Implications of weight gain with newer anti-retrovirals: 10-year predictions of cardiovascular disease and diabetes

McCann, Kaitlyn; Shah, Shahini; Hindley, Laura; Hill, Andrew; Qavi, Ambar; Simmons, Bryony; Serenata, Celicia; Sokhela, Simiso; Venter, Willem D.F.

doi:10.1097/qad.0000000000002930

Implications of weight gain with newer anti-retrovirals: 10-year predictions of cardiovascular disease and diabetes

Objective: To evaluate the long-term risks of type 2 diabetes mellitus (T2DM) and cardiovascular disease (CVD) secondary to weight gain and clinical obesity associated with the initiation of integrase strand transfer inhibitors and tenofovir alafenamide (TAF) in the ADVANCE trial using validated …