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Improvement in Aerobic Capacity After an Exercise Program in Sporadic Inclusion Body Myositis

Johnson, Liam G, Collier, Kelly E, Edwards, Dylan J, Philippe, Danielle L, Eastwood, Peter R, Walters, Susan E, Thickbroom, Gary W, Mastaglia, Frank L·2009·Journal of Clinical Neuromuscular Disease

Abstract

Objectives: The study aimed to investigate the effects of a combined functional and aerobic exercise program on aerobic capacity, muscle strength, and functional mobility in a group of patients with sporadic inclusion body myositis (IBM). Methods: Aerobic capacity, muscle strength, and functional capacity assessments were conducted on 7 participants with sporadic IBM before and after a 12-week exercise program, which included resistance exercises and aerobic stationary cycling 3 times per week on alternative days. Results: Aerobic capacity of the group increased significantly by 38%, and significant strength improvements were observed in 4 of the muscle groups tested ( P < 0.05). The exercise program was well tolerated, and there was no significant change in the serum creatine kinase level after the exercise period. Conclusions: An aerobic exercise program can be safely tolerated by patients with sporadic IBM and can improve aerobic capacity and muscle strength when combined with resistance training. These findings indicate that aerobic and functional muscle strengthening exercise should be considered in the management of patients with IBM.

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Research works printed but not linked: 29

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Cited by

Metadata

Authors
Johnson, L. G., Collier, K. E., Edwards, D. J., Philippe, D. L., Eastwood, P. R., Walters, S. E., Thickbroom, G. W., & Mastaglia, F. L.
Venue
Journal of Clinical Neuromuscular Disease
Published
2009-06
Volume
10
Issue
4
Pages
178-184
ISSN
1522-0443
Cited by
87
References
0
Language
en

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