Cited by 350Pain Management and Placebo EffectPain Mechanisms and TreatmentsPain Management and Treatment

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Nocebo hyperalgesia: how anxiety is turned into pain

Colloca, Luana, Benedetti, Fabrizio·2007·Current Opinion in Anaesthesiology

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Abstract

PURPOSE OF REVIEW: Nocebo hyperalgesia is a phenomenon that is opposite to placebo analgesia and whereby expectation of pain increase plays a crucial role. In recent times, both the neuroanatomical and the neurochemical bases of the nocebo effect and of nocebo-related effects have begun to be explored. Here, we highlight recent advances in our understanding of the neurobiology of the nocebo hyperalgesic effect. RECENT FINDINGS: A typical nocebo hyperalgesic response occurs following the administration of an inert substance which the subject believes to be a hyperalgesic agent (negative placebo or nocebo). It has been shown that the subject's negative expectations of pain worsening induce anticipatory anxiety about the impending pain increase and this triggers the activation of cholecystokinin that, in turn, facilitates pain transmission. Accordingly, cholecystokinin antagonists have been found to prevent this anxiety-induced hyperalgesia. Brain-imaging studies have shown that the perceived intensity of a painful stimulus following negative expectations of pain increase is higher than in the absence of negative expectations and this is associated with changes in activation of specific brain regions. SUMMARY: Since pain appears to be amplified by anxiety through the activation of cholecystokininergic systems, new therapeutic strategies, such as new cholecystokinin antagonists, can be envisaged whenever pain has an important anxiety component.

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Fear-avoidance and its consequences in chronic musculoskeletal pain: a state of the art.
Vlaeyen, J. W. S., & Linton, S. J. (2000) · Pain · doi:10.1016/s0304-3959(99)00242-0 · Cited by 4,931
The fear-avoidance model of musculoskeletal pain: Current state of scientific evidence
Leeuw, M., Goossens, M. E. J. B., Linton, S. J., Crombez, G., Boersma, K., & Vlaeyen, J. W. S. (2007) · Journal of Behavioral Medicine · doi:10.1007/s10865-006-9085-0 · Cited by 2,261
Placebo-Induced Changes in fMRI in the Anticipation and Experience of Pain
Wager, T. D., Rilling, J. K., Smith, E. E., Sokolik, A., Casey, K. L., Davidson, R. J., Kosslyn, S. M., Rose, R. M., & Cohen, J. D. (2004) · Science · doi:10.1126/science.1093065 · Cited by 1,992
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Dissociating pain from its anticipation in the human brain
Ploghaus, A., Tracey, I., Gati, J. S., Clare, S., Menon, R. S., Matthews, P. M., & Rawlins, J. N. P. (1999) · Science · doi:10.1126/science.284.5422.1979 · Cited by 1,151
THE MECHANISM OF PLACEBO ANALGESIA
Levine, J., Gordon, N., & Fields, H. (1978) · The Lancet · doi:10.1016/s0140-6736(78)92762-9 · Cited by 1,094
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Neurobiological Mechanisms of the Placebo Effect
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Kennedy, 1961, The nocebo reaction, Med World, 95, 203

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Authors: Colloca, L., & Benedetti, F.
Affiliations: University of Turin (IT)
Corresponding author: Benedetti, Fabrizio
ORCID: Colloca, Luana
Benedetti, Fabrizio
Venue: Current Opinion in Anaesthesiology
Publisher: Ovid Technologies (Wolters Kluwer Health)
Published: 2007-10
Volume: 20
Issue: 5
Pages: 435-439
ISSN: 0952-7907 (ISSN-L)
DOI: 10.1097/aco.0b013e3282b972fb
OpenAlex: W2028713040
Cited by: 350
References: 51
Citations by year: 2026: 9 · 2025: 12 · 2024: 18 · 2023: 12 · 2022: 28 · 2021: 17 · 2020: 65 · 2019: 27 · 2018: 12 · 2017: 15 · 2016: 18 · 2015: 16 · 2014: 21 · 2013: 22 · 2012: 14
FWCI: 0.71
Type: journal article
Language: en
Open access: closed
Locations: Current Opinion in Anaesthesiology (publishedVersion)
PubMed (publishedVersion)
Funders: Regione Piemonte
Topics: Life Sciences › Neuroscience › Cognitive Neuroscience › Pain Management and Placebo Effect
Health Sciences › Medicine › Physiology (medical) › Pain Mechanisms and Treatments
Health Sciences › Medicine › Anesthesiology and Pain Medicine › Pain Management and Treatment
Keywords: nocebo hyperalgesia, anxiety, pain anticipation, cholecystokinin, cholecystokinin antagonists, placebo analgesia, anticipatory anxiety, pain perception, brain activation, neurobiology of pain
MeSH terms: Animals, Anxiety, Cholecystokinin, Humans, Hyperalgesia, Placebo Effect, Rats

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Nocebo hyperalgesia: how anxiety is turned into pain

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