Application of Conjoint Analysis to Improve Reliability of Dietician Consultation in Pediatric Celiac Disease
Open accessAbstract
Introduction: Celiac disease (CD) management involves lifelong adherence to a gluten-free diet, making the dietician a key member in CD care. However, our institution lacked a standardized process for dietary consultation in newly diagnosed CD. Methods: To understand provider CD care preferences, a 2 4-1 fractional factorial conjoint analysis was performed. Attributes studied (2 levels each) included type of initial follow-up gastroenterology (GI) provider, interval from diagnosis to follow-up, concurrence of initial dietary consultation with gastroenterology visit, and on-going follow-up GI provider. CD care was standardized in July 2014 to facilitate concurrent visits with the clinician and dietician during the same clinical session. Changes to mean time of dietary consultation and reliability of dietary consultation were monitored using an individual-control and G-control chart, respectively. Standard control chart rules were followed. Results: Conjoint analysis identified shorter time to initial follow-up visit and concurrent GI/dietician visits as more important attributes in newly diagnosed CD subjects’ care. Types of follow-up provider during first or subsequent visits were identified as less important attributes. After initiation of a standardized follow-up process, a special cause was identified in December 2015 with a decrease in the mean time to dietary consultation from 30 to 20 days. In addition, standardized follow-up resulted in a more reliable process as evident by a special cause on the G-control chart in February 2015. Conclusion: Conjoint analysis identified attributes thought to be important in CD follow-up care. After redesign of our care process, a decrease in time to dietary consultation with improved reliability was observed.
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T cells recognizing avenin-specific epitopes have seldom been found in CD patients.
“Several publications have shown that avenins are free of the known CD-related immunogenic epitopes, and that T cells recognizing avenin-specific epitopes have seldom been found in CD patients (35).”
From Gluten-free diet for pediatric patients with coeliac disease: A position paper from the ESPGHAN gastroenterology committee, special interest group in coeliac disease. (2024) · cites this paper as [35]
The Introduction discusses gluten exposure in celiac disease, and the Discussion addresses dietician consultation, but neither discusses avenins or T-cell recognition. Searches for avenin-specific epitopes, T cells, and oats found no passage addressing the claim. Our copy therefore cannot verify it. (LLM, conf=0.76)
Experimental — accuracy not yet measuredAvenins are free of the known CD-related immunogenic epitopes.
“Several publications have shown that avenins are free of the known CD-related immunogenic epitopes, and that T cells recognizing avenin-specific epitopes have seldom been found in CD patients (35).”
From Gluten-free diet for pediatric patients with coeliac disease: A position paper from the ESPGHAN gastroenterology committee, special interest group in coeliac disease. (2024) · cites this paper as [35]
The Introduction (page unavailable) discusses gluten elimination and dietary management, but not avenins or immunogenic epitopes. Searches for avenins, epitopes, and avenin-specific T cells found no passage in our copy addressing the claim. (LLM, conf=0.76)
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Cites
Factors Associated with Dietary Adherence in Celiac Disease: A Nationwide Study
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Luque, V., Crespo‐Escobar, P., Hård af Segerstad, E. M., Koltai, T., Norsa, L., Roman, E., Vreugdenhil, A., Fueyo‐Díaz, R., & Ribes‐Koninckx, C. (2024) · Journal of Pediatric Gastroenterology and Nutrition · doi:10.1002/jpn3.12079 · Cited by 32 · see citing works
- Authors
- Kulkarni, S., Liss, K., & Samson, C. M.
- Affiliations
- Washington University in St. Louis (US)
- Corresponding author
- Samson, Charles M.
- Venue
- Pediatric Quality & Safety
- Published
- 2017-07
- Volume
- 2
- Issue
- 4
- Pages
- e029
- ISSN
- 2472-0054 (ISSN-L)
- PMC
- PMC6132477
- OpenAlex
- W2949535689
- Cited by
- 1
- References
- 1
- Citations by year
- 2024: 1
- FWCI
- 0.00
- Type
- journal article
- Language
- en
- Open access
- diamond
- doi.org
- Licence
- Locations
- Pediatric Quality and Safety (publishedVersion, cc-by-nc-nd)
- Europe PMC (PubMed Central) (publishedVersion, other-oa)
- PubMed Central (publishedVersion, cc-by-nc-nd)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Gastroenterology › Celiac Disease Research and Management
- Health Sciences › Health Professions › Health Information Management › Healthcare Quality and Management
- Health Sciences › Health Professions › Health Information Management › Dietetics, Nutrition, and Education
- Keywords
- pediatric celiac disease, gluten-free diet, care process redesign, process reliability, special cause variation
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