Risk of Developing Sudden Sensorineural Hearing Loss in Diabetic Patients: A Population-Based Cohort Study
Abstract
Objectives To explore the risk of development of sudden sensorineural hearing loss (SSHL) among diabetes mellitus patients. Study design A retrospective cohort study. Setting Population-based study of Taiwan National Health Insurance Research Database. Patients Approximately 26,556 newly diagnosed diabetic patients and 26,556 comparison subjects without diabetes mellitus were selected from claims made during 2000 to 2004. Main outcome measures The incidence of sudden sensorineural hearing loss (SSHL) at the end of 2009 was determined. Results The incidence of SSHL was 1.54-fold higher in the diabetic group compared with the nondiabetic group (1.29 versus 0.78 per 1,000 person-years), and using Cox proportional hazard regressions, the adjusted hazard ratio (HR) was 1.592 (95% confidence interval [CI], 1.295-1.957). The risk of developing SSHL increased substantially to an HR of 2.060 (95% CI, 1.051-4.037), for patients who required triple antidiabetic medication compared with diabetic patients treated with a single antidiabetic drug. An increased risk of developing SSHL, with adjusted HRs of 1.574 (95% CI, 1.091-2.271) and 2.842 (95% CI, 1.880-4.295), was observed in diabetic patients with newly diagnosed comorbidities of retinopathy or retinopathy combined with renal insufficiency, which are both expected to reflect the severity of diabetes. Conclusion Diabetes mellitus was significantly associated with an increased risk of developing SSHL. Coronary heart disease or retinopat…
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Several studies have reported an association between ISSNHL and DM.
“Several studies have reported an association between ISSNHL and DM [25-29]”
From Prognostic Factors Associated with Recovery from Recurrent Idiopathic Sudden Sensorineural Hearing Loss: Retrospective Analysis and Systematic Review (2022) · cites this paper as [27]
ISSNHL has been reported to be associated with a history of hypertension, chronic kidney disease, diabetes mellitus, hypercholesterolemia, and stroke.
“ISSNHL has been reported to be associated with a history of hypertension (HTN), chronic kidney disease, diabetes mellitus (DM), hypercholesterolemia, and stroke [25-29].”
From Prognostic Factors Associated with Recovery from Recurrent Idiopathic Sudden Sensorineural Hearing Loss: Retrospective Analysis and Systematic Review (2022) · cites this paper as [27]
Cited by
Sorted by citations
Jeon, S. Y., Kang, D. W., Kim, S. H., Byun, J. Y., & Yeo, S. G. (2022) · Journal of Clinical Medicine · doi:10.3390/jcm11051453 · Cited by 9 · see citing works
- Authors
- Lin, S.-W., Lin, Y.-S., Weng, S.-F., & Chou, C.-W.
- Affiliations
- University of British Columbia (CA)
- Chi Mei Medical Center (TW)
- Chia Nan University of Pharmacy and Science (TW)
- Corresponding author
- Lin, Shih-Wei
- Venue
- Otology & Neurotology
- Published
- 2012-12
- Volume
- 33
- Issue
- 9
- Pages
- 1482-1488
- ISSN
- 1531-7129 (ISSN-L)
- OpenAlex
- W1971468581
- Cited by
- 87
- References
- 0
- Citations by year
- 2026: 7 · 2025: 3 · 2024: 7 · 2023: 12 · 2022: 7 · 2021: 4 · 2020: 8 · 2019: 10 · 2018: 3 · 2017: 3 · 2016: 6 · 2015: 9 · 2014: 5 · 2013: 3
- FWCI
- 2.73
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Otology & Neurotology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Neurology › Vestibular and auditory disorders
- Life Sciences › Neuroscience › Sensory Systems › Hearing, Cochlea, Tinnitus, Genetics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Hearing Loss and Rehabilitation
- Keywords
- sudden sensorineural hearing loss, diabetes mellitus, diabetic patients, antidiabetic drugs, diabetic retinopathy, renal failure, coronary artery disease, diabetes severity, incidence, risk factors
- MeSH terms
- Adolescent, Adult, Aged, Aged, 80 and over, Child, Child, Preschool, Hearing Loss, Sudden, Diabetic Angiopathies, Diabetic Nephropathies, Diabetic Retinopathy, Female, Hearing Loss, Sensorineural, Humans, Hypoglycemic Agents, Infant, Infant, Newborn, Male, Middle Aged, Population, Retrospective Studies, Risk, Taiwan, Cohort Studies, Comorbidity, Proportional Hazards Models, Diabetes Complications, Young Adult
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
