The DOI matches its Crossref record; 24 of the 24 references it cites were found in a registry or an index.
Chronotherapeutic Drug Delivery
Abstract
Living organisms follow a circadian rhythm in which physiological processes such as hormonal secretion, metabolism, heart rate, and renal output are affected by the time of day. Chronotherapy coordinates drug delivery with the circadian rhythm to enhance effectiveness and mitigate adverse effects and is achieved by delivering a drug when the system is most susceptible. Cancer is a chronotherapeutic disorder. Cancer treatment requires high doses of intravenous medication to kill cancerous cells; however, normal cells are also killed, creating intolerable side effects. This review shows that chronotherapy can play a vital role in the quality of life and survival rate for oncology patients.
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“Chronotherapeutic strategies of specifically timing the delivery of certain drugs are now being used in the treatment of certain cancers325 and may be therapeutically beneficial across various diseases326.”
From Rhythms of life: circadian disruption and brain disorders across the lifespan (2019) · cites this paper as [325]
Citations
Cites
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Rhythms of life: circadian disruption and brain disorders across the lifespan
Logan, R. W., & McClung, C. A. (2019) · Nature Reviews Neuroscience · doi:10.1038/s41583-018-0088-y · Cited by 713
The circadian clock in cancer development and therapy
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Metadata
- Authors
- Librodo, P., Buckley, M., Luk, M., & Bisso, A.
- Affiliations
- University of Arizona (US)
- Venue
- Journal of Infusion Nursing
- Published
- 2015-11
- Volume
- 38
- Issue
- Supplement 6S
- Pages
- S18-S23
- ISSN
- 1533-1458 (ISSN-L)
- OpenAlex
- W2326231814
- Cited by
- 15
- References
- 24
- Citations by year
- 2025: 1 · 2024: 1 · 2023: 1 · 2022: 3 · 2021: 1 · 2019: 1 · 2018: 1 · 2017: 1 · 2015: 1
- FWCI
- 0.55
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Infusion Nursing (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Circadian rhythm and melatonin
- Health Sciences › Medicine › Anesthesiology and Pain Medicine › Pain Management and Opioid Use
- Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmacology › Pharmacogenetics and Drug Metabolism
- Keywords
- chronotherapy, chronotherapeutic drug delivery, circadian rhythm, cancer chemotherapy, chemotherapy side effects, timing of drug administration
- MeSH terms
- Clinical Trials as Topic, Pharmaceutical Preparations, Humans, Neoplasms, Drug Delivery Systems, Drug Chronotherapy
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