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Cited by 178

The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.

Mesenchymal stem cells for acute lung injury: Preclinical evidence

Open access
Matthay, Michael A., Goolaerts, Arnaud, Howard, James P., Woo Lee, Jae·2010·Critical Care Medicine

Abstract

Several experimental studies have suggested that mesenchymal stem cells may have value for the treatment of clinical disorders, including myocardial infarction, diabetes, acute renal failure, sepsis, and acute lung injury. In preclinical studies, mesenchymal stem cells have been effective in reducing lung injury from endotoxin, live bacteria, bleomycin, and hyperoxia. In some studies, the cultured medium from mesenchymal stem cells has been as effective as the mesenchymal stem cells themselves. Several paracrine mediators that can mediate the effect of mesenchymal stem cells have been identified, including interleukin-10, interleukin-1ra, keratinocyte growth factor, and prostaglandin E2. Further preclinical studies are needed, as is planning for clinical trials for acute lung injury.

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Integrity signals

Registry

Crossref · 10.1097/ccm.0b013e3181f1ff1d

Cites

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Metadata

Authors
Matthay, M. A., Goolaerts, A., Howard, J. P., & Woo Lee, J.
Venue
Critical Care Medicine
Published
2010-10
Volume
38
Issue
10 Suppl
Pages
S569-S573
ISSN
0090-3493 (ISSN-L)
OpenAlex
W2072386858
Cited by
178
References
3
FWCI
4.54
Type
journal article
Language
en
Open access
green

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This page
CoChat. (2026). Citation check: Mesenchymal stem cells for acute lung injury: Preclinical evidence. https://app.cochat.ai/papers/10.1097/ccm.0b013e3181f1ff1d
The paper
Matthay, M. A., Goolaerts, A., Howard, J. P., & Woo Lee, J. (2010). Mesenchymal stem cells for acute lung injury: Preclinical evidence. Critical Care Medicine. https://doi.org/10.1097/ccm.0b013e3181f1ff1d

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.