The DOI matches its Crossref record; 16 of the 16 references it cites were found in a registry or an index.
Laughter-Induced Syncope
Abstract
Reported cases of syncope caused directly by laughter are rare. The common scenario described in a few reports involved episodes of fortuitous laughter, sometimes followed by a short prodrome of lightheadedness, facial flushing, and dizziness, followed by an episode of definite syncope. There were no seizure-like movements, automatisms, or bladder or bowel incontinence. After the syncopal episodes that were seconds in length, the patients regained consciousness, and at that point were fully oriented. These episodes could recur in a similar situation with such laughter. Many of these patients subsequently underwent full syncope workups, without elucidating a primary cardiac or neurologic cause. In this review of laughter-induced syncope, we describe a patient of ours who fit these descriptions. This phenomenon is likely a subtype of benign Valsalva-related syncope, with autonomic reflex arcs coming into play that ultimately result in global cerebral hypoperfusion. Besides the Valsalva produced by a great fit of laughter, laughter itself has its own neuroendocrine and vasculature effects that may play a role.
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“In contrast, a pronounced BP fall beyond what is normally expected during forced expiration, but a normal chronotropic response during the manoeuvre, may occur in patients with suspected situational syncope, i.e. syncope occurring during some forms of situational syncope, e.g. coughing, brass instrument playing, singing, and weightlifting. 144”
From 2018 ESC Guidelines for the diagnosis and management of syncope (2018) · cites this paper as [144]
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Cites
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Research works printed but not linked: 1
- Black, 1984, Laughter., JAMA, 252, 2995, 10.1001/jama.1984.03350210043027 · DOI
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2018 ESC Guidelines for the diagnosis and management of syncope
Brignole, M., Moya, A., de Lange, F. J., Deharo, J.-C., Elliott, P. M., Fanciulli, A., Fedorowski, A., Furlan, R., Kenny, R. A., Martín, A., et al. (2018) · European Heart Journal · doi:10.1093/eurheartj/ehy037 · Cited by 1,951
2018 ESC Guidelines for the diagnosis and management of syncope
Brignole, M., Moya‐Mitjans, À., de Lange, F. J., Deharo, J., Elliot, P. M., Fanciulli, A., Fedorowski, A., Furlan, R., Kenny, R. A., Martiın, A., et al. (2018) · Kardiologia Polska · doi:10.5603/kp.2018.0161 · Cited by 475
Practical Instructions for the 2018 ESC Guidelines for the diagnosis and management of syncope
Brignole, M., Moya‐Mitjans, À., de Lange, F. J., Deharo, J., Elliot, P. M., Fanciulli, A., Fedorowski, A., Furlan, R., Kenny, R. A., Martín, A., et al. (2018) · European Heart Journal · doi:10.1093/eurheartj/ehy071 · Cited by 247
Cheshire, W. P. (2017) · CONTINUUM Lifelong Learning in Neurology · doi:10.1212/con.0000000000000444 · Cited by 25
Epilepsy and cataplexy in Angelman syndrome. Genotype-phenotype correlations
Mertz, L. G. B., Christensen, R., Vogel, I., Hertz, J. M., & Østergaard, J. R. (2016) · Research in Developmental Disabilities · doi:10.1016/j.ridd.2016.06.002 · Cited by 13
Metadata
- Authors
- Kim, A. J., & Frishman, W. H.
- Affiliations
- Westchester Medical Center (US)
- Corresponding author
- Frishman, William H.
- Venue
- Cardiology in Review
- Published
- 2012-07
- Volume
- 20
- Issue
- 4
- Pages
- 194-196
- ISSN
- 1061-5377 (ISSN-L)
- OpenAlex
- W2064135856
- Cited by
- 13
- References
- 16
- Citations by year
- 2025: 1 · 2024: 1 · 2021: 2 · 2018: 3 · 2017: 2 · 2016: 2 · 2015: 2
- FWCI
- 0.65
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Cardiology in Review (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Syncope and Autonomic Disorders
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Rate Variability and Autonomic Control
- Health Sciences › Medicine › Clinical Neurology › Neurological and metabolic disorders
- Keywords
- autonomic reflexes, cerebral hypoperfusion, lightheadedness, dizziness
- MeSH terms
- Aged, Humans, Laughter, Male, Middle Aged, Pressure, Syncope, Vasodilation, Baroreflex
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