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Cited by 320

The DOI matches its Crossref record; 126 of the 126 references it cites were found in a registry or an index.

Depression and Cardiac Disease: A Review

Celano, Christopher M., Huffman, Jeff C.·2011·Cardiology in Review

Abstract

Depression is highly prevalent in cardiac patients, with 20% to 40% of patients meeting criteria for major depressive disorder or experiencing an elevation in depressive symptoms. These depressive symptoms are often chronic and persistent, and they have been associated with the development and progression of coronary artery disease, worse health-related quality of life, poor physical functioning, recurrent cardiac events, and a 2- to 2.5-fold increased risk of mortality. Impaired adherence to health behaviors and adverse physiological effects of depression, including inflammation, endothelial dysfunction, platelet hyperactivity, and autonomic nervous system abnormalities, may link depression with adverse cardiac outcomes. Pharmacologic and psychotherapeutic interventions appear to be safe and effective at reducing depressive symptoms in patients with cardiovascular disease and may impact cardiac outcomes. Unfortunately, depression often is unrecognized and untreated in this population, despite the availability of brief screening tools that can be used for this purpose. We recommend the routine screening of cardiac patients for depression when there are adequate mechanisms for management and referral, such as available consulting psychiatrists or care management programs that facilitate the delivery of pharmacologic and psychotherapeutic treatments in this vulnerable population.

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Metadata

Authors
Celano, C. M., & Huffman, J. C.
Venue
Cardiology in Review
Published
2011-05
Volume
19
Issue
3
Pages
130-142
ISSN
1061-5377 (ISSN-L)
OpenAlex
W2045542163
Cited by
320
References
126
FWCI
13.95
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Depression and Cardiac Disease: A Review. https://app.cochat.ai/papers/10.1097/crd.0b013e31820e8106
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Celano, C. M., & Huffman, J. C. (2011). Depression and Cardiac Disease: A Review. Cardiology in Review. https://doi.org/10.1097/crd.0b013e31820e8106

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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