Prognostic model for predicting hearing recovery in idiopathic sudden sensorineural hearing loss
Abstract
Hypothesis To aid in realistic counseling of patients at the time of their first visit concerning their chances for recovery, we created a simple prognostic model for predicting hearing recovery in idiopathic sudden sensorineural hearing loss (ISSHL). Background An important element of research on ISSHL is to identify prognostic factors for this disease. Many studies have described predictive indicators to identify patients with a good prognosis needing no or minimal treatment. Only a few of these studies have included a model for calculating the probability for patient recovery, which may be important for clinical work, but these prognostic tables have not achieved widespread use clinically. Methods Evaluation of an electronic patient data base of 541 patients with ISSHL. The standard treatment was carbogen inhalation (95% O2 and 5% CO2 8 times per day in duration of 30 min) and prednisone orally (100 mg in 1 morning dose) for 7 days. Factors that were analyzed included the patient's age, the interval between the onset of symptoms and beginning of treatment, the presence or absence of vertigo and tinnitus, audiometric patterns, the severity of hearing loss, and hearing in the opposite ear. Hearing gain was expressed either as absolute hearing gain or as relative hearing gain. Significant recovery of hearing was defined as the final pure-tone audiometry of 30 dB or less (or the same as the pure-tone audiometry of the opposite ear). Results The absolute hearing gain was 15.1 d…
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Few studies have analyzed the clinical features and prognostic factors associated with recurrent ISSNHL.
“Although many studies have assessed the causes, pathogenesis, diagnostic criteria, treatment, and prognostic factors of ISSNHL [10-12], few have analyzed the clinical features and prognostic factors associated with recurrent ISSNHL.”
From Prognostic Factors Associated with Recovery from Recurrent Idiopathic Sudden Sensorineural Hearing Loss: Retrospective Analysis and Systematic Review (2022) · cites this paper as [11]
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Clinical Practice Guideline: Sudden Hearing Loss (Update)
Chandrasekhar, S. S., Tsai Do, B. S., Schwartz, S. R., Bontempo, L. J., Faucett, E. A., Finestone, S. A., Hollingsworth, D. B., Kelley, D. M., Kmucha, S. T., Moonis, G., et al. (2019) · Otolaryngology–Head and Neck Surgery · doi:10.1177/0194599819859885 · Cited by 931 · see citing works
Clinical Analysis of Recurrent Sudden Sensorineural Hearing Loss
Park, I.-S., Kim, Y. B., Choi, S. H., & Hong, S. M. (2013) · ORL · doi:10.1159/000353552 · Cited by 23 · see citing works
Jeon, S. Y., Kang, D. W., Kim, S. H., Byun, J. Y., & Yeo, S. G. (2022) · Journal of Clinical Medicine · doi:10.3390/jcm11051453 · Cited by 9 · see citing works
- Authors
- Čvorović, L., Đeric, D., Probst, R., & Hegemann, S.
- Affiliations
- Zemun Hospital (RS)
- University Hospital Zurich (CH)
- Corresponding author
- Čvorović, Ljiljana
- Venue
- Otology & Neurotology
- Published
- 2008-06
- Volume
- 29
- Issue
- 4
- Pages
- 464-469
- ISSN
- 1531-7129 (ISSN-L)
- OpenAlex
- W2061118057
- Cited by
- 178
- References
- 0
- Citations by year
- 2026: 6 · 2025: 10 · 2024: 29 · 2023: 12 · 2022: 9 · 2021: 12 · 2020: 10 · 2019: 6 · 2018: 5 · 2017: 13 · 2016: 8 · 2015: 9 · 2014: 9 · 2013: 8 · 2012: 7
- FWCI
- 5.46
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Otology & Neurotology (publishedVersion)
- PubMed (publishedVersion)
- Zurich Open Repository and Archive (University of Zurich) (submittedVersion)
- Topics
- Life Sciences › Neuroscience › Neurology › Vestibular and auditory disorders
- Life Sciences › Neuroscience › Sensory Systems › Hearing, Cochlea, Tinnitus, Genetics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Hearing Loss and Rehabilitation
- Keywords
- idiopathic sudden sensorineural hearing loss, hearing recovery, prognostic model, vertigo, time to treatment, contralateral hearing, carbogen inhalation, prednisone, pure tone audiometry, patient counseling, prognostic factors, tinnitus
- MeSH terms
- Adolescent, Adult, Aged, Aged, 80 and over, Algorithms, Anti-Inflammatory Agents, Audiometry, Pure-Tone, Carbon Dioxide, Hearing Loss, Sudden, Female, Humans, Male, Middle Aged, Oxygen, Predictive Value of Tests, Prednisone, Prognosis, Retrospective Studies, Tinnitus, Vertigo, Models, Statistical, Treatment Outcome
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