Cited by 189Obstructive Sleep Apnea ResearchSleep and related disordersRespiratory Support and Mechanisms

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Compliance with continuous positive airway pressure therapy: assessing and improving treatment outcomes

Zozula, Rochelle, Rosen, Raymond·2001·Current Opinion in Pulmonary Medicine

DOI 10.1097/00063198-200111000-00005

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Abstract

Although nasal continuous positive airway pressure (CPAP) is generally effective in correcting sleep-related respiratory disturbance and associated daytime sequelae in obstructive sleep apnea syndrome (OSAS), resistance to and intolerance of CPAP poses a serious limitation to its use. Failure to comply with treatment has been reported to be as high as 25 to 50%, with patients typically abandoning therapy during the first 2 to 4 weeks of treatment. Reasons for discontinuing CPAP therapy have been primarily related to issues of mask discomfort, nasal dryness and congestion, and difficulty adapting to the pressure. Although there has been great variability in the reported rates of CPAP compliance, there have been few systematic studies to evaluate barriers to CPAP compliance or ways to improve compliance. Early identification of CPAP-related tolerance problems or barriers, psychological factors, and the predictive value of pretreatment background variables ( ie, age and gender) may enhance compliance with therapy. An important goal for OSAS management is the development of intervention strategies and educational approaches that minimize side effects and maximize patient compliance. A new classification is presented, along with suggestions and ideas for intervention.

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Authors: Zozula, R., & Rosen, R.
Affiliations: Robert Wood Johnson University Hospital (US)
Corresponding author: Zozula, Rochelle
Venue: Current Opinion in Pulmonary Medicine
Publisher: Ovid Technologies (Wolters Kluwer Health)
Published: 2001-11
Volume: 7
Issue: 6
Pages: 391-398
ISSN: 1070-5287 (ISSN-L)
DOI: 10.1097/00063198-200111000-00005
OpenAlex: W2328579826
Cited by: 189
References: 52
Citations by year: 2026: 2 · 2025: 4 · 2024: 4 · 2023: 5 · 2022: 8 · 2021: 9 · 2020: 12 · 2019: 5 · 2018: 7 · 2017: 7 · 2016: 5 · 2015: 8 · 2014: 11 · 2013: 2 · 2012: 8
FWCI: 0.66
Type: journal article
Language: en
Open access: closed
Locations: Current Opinion in Pulmonary Medicine (publishedVersion)
PubMed (publishedVersion)
Funders: National Institutes of Health (5k07hl003635-02)
National Heart, Lung, and Blood Institute (K07 HL 03635)
Topics: Health Sciences › Medicine › Physiology (medical) › Obstructive Sleep Apnea Research
Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and related disorders
Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Respiratory Support and Mechanisms
Keywords: CPAP adherence, continuous positive airway pressure, obstructive sleep apnea, CPAP intolerance, mask discomfort, nasal dryness, patient education, barriers to treatment, medication adherence, psychological factors
MeSH terms: Humans, Patient Compliance, Patient Education as Topic, Positive-Pressure Respiration, Sleep Apnea Syndromes, Treatment Refusal, Treatment Outcome

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Compliance with continuous positive airway pressure therapy: assessing and improving treatment outcomes

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