CoChat
Sign Up
Cited by 141Intensive Care Unit Cognitive DisordersAnesthesia and Sedative AgentsNosocomial Infections in ICU

The DOI matches its Crossref record; 29 of the 29 references it cites were found in a registry or an index.

Delirium as detected by the CAM-ICU predicts restraint use among mechanically ventilated medical patients*

Micek, Scott T., Anand, Nitin J., Laible, Brad R., Shannon, William D., Kollef, Marin H.·2005·Critical Care Medicine
DOI 10.1097/01.ccm.0000164540.58515.bf
Open this paper in CoChat — free account

Abstract

OBJECTIVE: The first goal of this investigation was to identify individuals with delirium defined by the Confusion Assessment Method for the Intensive Care Unit (CAM-ICU) among medical patients with respiratory failure. Our second goal was to compare clinical interventions including use of continuous sedation infusions, the number of ventilator-free days, ICU length of stay, hospital mortality, and use of physical restraints in mechanically ventilated patients with and without delirium. DESIGN: A prospective, single-center, observational cohort study. SETTING: The medical intensive care unit (19 beds) of an urban teaching hospital. PATIENTS: Adult, intubated, and mechanically ventilated patients. INTERVENTIONS: Daily evaluation with the CAM-ICU, outcomes assessment, and prospective data collection. MEASUREMENTS AND MAIN RESULTS: Among 93 patients evaluated using the CAM-ICU, 44 patients (47%) developed delirium (CAM-ICU+) for >/=1 day while in the intensive care unit. Twenty-two patients (24%) had no episodes of delirium recorded (CAM-ICU-), and 27 (29%) remained comatose until extubation or death. A statistically greater number of patients with delirium (CAM-ICU+) received continuous infusions of midazolam (59% vs. 32%, p < .05) or fentanyl (57% vs. 32%, p < .05) and physical soft-limb restraints (77% vs. 50%, p < .05) compared with patients without delirium (CAM-ICU-). CONCLUSIONS: The identification of delirium using the CAM-ICU was associated with greater use of continuous sedation infusions and physical restraints. Additional studies are required to determine how the use of these specific interventions influences the occurrence and the natural history of delirium among critically ill patients.

Overview

Integrity signals

Registry

Crossref · 10.1097/01.ccm.0000164540.58515.bf

Cites

29 of 29 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Verification

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Citations

Cites

Show all 29 references

Research works printed but not linked: 1

  1. Dolan, 2001, J Gerontol Med Sci, 55A, M527

Cited by

Sorted by citations

Items 101–139 of 139

Related

See all

Metadata

Authors
Micek, S. T., Anand, N. J., Laible, B. R., Shannon, W. D., & Kollef, M. H.
Affiliations
Barnes-Jewish Hospital (US)
ORCID
Kollef, Marin H.
Venue
Critical Care Medicine
Publisher
Ovid Technologies (Wolters Kluwer Health)
Published
2005-06
Volume
33
Issue
6
Pages
1260-1265
ISSN
0090-3493 (ISSN-L)
DOI
10.1097/01.ccm.0000164540.58515.bf
OpenAlex
W2145882151
Cited by
141
References
29
Citations by year
2026: 1 · 2025: 5 · 2024: 1 · 2022: 5 · 2021: 12 · 2020: 6 · 2019: 6 · 2018: 10 · 2017: 5 · 2016: 9 · 2015: 7 · 2014: 11 · 2013: 10 · 2012: 15
FWCI
4.67
Type
journal article
Language
en
Open access
closed
Locations
  • Critical Care Medicine (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Critical Care and Intensive Care Medicine › Intensive Care Unit Cognitive Disorders
  • Health Sciences › Medicine › Anesthesiology and Pain Medicine › Anesthesia and Sedative Agents
  • Health Sciences › Medicine › Critical Care and Intensive Care Medicine › Nosocomial Infections in ICU
Keywords
delirium, CAM-ICU, physical restraint, mechanical ventilation, medical intensive care unit, continuous sedation, midazolam, fentanyl, respiratory failure, ventilator-free days, ICU length of stay, in-hospital mortality, comatose patients
MeSH terms
Adult, Aged, Analgesics, Opioid, Delirium, Female, Fentanyl, Humans, Hypnotics and Sedatives, Length of Stay, Male, Midazolam, Middle Aged, Missouri, Prospective Studies, Psychiatric Status Rating Scales, Respiration, Artificial, Restraint, Physical, Incidence, Hospital Mortality

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review