Effects of Iron and Ascorbic Acid Supplementation on Hemoglobin Level and Work Efficiency of Anemic Women
Abstract
This study was conducted to examine the relationship between anemia, supplementation with iron and vitamin C, and productivity. Using the cyanmethemoglobin method, 671 female garment factory workers were examined. On the basis of the World Health Organization (WHO) standard, 98 were found to be mildly or moderately/severely anemic. An equal number was randomly chosen from the nonanemic workers. The subjects were then randomly assigned to either the placebo group or the group receiving 525 mg of ferrous sulfate (105 mg elemental iron) and 500 mg ascorbic acid. Only 118 of the 196 subjects completed the three-month study. The mean hemoglobin (Hb) and work output, as indicated by efficiency rating (ER), of the placebo group did not change significantly. Mildly anemic workers with supplements showed a significant improvement in mean Hb, but not in mean ER. The moderately/severely anemic group receiving supplements had significant increases in both Hb and ER.
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In trials where a proportion of participants were anaemic at enrolment, iron supplementation has previously been associated with improved maximal and submaximal exercise performance.
“In trials where a proportion of participants were anaemic at enrolment and with the knowledge that anaemia results in decreased physical capacity, iron supplementation has previously been associated with improved maximal and submaximal exercise performance.5–8”
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Bjelakovic, G., Nikolova, D., Gluud, L. L., Simonetti, R. G., & Gluud, C. (2012) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd007176.pub2 · Cited by 924 · see citing works
Daily iron supplementation for improving anaemia, iron status and health in menstruating women
Low, M. S. Y., Speedy, J., Styles, C. E., De-Regil, L. M., & Pasricha, S.-R. (2016) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd009747.pub2 · Cited by 178 · see citing works
Houston, B. L., Hurrie, D., Graham, J., Perija, B., Rimmer, E., Rabbani, R., Bernstein, C. N., Turgeon, A. F., Fergusson, D. A., Houston, D. S., et al. (2018) · BMJ Open · doi:10.1136/bmjopen-2017-019240 · Cited by 126 · see citing works
- Authors
- Florencio, C. A.
- Affiliations
- University of the Philippines System (PH)
- Corresponding author
- Florencio, Cecilia A.
- Venue
- Journal of Occupational and Environmental Medicine
- Published
- 1981-10
- Volume
- 23
- Issue
- 10
- Pages
- 699-704
- ISSN
- 1076-2752 (ISSN-L)
- OpenAlex
- W1997941564
- Cited by
- 10
- References
- 0
- Citations by year
- 2021: 1 · 2018: 1 · 2016: 1 · 2012: 2
- FWCI
- 0.00
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Occupational and Environmental Medicine (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Hematology › Iron Metabolism and Disorders
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutrition and Health Studies
- Health Sciences › Medicine › Genetics › Hemoglobinopathies and Related Disorders
- Keywords
- iron supplementation, vitamin C supplementation, anemia, hemoglobin, work efficiency, ferrous sulfate, vitamin C, women's employment, garment workers, occupational health
- MeSH terms
- Adolescent, Adult, Anemia, Ascorbic Acid, Efficiency, Employment, Female, Hemoglobins, Humans, Iron
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