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Mobile Phone Use and Incidence of Glioma in the Nordic Countries 1979–2008: Consistency Check
Abstract
Background Some case-control studies have reported increased risks of glioma associated with mobile phone use. If true, this would ultimately affect the time trends for incidence rates (IRs). Correspondingly, lack of change in IRs would exclude certain magnitudes of risk. We investigated glioma IR trends in the Nordic countries, and compared the observed with expected incidence rates under various risk scenarios. Methods We analyzed annual age-standardized incidence rates in men and women aged 20 to 79 years during 1979-2008 using joinpoint regression (35,250 glioma cases). Probabilities of detecting various levels of relative risk were computed using simulations. Results For the period 1979 through 2008, the annual percent change in incidence rates was 0.4% (95% confidence interval = 0.1% to 0.6%) among men and 0.3% (0.1% to 0.5%) among women. Incidence rates have decreased in young men (20-39 years) since 1987, remained stable in middle-aged men (40-59 years) throughout the 30-year study period, and increased slightly in older men (60-79 years). In simulations, assumed relative risks for all users of 2.0 for an induction time of up to 15 years, 1.5 for up to 10 years, and 1.2 for up to 5 years were incompatible with observed incidence time trends. For heavy users of mobile phones, risks of 2.0 for up to 5 years' induction were also incompatible. Conclusion No clear trend change in glioma incidence rates was observed. Several of the risk increases seen in case-control studie…
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“Such effect sizes have been shown to be incompatible with the actual incidence time trends of glioma in three simulation studies (Deltour et al., 2012; Deltour et al., 2022; Little et al., 2012).”
From The effect of exposure to radiofrequency fields on cancer risk in the general and working population: A systematic review of human observational studies - Part I: Most researched outcomes. (2024) · cites this paper as Deltour et al., 2012
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Karipidis, K., Baaken, D., Loney, T., Blettner, M., Brzozek, C., Elwood, M., Narh, C., Orsini, N., Röösli, M., Paulo, M. S., et al. (2024) · Environment International · doi:10.1016/j.envint.2024.108983 · Cited by 58
Metadata
- Authors
- Deltour, I., Auvinen, A., Feychting, M., Johansen, C., Klaeboe, L., Sankila, R., & Schüz, J.
- Venue
- Epidemiology
- Published
- 2012-03
- Volume
- 23
- Issue
- 2
- Pages
- 301-307
- ISSN
- 1044-3983
- Cited by
- 105
- References
- 0
- Language
- en
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- Deltour, I., Auvinen, A., Feychting, M., Johansen, C., Klaeboe, L., Sankila, R., & Schüz, J. (2012). Mobile Phone Use and Incidence of Glioma in the Nordic Countries 1979–2008: Consistency Check. Epidemiology. https://doi.org/10.1097/ede.0b013e3182448295