Current Perspective on Mental Stress–Induced Myocardial Ischemia
Open accessAbstract
Mental stress and emotional arousal can act as triggers of myocardial infarction and other adverse cardiovascular outcomes. This editorial presents an overview of the research on mental stress-induced myocardial ischemia (MSIMI) and comments on two investigations examining MSIMI published in this journal. These studies confirm that MSIMI is frequently observed in patients with coronary artery disease and that characteristics, such as being a woman younger than 50 years and depression, may increase the relative risk of MSIMI. The method used for determining MSIMI (i.e., assessing cardiac function as determined by echocardiography versus measurement of myocardial perfusion using single-photon emission computed tomography), as well as the nature of the mental stress protocols (i.e., one stress task versus several repeated tasks), may have important effects on the findings of MSIMI research and on their interpretation. An overview of clinical characteristics of MSIMI is presented, and the article concludes with possible directions for future MSIMI research.
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Acute mental stress combined with psychological distress has been linked to inducible myocardial ischemia among patients with coronary artery disease.
“Acute instances of mental stress combined with psychological distress (eg, depression) has also been linked to inducible myocardial ischemia among patients with coronary artery disease. 109-111”
From Psychological Health, Well-Being, and the Mind-Heart-Body Connection: A Scientific Statement From the American Heart Association (2021) · cites this paper as [110]
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Self-citation
- Authors
- Krantz, D. S., & Burg, M. M.
- Affiliations
- Uniformed Services University of the Health Sciences (US)
- Venue
- Psychosomatic Medicine
- Published
- 2014-04
- Volume
- 76
- Issue
- 3
- Pages
- 168-170
- ISSN
- 0033-3174 (ISSN-L)
- PMC
- PMC8607301
- OpenAlex
- W2321235586
- Cited by
- 43
- References
- 14
- Citations by year
- 2025: 2 · 2024: 3 · 2023: 2 · 2022: 4 · 2021: 10 · 2020: 3 · 2019: 2 · 2018: 2 · 2017: 3 · 2016: 5 · 2015: 4 · 2014: 3
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Psychosomatic Medicine (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Heart, Lung, and Blood Institute (R01HL085730)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Health and Mental Health
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Cardiac Imaging and Diagnostics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Takotsubo Cardiomyopathy and Associated Phenomena
- Keywords
- mental stress-induced myocardial ischemia, myocardial ischemia, coronary artery disease, myocardial infarction, emotional arousal, depression, women under 50, echocardiography, single photon emission computed tomography, myocardial perfusion, psychocardiology
- MeSH terms
- Coronary Disease, Depression, Female, Humans, Male, Myocardial Infarction, Stress, Psychological, Myocardial Ischemia, Survivors
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