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Cited by 870

The DOI matches its Crossref record; 18 of the 18 references it cites were found in a registry or an index.

Physicochemical Basis of the Biologic Properties of Mineral Trioxide Aggregate

SARKAR, N, CAICEDO, R, RITWIK, P, MOISEYEVA, R, KAWASHIMA, I·2005·Journal of Endodontics
DOI 10.1097/01.don.0000133155.04468.41
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Abstract

This study characterized the interactions of mineral trioxide aggregate with a synthetic tissue fluid composed of a neutral phosphate buffer saline solution and root canal dentin in extracted human teeth using inductively coupled plasma-atomic emission spectroscopy, scanning electron microscopy, energy dispersive X-ray analysis, and X-ray diffraction. Mineral trioxide aggregate exposed to synthetic tissue fluid at 37 degrees C released its metallic constituents and produced precipitates with a composition and structure similar to that of hydroxyapatite [Ca10(PO4)6(OH)2-HA]. Endodontically prepared teeth filled with mineral trioxide aggregate and stored in synthetic tissue fluid at 37 degrees C for 2 months produced at the dentin wall an adherent interfacial layer that resembled hydroxyapatite in composition. The authors conclude that Ca, the dominant ion released from mineral trioxide aggregate, reacts with phosphates in synthetic tissue fluid, yielding hydroxyapatite. The dentin-mineral trioxide aggregate interfacial layer results from a similar reaction. The sealing ability, biocompatibility, and dentinogenic activity of mineral trioxide aggregate is attributed to these physicochemical reactions.

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Metadata

Authors
SARKAR, N., CAICEDO, R., RITWIK, P., MOISEYEVA, R., & KAWASHIMA, I.
Venue
Journal of Endodontics
Publisher
Ovid Technologies (Wolters Kluwer Health)
Published
2005-02
Volume
31
Issue
2
Pages
97-100
ISSN
0099-2399 (ISSN-L)
DOI
10.1097/01.don.0000133155.04468.41
OpenAlex
W1966824111
Cited by
870
References
18
FWCI
27.77
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Physicochemical Basis of the Biologic Properties of Mineral Trioxide Aggregate. https://app.cochat.ai/papers/10.1097/01.don.0000133155.04468.41
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SARKAR, N., CAICEDO, R., RITWIK, P., MOISEYEVA, R., & KAWASHIMA, I. (2005). Physicochemical Basis of the Biologic Properties of Mineral Trioxide Aggregate. Journal of Endodontics. https://doi.org/10.1097/01.don.0000133155.04468.41

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.