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Cited by 481

The DOI matches its Crossref record; 400 of the 400 references it cites were found in a registry or an index.

Management of Paediatric Ulcerative Colitis, Part 1: Ambulatory Care—An Evidence‐based Guideline From European Crohn's and Colitis Organization and European Society of Paediatric Gastroenterology, Hepatology and Nutrition

Open access
Turner, Dan, Ruemmele, Frank M., Orlanski‐Meyer, Esther, Griffiths, Anne M., de Carpi, Javier Martin, Bronsky, Jiri, Veres, Gabor, Aloi, Marina, Strisciuglio, Caterina, Braegger, Christian P., Assa, Amit, Romano, Claudio, Hussey, Séamus, Stanton, Michael, Pakarinen, Mikko, de Ridder, Lissy, Katsanos, Konstantinos, Croft, Nick, Navas‐López, Victor, Wilson, David C., Lawrence, Sally, Russell, Richard K.·2018·Journal of Pediatric Gastroenterology and Nutrition

Abstract

Background: The contemporary management of ambulatory ulcerative colitis (UC) continues to be challenging with ~20% of children needing a colectomy within childhood years. We thus aimed to standardize daily treatment of pediatric UC and inflammatory bowel diseases (IBD)‐unclassified through detailed recommendations and practice points. Methods: These guidelines are a joint effort of the European Crohn's and Colitis Organization (ECCO) and the Paediatric IBD Porto group of European Society of Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN). An extensive literature search with subsequent evidence appraisal using robust methodology was performed before 2 face‐to‐face meetings. All 40 included recommendations and 86 practice points were endorsed by 43 experts in Paediatric IBD with at least an 88% consensus rate. Results: These guidelines discuss how to optimize the use of mesalamine (including topical), systemic and locally active steroids, thiopurines and, for more severe disease, biologics. The use of other emerging therapies and the role of surgery are also covered. Algorithms are provided to aid therapeutic decision‐making based on clinical assessment and the Paediatric UC Activity Index (PUCAI). Advice on contemporary therapeutic targets incorporating the use of calprotectin and the role of therapeutic drug monitoring are presented, as well as other management considerations around pouchitis, extraintestinal manifestations, nutrition, growth, psychology, and transition. A brief section on disease classification using the PIBD‐classes criteria and IBD‐unclassified is also part of these guidelines. Conclusions: These guidelines provide a guide to clinicians managing children with UC and IBD‐unclassified management to provide modern management strategies while maintaining vigilance around appropriate outcomes and safety issues.

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Crossref · 10.1097/mpg.0000000000002035

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Metadata

Authors
Turner, D., Ruemmele, F. M., Orlanski‐Meyer, E., Griffiths, A. M., de Carpi, J. M., Bronsky, J., Veres, G., Aloi, M., Strisciuglio, C., Braegger, C. P., Assa, A., Romano, C., Hussey, S., Stanton, M., Pakarinen, M., de Ridder, L., Katsanos, K., Croft, N., Navas‐López, V., Wilson, D. C., Lawrence, S., & Russell, R. K.
Venue
Journal of Pediatric Gastroenterology and Nutrition
Publisher
Wiley
Published
2018-08
Volume
67
Issue
2
Pages
257-291
ISSN
  • 0277-2116 (ISSN-L)
  • 1536-4801
OpenAlex
W2807688850
Cited by
481
References
400
FWCI
19.71
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Management of Paediatric Ulcerative Colitis, Part 1: Ambulatory Care—An Evidence‐based Guideline From European Crohn's and Colitis Organization and European Society of Paediatric Gastroenterology, Hepatology and Nutrition. https://app.cochat.ai/papers/10.1097/mpg.0000000000002035
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Turner, D., Ruemmele, F. M., Orlanski‐Meyer, E., Griffiths, A. M., de Carpi, J. M., Bronsky, J., Veres, G., Aloi, M., Strisciuglio, C., Braegger, C. P., Assa, A., Romano, C., Hussey, S., Stanton, M., Pakarinen, M., de Ridder, L., Katsanos, K., Croft, N., Navas‐López, V., . . . Russell, R. K. (2018). Management of Paediatric Ulcerative Colitis, Part 1: Ambulatory Care—An Evidence‐based Guideline From European Crohn's and Colitis Organization and European Society of Paediatric Gastroenterology, Hepatology and Nutrition. Journal of Pediatric Gastroenterology and Nutrition. https://doi.org/10.1097/mpg.0000000000002035

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.