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Cited by 18Cardiovascular Issues in PregnancyAortic Disease and Treatment ApproachesTakotsubo Cardiomyopathy and Associated Phenomena

The DOI matches its Crossref record; 39 of the 39 references it cites were found in a registry or an index.

Increased Risk of Aortic Dissection Associated With Pregnancy in Women With Turner Syndrome: A Systematic Review

Hynes, Jenna S., Kuller, Jeffrey A., Goldstein, Sarah A., Ward, Cary C., Muasher, Suheil J.·2020·Obstetrical & Gynecological Survey
DOI 10.1097/ogx.0000000000000833
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Abstract

Importance Turner syndrome (TS) is one of the most common chromosomal abnormalities in women. The condition is characterized by gonadal dysgenesis and is associated with structural cardiac abnormalities. Assisted reproductive technology with oocyte donation may be successful but places women with TS at increased risk of aortic dissection and death. Objective To summarize all cases of aortic dissection associated with pregnancy in women with TS and provide guidance regarding the safety of pregnancy. Evidence acquisition Systematic review of PubMed for reports of women with TS, aortic dissection, and pregnancy. Results There are 14 total reported cases of aortic dissection associated with pregnancy in women with TS. Ten of these cases occurred during pregnancy or in the first month postpartum. The majority of affected pregnancies resulted from oocyte donation, 2 of which were multiple gestations. Two women had a documented history of hypertension, and 3 pregnancies were complicated by preeclampsia. Bicuspid aortic valve and coarctation of the aorta were the most common associated cardiac anomalies. More than half of women had some degree of aortic dilatation. Two women had no identifiable risk factors. Conclusions and relevance Women with TS who desire pregnancy must be thoroughly counseled regarding the increased risk of aortic dissection during pregnancy and postpartum. Preconception consultation with maternal-fetal medicine, reproductive endocrinology, and cardiology is nece…

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Crossref · 10.1097/ogx.0000000000000833

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Metadata

Authors
Hynes, J. S., Kuller, J. A., Goldstein, S. A., Ward, C. C., & Muasher, S. J.
Affiliations
  • Resident Physician, Division of Reproductive Endocrinology and Infertility
  • Professor, Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology
  • Fellow
  • Associate Professor, Division of Cardiology, Department of Medicine
  • Duke University (US)
Corresponding author
Hynes, Jenna S.
ORCID
Venue
Obstetrical & Gynecological Survey
Publisher
Ovid Technologies (Wolters Kluwer Health)
Published
2020-09
Volume
75
Issue
9
Pages
566-575
ISSN
  • 0029-7828 (ISSN-L)
  • 1533-9866
DOI
10.1097/ogx.0000000000000833
OpenAlex
W3089083780
Cited by
18
References
39
Citations by year
2026: 2 · 2025: 4 · 2024: 5 · 2023: 5 · 2022: 2
FWCI
0.30
Type
journal article
Language
en
Open access
closed
Locations
  • Obstetrical & Gynecological Survey (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Issues in Pregnancy
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Aortic Disease and Treatment Approaches
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Takotsubo Cardiomyopathy and Associated Phenomena
Keywords
Turner syndrome, aortic dissection, pregnancy, oocyte donation, preconception counseling, cardiac monitoring, bicuspid aortic valve, coarctation of the aorta, aortic dilatation, preeclampsia, maternal-fetal medicine, reproductive endocrinology
MeSH terms
Adult, Aortic Dissection, Female, Heart Defects, Congenital, Humans, Pregnancy, Pregnancy Complications, Cardiovascular, Risk Factors, Turner Syndrome, Reproductive Techniques, Assisted

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