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Screening, prevention, and treatment for hyperinfection syndrome and disseminated infections caused by Strongyloides stercoralis
Open accessAbstract
PURPOSE OF REVIEW: This review discusses the latest approaches to the diagnosis and treatment of patients with strongyloidiasis, with an emphasis on infection in the immunocompromised host and the risk for disseminated strongyloidiasis. RECENT FINDINGS: The differences in acute, chronic, accelerated autoinfection, and disseminated disease in Strongyloides stercoralis infection are explored with particular emphasis on early diagnosis, treatment, and prevention. The goals of treatment are investigated for the different infection states. Predisposing risks for dissemination are delineated, and the roles played for newer diagnostics in the identification of at-risk individuals are detailed. SUMMARY: The use of newer diagnostic tests and broader screening of immunocompromised patients from Strongyloides-endemic areas is of paramount importance, particularly if prevention of life-threatening dissemination is the goal.
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Citations
Cited by
Ivermectin versus albendazole or thiabendazole for Strongyloides stercoralis infection
Henriquez-Camacho, C., Gotuzzo, E., Echevarria, J., White Jr, A. C., Terashima, A., Samalvides, F., Pérez-Molina, J. A., & Plana, M. N. (2016) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd007745.pub3 · Cited by 193
Diplomatic assistance: can helminth-modulated macrophages act as treatment for inflammatory disease?
Steinfelder, S., O’Regan, N. L., & Hartmann, S. (2016) · PLOS Pathogens · doi:10.1371/journal.ppat.1005480 · Cited by 36
Ye, L., Taylor, G. P., & Rosadas, C. (2022) · Frontiers in Medicine · doi:10.3389/fmed.2022.832430 · Cited by 36
Metadata
- Authors
- Mejia, R., & Nutman, T. B.
- Venue
- Current Opinion in Infectious Diseases
- Published
- 2012-08
- Volume
- 25
- Issue
- 4
- Pages
- 458-463
- ISSN
- 0951-7375 (ISSN-L)
- OpenAlex
- W2077806387
- Cited by
- 392
- References
- 0
- FWCI
- 16.87
- Type
- journal article
- Language
- en
- Open access
- green
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- CoChat. (2026). Citation check: Screening, prevention, and treatment for hyperinfection syndrome and disseminated infections caused by Strongyloides stercoralis. https://app.cochat.ai/papers/10.1097/qco.0b013e3283551dbd
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- Mejia, R., & Nutman, T. B. (2012). Screening, prevention, and treatment for hyperinfection syndrome and disseminated infections caused by Strongyloides stercoralis. Current Opinion in Infectious Diseases. https://doi.org/10.1097/qco.0b013e3283551dbd
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Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
