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Cited by 274Sperm and Testicular FunctionMale Reproductive Health StudiesReproductive Health and Technologies

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Diagnosis and Treatment of Infertility in Men: AUA/ASRM Guideline Part I

Schlegel, Peter N., Sigman, Mark, Collura, Barbara, De Jonge, Christopher J., Eisenberg, Michael L., Lamb, Dolores J., Mulhall, John P., Niederberger, Craig, Sandlow, Jay I., Sokol, Rebecca Z., Spandorfer, Steven D., Tanrikut, Cigdem, Treadwell, Jonathan R., Oristaglio, Jeffrey T., Zini, Armand·2021·Journal of Urology
DOI 10.1097/ju.0000000000001521
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Abstract

PURPOSE: The summary presented herein represents Part I of the two-part series dedicated to the Diagnosis and Treatment of Infertility in Men: AUA/ASRM Guideline. Part I outlines the appropriate evaluation of the male in an infertile couple. Recommendations proceed from obtaining an appropriate history and physical exam (Appendix I), as well as diagnostic testing, where indicated. MATERIALS/METHODS: The Emergency Care Research Institute Evidence-based Practice Center team searched PubMed®, Embase®, and Medline from January, 2000 through May, 2019. When sufficient evidence existed, the body of evidence was assigned a strength rating of A (high), B (moderate), or C (low) for support of Strong, Moderate, or Conditional Recommendations. In the absence of sufficient evidence, additional information is provided as Clinical Principles and Expert Opinions (table 1[Table: see text]). This summary is being simultaneously published in Fertility and Sterility and The Journal of Urology. RESULTS: This Guideline provides updated, evidence-based recommendations regarding evaluation of male infertility as well as the association of male infertility with other important health conditions. The detection of male infertility increases the risk of subsequent development of health problems for men. In addition, specific medical conditions are associated with some causes for male infertility. Evaluation and treatment recommendations are summarized in the associated algorithm (figure[Figure: see text]). CONCLUSION: The presence of male infertility is crucial to the health of patients and its effects must be considered for the welfare of society. This document will undergo updating as the knowledge regarding current treatments and future treatment options continues to expand.

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Metadata

Authors
Schlegel, P. N., Sigman, M., Collura, B., De Jonge, C. J., Eisenberg, M. L., Lamb, D. J., Mulhall, J. P., Niederberger, C., Sandlow, J. I., Sokol, R. Z., Spandorfer, S. D., Tanrikut, C., Treadwell, J. R., Oristaglio, J. T., & Zini, A.
Affiliations
  • NewYork–Presbyterian Hospital (US)
  • Brown University (US)
  • ReSoLVE Center of Excellence (FI)
  • University of Minnesota School of Medicine
  • Stanford Medicine (US)
  • Weill Cornell Medicine (US)
  • Memorial Sloan Kettering Cancer Center (US)
  • University of Illinois Chicago (US)
  • University of Southern California (US)
  • Georgetown University (US)
  • ECRI Institute (US)
  • McGill University (CA)
ORCID
Venue
Journal of Urology
Publisher
Ovid Technologies (Wolters Kluwer Health)
Published
2021-01
Volume
205
Issue
1
Pages
36-43
ISSN
  • 0022-5347 (ISSN-L)
  • 1527-3792
DOI
10.1097/ju.0000000000001521
OpenAlex
W4254230981
Cited by
274
References
0
Citations by year
2026: 53 · 2025: 51 · 2024: 67 · 2023: 43 · 2022: 39 · 2021: 21
FWCI
18.64
Type
journal article
Language
en
Open access
closed
Locations
  • The Journal of Urology (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Reproductive Medicine › Sperm and Testicular Function
  • Health Sciences › Medicine › Urology › Male Reproductive Health Studies
  • Health Sciences › Medicine › Reproductive Medicine › Reproductive Health and Technologies
Keywords
male infertility, infertility evaluation, infertility diagnosis, infertility treatment, clinical guidelines, diagnostic testing, history and physical examination
MeSH terms
Counseling, Humans, Infertility, Male, Life Style, Male, Scrotum, Societies, Medical, Ultrasonography, United States, Urology, Reproductive Medicine, Evidence-Based Medicine, Semen Analysis

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