Adherence to Gluten‐free Diet in a Celiac Pediatric Population Referred to the General Pediatrician After Remission
Abstract
Objectives Assessment of adherence to gluten-free diet in celiac disease (CD) is generally recommended. Few data are available about consequences of transition from the referral center to the general pediatrician (GP) once remission is achieved. Methods Adherence was assessed in patients referred to the GP for an annual basis follow-up, called back for re-evaluation. Immunoglobulin A (IgA) antitissue transglutaminase (anti-tTG) antibodies and the Biagi score (BS) were determined at last follow-up at the referral center (V1), and at re-evaluation (V2). Patients were classified as adherent (BS 3-4, IgA anti-tTG Results We evaluated 200 patients. Overall, we found good adherence rates in 94.95% of patients at V1 and 83.5% at V2. IgA anti-tTG were negative in 100% at V1 and 96.97% at V2. BS is 3 to 4 in 94.5% at V1 and 84% at V2. Adherence at V2 was significantly worse than V1 (P Conclusions The BS, serology, and a clinical interview, integrated, are reliable tools for assessing pediatric adherence to gluten-free diet. We argue that referring patients to the GP after remission of CD is important, but the process must be improved and recommendations are required.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
More recent studies have reported adherence rates in paediatric patients within the range described.
“More recent studies have reported adherence rates in paediatric patients within the range described (137,139-141)”
There is no clear association between adherence to the gluten-free diet and factors such as gender, the presence of comorbidities other than anxiety and depression, the presence of coeliac disease-related symptoms at diagnosis, the presence of extradigestive symptomatology, family history of coeliac disease, or socioeconomic status.
“There is no clear association between adherence to the GFD and factors such as gender (132,137,141), the presence of comorbidities other than anxiety and depression (132,141), the presence of CD-related symptoms at diagnosis, the presence of extradigestive symptomatology, family history of CD or socioeconomic status (132).”
Cites
Charalampopoulos, D., Panayiotou, J., Chouliaras, G., Zellos, A., Kyritsi, E., & Roma, E. (2013) · European Journal of Clinical Nutrition · doi:10.1038/ejcn.2013.54 · Cited by 52 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Luque, V., Crespo‐Escobar, P., Hård af Segerstad, E. M., Koltai, T., Norsa, L., Roman, E., Vreugdenhil, A., Fueyo‐Díaz, R., & Ribes‐Koninckx, C. (2024) · Journal of Pediatric Gastroenterology and Nutrition · doi:10.1002/jpn3.12079 · Cited by 32 · see citing works
- Authors
- Sbravati, F., Pagano, S., Retetangos, C., Spisni, E., Bolasco, G., Labriola, F., Filardi, M. C., Grondona, A. G., & Alvisi, P.
- Affiliations
- Paediatric Gastroenterology Unit Ausl Bologna Italy
- University of Bologna (IT)
- Ospedale Maggiore Carlo Alberto Pizzardi (IT)
- Corresponding author
- Sbravati, Francesca
- Pagano, Sara
- Retetangos, Cristiana
- Bolasco, Giulia
- Labriola, Flavio
- Filardi, Maria C.
- Alvisi, Patrizia
- Venue
- Journal of Pediatric Gastroenterology and Nutrition
- Publisher
- Wiley
- Published
- 2020-07
- Volume
- 71
- Issue
- 1
- Pages
- 78-82
- ISSN
- 0277-2116 (ISSN-L)
- 1536-4801
- OpenAlex
- W3009282320
- Cited by
- 19
- References
- 1
- Citations by year
- 2026: 1 · 2025: 5 · 2024: 4 · 2023: 4 · 2021: 4 · 2020: 1
- FWCI
- 1.95
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Pediatric Gastroenterology and Nutrition (publishedVersion)
- PubMed (publishedVersion)
- Archivio istituzionale della ricerca (Alma Mater Studiorum Università di Bologna) (submittedVersion)
- Topics
- Health Sciences › Medicine › Gastroenterology › Celiac Disease Research and Management
- Health Sciences › Medicine › Psychiatry and Mental health › Child Nutrition and Feeding Issues
- Health Sciences › Medicine › Surgery › Eosinophilic Esophagitis
- Keywords
- celiac disease, gluten-free diet adherence, pediatric celiac disease, remission, anti-tissue transglutaminase antibodies, age as risk factor, foreign nationality, adherence assessment tools
- MeSH terms
- Pediatricians, Adolescent, Autoantibodies, Celiac Disease, Child, Humans, Immunoglobulin A, Transglutaminases, Referral and Consultation, Diet, Gluten-Free
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
