS (2022) · Pediatrics · doi:10.1542/peds.2022-057010 · Cited by 332
Pergament, E., Cuckle, H., Zimmermann, B., Banjevic, M., Sigurjonsson, S., Ryan, A., Hall, M. P., Dodd, M., Lacroute, P., Stosic, M., et al. (2014) · Obstetrics & Gynecology · doi:10.1097/aog.0000000000000363 · Cited by 284
Selective analysis of cell‐free DNA in maternal blood for evaluation of fetal trisomy
Sparks, A. B., Wang, E. T., Struble, C. A., Barrett, W., Stokowski, R., McBride, C., Zahn, J., Lee, K., Shen, N., Doshi, J., et al. (2012) · Prenatal Diagnosis · doi:10.1002/pd.2922 · Cited by 266
Reddy, U. M., Abuhamad, A. Z., Levine, D., Saade, G. R., & Participants, F. T. F. I. W. I. (2014) · Journal of Ultrasound in Medicine · doi:10.7863/ultra.33.5.745 · Cited by 207
Metadata
- Venue
- Obstetrics & Gynecology
- Published
- 2007-01
- Volume
- 109
- Issue
- 1
- Pages
- 217-228
- ISSN
- 0029-7844 (ISSN-L)
- OpenAlex
- W4241487444
- Cited by
- 581
- References
- 0
- FWCI
- 37.48
- Type
- journal article
- Language
- en
- Open access
- closed
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- ACOG Practice Bulletin No. 77: Screening for Fetal Chromosomal Abnormalities. (2007). Obstetrics & Gynecology. https://doi.org/10.1097/00006250-200701000-00054
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
