Human catechol-O-methyltransferase pharmacogenetics: description of a functional polymorphism and its potential application to neuropsychiatric disorders

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2. Significant association between catechol-O-methyltransferase (COMT) Val158/108Met polymorphism and cognitive function in veterans with PTSD
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3. Polymorphic catechol-O-methyltransferase gene, duration of estrogen exposure, and breast cancer risk: A nested case–control study in Taiwan
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4. Catecholamine pathway gene variation is associated with norepinephrine and epinephrine concentrations at rest and after exercise
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5. Haplotype analysis of the COMT‐ARVCF gene region in Israeli anorexia nervosa family trios
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6. Prefrontal cortex and schizophrenia
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7. The psychosis proneness: psychosis persistence model as an explanation for the association between urbanicity and psychosis
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8. Genes of the dopaminergic system selectively modulate top-down but not bottom-up attention
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9. COMTVal158Met polymorphism influences the susceptibility to framing in decision‐making: OFC‐amygdala functional connectivity as a mediator
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10. Interaction Between Val158Met Catechol‐O‐Methyltransferase Polymorphism and Social Cognitive Functioning in Schizophrenia: Pilot Study
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11. Effects of pharmacological and genetic regulation of COMT activity in alcohol use disorder: a randomized, placebo-controlled trial of tolcapone
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12. Influence of Val108/158Met COMT Gene Polymorphism on the Efficacy of Modified Electroconvulsive Therapy in Patients with Treatment Resistant Depression
    Zhaoyu Lin, Hongbo He, Chunping Zhang, Zhijie Wang, Miaoling Jiang, Qirong Li, Xiaochang Lan, Minling Zhang, Xiong Huang · 2014 · Cell Biochemistry and Biophysics
13. Association between the COMT Val158Met polymorphism and breast cancer risk: a meta-analysis of 30,199 cases and 38,922 controls
    Xiao‐Feng He, Wu Wei, Shao-Xia Li · 2012 · Molecular Biology Reports
14. The catechol-O-methyl transferase (COMT) gene and its potential association with schizophrenia: Findings from a large German case-control and family-based sample
    Vanessa Nieratschker, Josef Frank, Thomas W. Mühleisen, Jana Strohmaier, Jens R. Wendland, J H Schumacher, Jens Treutlein, René Breuer, Rami Abou Jamra, Manuel Mattheisen et al. · 2010 · Schizophrenia Research
15. COMT Val158Met modulates subjective responses to intravenous nicotine and cognitive performance in abstinent smokers
    Aryeh I. Herman, Peter I. Jatlow, Joel E. Gelernter, Jennifer B. Listman, Mehmet Sofuoglu · 2013 · The Pharmacogenomics Journal
16. No association between catechol-o-methyltransferase Val108/158Met polymorphism and schizophrenia or its clinical symptomatology in a Mexican population
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17. Differential Effects of the Catechol-O-Methyltransferase Val158Met Genotype on the Cognitive Function of Schizophrenia Patients and Healthy Japanese Individuals
    Shoko Tsuchimine, Norio Yasui‐Furukori, Ayako Kaneda, Sunao Kaneko · 2013 · PLoS ONE
18. A functional single-nucleotide polymorphism in the catechol-O-methyltransferase gene alter vitiligo risk in a Chinese population
    Kai Li, Chunying Li, Lin Gao · 2008 · Archives of Dermatological Research
19. Common functional polymorphisms in SLC6A4 and COMT genes are associated with circadian phenotypes in a South American sample
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20. Association between genes, stressful childhood events and processing bias in depression vulnerable individuals
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21. Genetic variants in COMT and neurocognitive impairment in families of patients with schizophrenia
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22. Paroxetine influences respiration in rats: implications for the treatment of panic disorder
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23. Novel splicing and missense mutations in autosomal dominant polycystic kidney disease 1 (PKD1) gene: Expression of mutated genes
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24. Pharmacogenetics of drug-metabolizing enzymes in Italian populations
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25. Functionally gene-linked polymorphic regions and genetically controlled neurotransmitters metabolism
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26. Analysis of the monoamine oxidase A (MAOA) gene in bipolar affective disorder by association studies, meta-analyses, and sequencing of the promoter
    Robert A. Furlong, Luk W. Ho, Judy Sasha Rubinsztein, Cathy Walsh, Eugene S. Paykel, David Chaim Rubinsztein · 1999 · American Journal of Medical Genetics
