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Cited by 299Ear Surgery and Otitis MediaPneumonia and Respiratory InfectionsOtolaryngology and Infectious Diseases

The DOI matches its Crossref record; 33 of the 33 references it cites were found in a registry or an index.

Bacteriology of acute otitis media in a cohort of Finnish children followed for the first two years of life.

KILPI, TERHI, HERVA, ELJA, KAIJALAINEN, TARJA, SYRJÄNEN, RITVA, TAKALA, AINO K.·2001·The Pediatric Infectious Disease Journal
DOI 10.1097/00006454-200107000-00004
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Abstract

BACKGROUND: Timely information on the bacteriology of primary, noncomplicated acute otitis media (AOM) may today be needed more than ever, because of the increasing antimicrobial resistance of its major bacterial causes and because of the potential of new pneumococcal and other bacterial vaccines for prevention of AOM. METHODS: The study followed 329 children from 2 to 24 months of age at scheduled healthy visits and sick visits at the study clinic. Whenever AOM was diagnosed during the follow-up, myringotomy was performed and middle ear fluid was aspirated for bacterial culture. RESULTS: At least one middle ear fluid sample was available from 772 AOM events; Streptococcus pneumoniae (Pnc) was isolated in 201 (26%), Moraxella catarrhalis (Mc) in 177 (23%) and Haemophilus influenzae (Hi) in 174 events (23%). The incidence of Pnc AOM peaked at 12 months of age, whereas the incidence of Mc AOM showed the first peak at 6 months and Hi AOM at 20 months. Pnc AOM showed less prominent seasonality in occurrence than Mc and Hi AOM. Hi was a rare cause of the first 2 AOM episodes (13%) but became increasingly common from the third episode on (32% on average). CONCLUSIONS: Pnc, Mc and Hi were almost equally common findings in AOM. Pnc seems to be the most pathogenic of these three, the role of Mc is increasing and Hi is clearly associated with recurrent AOM.

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Crossref · 10.1097/00006454-200107000-00004

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Research works printed but not linked: 6

  1. Murphy, 1996, Microbiol Rev, 60, 267, 10.1128/MMBR.60.2.267-279.1996 · DOI
  2. Wirth, 1928, Passow-Schaefer Beitr, 26, 190
  3. Paraskaki, 1995, J Chemother, 7, 142
  4. Lahikainen, 1953, Acta Otolaryngol Stockh, Suppl, 107
  5. Austrian, 1977, Johns Hopkins Med J, 141, 104
  6. Kamme, 1970, 2, 183

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Metadata

Authors
KILPI, T., HERVA, E., KAIJALAINEN, T., SYRJÄNEN, R., & TAKALA, A. K.
Venue
The Pediatric Infectious Disease Journal
Publisher
Ovid Technologies (Wolters Kluwer Health)
Published
2001-07
Volume
20
Issue
7
Pages
654-662
ISSN
0891-3668 (ISSN-L)
DOI
10.1097/00006454-200107000-00004
OpenAlex
W2061486920
Cited by
299
References
33
Citations by year
2026: 2 · 2024: 1 · 2023: 2 · 2022: 3 · 2021: 1 · 2020: 2 · 2019: 5 · 2018: 3 · 2017: 10 · 2016: 10 · 2015: 12 · 2014: 17 · 2013: 13 · 2012: 16
FWCI
25.13
Type
journal article
Language
en
Open access
closed
Locations
  • The Pediatric Infectious Disease Journal (publishedVersion)
  • PubMed (publishedVersion)
  • STM:n Hallinnonalan avoin julkaisuarkisto (Julkari) (submittedVersion)
Funders
  • National Taiwan University Hospital
  • NIH Clinical Center
Topics
  • Health Sciences › Medicine › Otorhinolaryngology › Ear Surgery and Otitis Media
  • Health Sciences › Medicine › Epidemiology › Pneumonia and Respiratory Infections
  • Health Sciences › Medicine › Infectious Diseases › Otolaryngology and Infectious Diseases
Keywords
acute otitis media, bacterial etiology, Streptococcus pneumoniae, Moraxella catarrhalis, Haemophilus influenzae, middle ear fluid, recurrent otitis media, seasonal variation, age-related incidence, infants, Finnish children
MeSH terms
Acute Disease, Anti-Bacterial Agents, Moraxella catarrhalis, Child, Preschool, Female, Finland, Haemophilus Infections, Haemophilus influenzae, Humans, Infant, Male, Otitis Media, Pneumococcal Infections, Recurrence, Serotyping, Streptococcus pneumoniae, Suction, Cohort Studies, Neisseriaceae Infections, Pneumococcal Vaccines

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