27. Variation in serotonin transporter linked polymorphic region (5-HTTLPR) short/long genotype modulates resting frontal electroencephalography asymmetries in children
    Antonios I. Christou, Satoshi Endo, Yvonne Wallis, Hayley Bair, Maurice Petrus Zeegers, Joseph P. McCleery · 2015 · Development and Psychopathology
28. Membrane bound catechol-O-methytransferase is the dominant isoform for dopamine metabolism in PC12 cells and rat brain
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29. Cortical signal-to-noise ratio: insight into the pathophysiology and genetics of schizophrenia
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30. Val/Met Polymorphism of the COMT Gene Moderates the Association Between Job Strain and Early Atherosclerosis in Young Men
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31. COMT and BDNF interacted in bipolar II disorder not comorbid with anxiety disorder
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32. No Association of COMT (Val158Met) Genotype with Brain Structure Differences between Men and Women
    Anna Barnes, Matti K. Isohanni, Jennifer H. Barnett, Olli P. H. Pietiläinen, Juha M. Veijola, Jouko Miettunen, Tiina Paunio, Päivikki Tanskanen, Khanum Ridler, John Suckling A et al. · 2012 · PLoS ONE
33. Pharmacogenetics of Antipsychotic Treatment in Schizophrenia
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34. Molecular Genetics, Personality, and Internet Addiction Revisited
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35. COMT genotype and gait speed changes over ten years in older adults
    Andrea L. Metti, C. Rosano, R. Boudreau, Robyn E. Massa, K. Yaffe, S. Satterfield, T. Harris, A. Rosso · 2017 · Journal of The American Geriatrics Society
36. Sleep disturbances in Taiwanese patients with Parkinson's disease
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37. Psychological and genetic risk factors associated with suicidal behavior in Korean patients with mood disorders
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38. Optimization of 8-Hydroxyquinolines as Inhibitors of Catechol O -Methyltransferase
    Ingrid P. Buchler, Daniel Akuma, Vinh Au et al. · 2018 · Journal of Medicinal Chemistry
39. Associations between catechol-O-methyltransferase (COMT) genotypes at rs4818 and rs4680 and gene expression in human dorsolateral prefrontal cortex
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40. Role of inflammatory and pain genes polymorphisms in temporomandibular disorder and pressure pain sensitivity
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41. Voxelwise eigenvector centrality mapping of the human functional connectome reveals an influence of the catechol-O-methyltransferase val158met polymorphism on the default mode and somatomotor network
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42. Perinatal Risk Factors in the Development of Aggression and Violence
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43. Comprehensive Assessment of Genetic Variation ofCatechol-O-Methyltransferaseand Breast Cancer Risk
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44. Dynamic DNA methylation changes in the COMT gene promoter region in response to mental stress and its modulation by transcranial direct current stimulation
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45. The associations between the Val158Met in the catechol-O-methyltransferase (COMT) gene and the risk of uterine leiomyoma (ULM)
    Yi Feng, Xitong Zhao, Chunfen Zhou, Lu Yang, Yingwei Liu, Ce Bian, Jinhai Gou, Xiaojuan Lin, Zhenling Wang, Xia Zhao · 2013 · Gene
46. The COMT Val158 allele is associated with impaired delayed-match-to-sample performance in ADHD
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47. Cold-Blooded and on Purpose: A Review of the Biology of Proactive Aggression
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48. Genome-wide association study for circulating FGF21 in patients with alcohol use disorder: Molecular links between the SNHG16 locus and catecholamine metabolism
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49. Polymorphism in COMT is associated with IgG3 subclass level and susceptibility to infection in patients with chronic fatigue syndrome
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50. Ecstasy (MDMA)-induced hyponatraemia is associated with genetic variants in CYP2D6 and COMT
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51. Molecular Genetics, Personality and Internet Addiction
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52. The interaction between Comt and Bdnf variants influences obsessive–compulsive-related dysfunctional beliefs
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53. Genetic Factors, Cultural Predispositions, Happiness and Gender Equality
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54. Catechol-O-methyltransferase (COMT) genotype biases neural correlates of empathy and perceived personal distress in schizophrenia.
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55. The Genetic Studies of Obsessive-Compulsive Disorder and Its Future Directions
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56. Healthy aging increases the cognitive effects of two genes that influence extracellular dopamine.
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57. Potential link between genetic polymorphisms of catechol-O-methyltransferase and dopamine receptors and treatment efficacy of risperidone on schizophrenia
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58. Catechol-O-Methyltransferase Gene Polymorphism Is Associated with Skeletal Muscle Properties in Older Women Alone and Together with Physical Activity
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59. Possible Difference in Frequencies of Genetic Polymorphisms of Estrogen Receptor , Estrogen Metabolism and P53 Genes Between Estrogen Receptor-positive and -negative Breast Cancers
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60. The velocardiofacial syndrome in psychiatry
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61. Dissociable Catecholaminergic Modulation of Visual Attention: Differential Effects of Catechol-O-Methyltransferase and Dopamine Beta-Hydroxylase Genes on Visual Attention
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62. Placebo responses in Parkinson's disease
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63. COMT Val158Met and PPARγ Pro12Ala polymorphisms and susceptibility to Alzheimer’s disease: a meta-analysis
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64. Contributions of COMT Val158Met to cognitive stability and flexibility in infancy
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65. A potential interaction between COMT and MTHFR genetic variants in Han Chinese patients with bipolar II disorder
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66. Some dopaminergic genes polymorphisms are not associated with response to antipsychotic drugs in schizophrenic patients
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67. CYP17, Catechol-O-Methyltransferase, and Glutathione Transferase M1 Genetic Polymorphisms, Lifestyle Factors, and Breast Cancer Risk in Women on Prince Edward Island
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68. Dopaminergic denervation severity depends on COMT Val158Met polymorphism in Parkinson's disease
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69. Association of COMT Val108/158Met Genotype and Cigarette Smoking in Pregnant Women
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70. The influence of COMT rs4680 on functional connectivity in healthy adults: A systematic review
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71. The COMT val158met polymorphism in ultra-endurance athletes
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72. Catechol-O-Methyltransferase and Cytochrome P-450 1B1 Polymorphisms and Endometrial Cancer Risk
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73. Genetic Polymorphism of the Serotonin Transporter Gene, SLC6A4 rs16965628, Is Associated with Obsessive Compulsive Disorder
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74. The COMT Val158Met polymorphism and cognition in depressed and nondepressed older adults
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75. Catechol-<i>O</i>-methyltransferase Val158Met genotype moderates the effect of disorganized attachment on social development in young children
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76. Pharmacogenetic of response efficacy to antipsychotics in schizophrenia: pharmacodynamic aspects. Review and implications for clinical research
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77. Pharmacogenomics and Functional Gastrointestinal Disorders
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78. Hyperarousal, Dissociation, Emotion Dysregulation and Re-Experiencing—Towards Understanding Molecular Aspects of PTSD Symptoms
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79. The Brain Derived Neurotrophic Factor and Personality
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80. The Impact of COMT and Childhood Maltreatment on Suicidal Behaviour in Affective Disorders
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81. The Effects of Childhood Maltreatment on Non-Suicidal Self-Injury in Male Adolescents: The Moderating Roles of the Monoamine Oxidase A (MAOA) Gene and the Catechol-O-Methyltransferase (COMT) Gene
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82. O-Methylation of Catechol Estrogens by Human Placental Catechol-O-Methyltransferase: Interindividual Differences in Sensitivity to Heat Inactivation and to Inhibition by Dietary Polyphenols
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83. Drugs, genes and the blues: Pharmacogenetics of the antidepressant response from mouse to man
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84. Influence of Serotonin Transporter Genotype and Catechol-O-Methyltransferase Val158Met Polymorphism on Recognition of Emotional Faces
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85. PET neuroimaging of extrastriatal dopamine receptors and prefrontal cortex functions
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86. Association study of catechol-O-methyltransferase Val158Met polymorphism with personality traits in japanese healthy volunteers
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87. The divergent impact of COMT Val158Met on executive function in children with and without attention‐deficit/hyperactivity disorder
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88. Interaction between catechol-O-methyltransferase (COMT) Val158Met genotype and genetic vulnerability to schizophrenia during explicit processing of aversive facial stimuli
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89. Pharmacogenetics Informed Decision Making in Adolescent Psychiatric Treatment: A Clinical Case Report
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90. Association of MB-COMT polymorphisms with schizophrenia-susceptibility and symptom severity in an African cohort
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91. Translational Functional Neuroimaging in the Explanation of Depression
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92. The COMT Val158Met Polymorphism and Reaction to a Transgression: Findings of Genetic Associations in Both Chinese and German Samples
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93. The Catechol-O-Methyltransferase and Dopamine Transporter Genes Moderated the Impact of Peer Relationships on Adolescent Depressive Symptoms: A Gene–Gene–Environment Study
    Yanmiao Cao, Xiaonan Lin, Liang Chen, Linqin Ji, Wenxin Zhang · 2018 · Journal of Youth and Adolescence
94. Do AKT1, COMT and FAAH influence reports of acute cannabis intoxication experiences in patients with first episode psychosis, controls and young adult cannabis users?
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95. Association Between Monoamine Oxidase Gene Polymorphisms and Attention Deficit Hyperactivity Disorder in Korean Children
    Ho‐Jang Kwon, Han Jun Jin, Myung Ho Lim · 2014 · Genetic Testing and Molecular Biomarkers
96. Catechol-O-methyltransferase haplotypes and breast cancer among women on Long Island, New York
    Mia M. Gaudet, Jeannette T. Bensen, Jane C. Schroeder et al. · 2006 · Breast Cancer Research and Treatment
97. Val158Met Polymorphism in the Catechol-O-Methyltransferase (COMT) Gene Is Not Associated with Tardive Dyskinesia in Schizophrenia
    Seung‐Gul Kang, Jung-Eun Choi, Young-Min Park et al. · 2008 · Neuropsychobiology
98. The COMT val158met polymorphism is associated with prevalent fractures in Swedish men
    Anna L. Eriksson, Dan Mellström, Mattias Lorentzon, ERIC S. ORWOLL, Inga Redlund-Johnell, Elin Grundberg, Anna H. Holmberg, Östen Ljunggren, Magnus K. Karlsson, Claes Ohlsson · 2007 · Bone
99. The clinical use of epigenetics in psychiatry: a narrative review of epigenetic mechanisms, key candidate genes, and precision psychiatry
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100. Female with autistic disorder and monosomy X (Turner syndrome): Parent-of-origin effect of the X chromosome
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