Student or educator? Sign up with your school email and get 6 months of Pro free.
CoChat
Sign Up
Cited by 9

The DOI matches its Crossref record; 16 of the 16 references it cites were found in a registry or an index.

Risk Factors for Anterior Hypopituitarism in Patients With Traumatic Brain Injury

You, Wendong, Zhu, Yuanrun, Wen, Liang, Sun, Yun, Pan, Desheng, Yang, Xiaofeng·2019·Journal of Craniofacial Surgery
DOI 10.1097/scs.0000000000005405
Open this paper in CoChat — free account

Abstract

Background: Hypopituitarism is a common but potentially undiagnosed complication in patients who suffer traumatic brain injury (TBI). The identification of risk factors of hypopituitarism after TBI is vital to establish a rational testing approach for these patients. Methods: The authors retrospectively reviewed the case records of patients with TBI, who underwent pituitary function evaluation in our department between January 2014 and December 2016. Results: In all, 193 patients (66.3% male) hospitalized with TBI were included in this study. Anterior hypopituitarism was observed in 33 (17.1%) patients, with 4.7% of the patients having multiple pituitary axes dysfunction. Patients with hypopituitarism had a longer length of ICU stay (8.7 ± 5.5 versus 3.3 ± 4.6,P < 0.001), longer length of total hospital stay (28.7 ± 20.1 versus 21.0 ± 15.8,P = 0.011), and lower Glasgow coma scale (GCS) on admission (9.1 ± 3.5 versus 11.8 ± 3.6,P < 0.001) than those without the condition. Length of ICU stay (P = 0.004, OR = 1.253) and intracranial hypertension (P = 0.027, OR = 3.206) were independent risk factors for posttraumatic hypopituitarism. Conclusions: The prevalence of anterior hypopituitarism was estimated to be 17.1%. Patients with intracranial hypertension and longer length of ICU stay are at risk of hypopituitarism. Routine pituitary function evaluation is indicated for this group of patients.

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1097/scs.0000000000005405

Cites

16 of 16 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Research works printed but not linked: 16

  1. Taylor, 2017, Traumatic brain injury-related emergency department visits, hospitalizations, and deaths - United States, 2007 and 2013, MMWR Surveill Summ (Washington, DC: 2002), 66, 1, 10.15585/mmwr.ss6609a1 · DOI · Paper page
  2. Cheng, 2017, Trends in traumatic brain injury mortality in China, 2006–2013: A population-based longitudinal study, 14, e1002332
  3. Salmond, 2005, Cognitive outcome in traumatic brain injury survivors, Curr Opin Crit Care, 11, 111, 10.1097/01.ccx.0000155358.31983.37 · DOI
  4. Fernandez-Rodriguez, 2011, Hypopituitarism following traumatic brain injury: determining factors for diagnosis, Front Endocrinol (Lausanne), 2, 25, 10.3389/fendo.2011.00025 · DOI · Paper page
  5. Aimaretti, 2005, Residual pituitary function after brain injury-induced hypopituitarism: a prospective 12-month study, J Clin Endocrinol Metab, 90, 6085, 10.1210/jc.2005-0504 · DOI · Paper page
  6. Leal-Cerro, 2005, Prevalence of hypopituitarism and growth hormone deficiency in adults long-term after severe traumatic brain injury, Clin Endocrinol (Oxf), 62, 525, 10.1111/j.1365-2265.2005.02250.x · DOI · Paper page
  7. Nemes, 2015, Predictors of post-traumatic pituitary failure during long-term follow-up, Hormones (Athens, Greece), 14, 383
  8. Tanriverdi, 2015, Neuroendocrine disturbances after brain damage: an important and often undiagnosed disorder, J Clin Med, 4, 847, 10.3390/jcm4050847 · DOI
  9. Hellawell, 2001, Relatives’ reports of long term problems following traumatic brain injury or subarachnoid haemorrhage, Disab Rehabil, 23, 300, 10.1080/769979114 · DOI
  10. Silva, 2015, Predictors of hypopituitarism in patients with traumatic brain injury, J Neurotrauma, 32, 1789, 10.1089/neu.2015.3998 · DOI
  11. Wagner, 2010, Acute gonadotroph and somatotroph hormonal suppression after traumatic brain injury, J Neurotrauma, 27, 1007, 10.1089/neu.2009.1092 · DOI · Paper page
  12. Karamouzis, 2016, Clinical and diagnostic approach to patients with hypopituitarism due to traumatic brain injury (TBI), subarachnoid hemorrhage (SAH), and ischemic stroke (IS), Endocrine, 52, 441, 10.1007/s12020-015-0796-2 · DOI
  13. Agha, 2005, The natural history of post-traumatic hypopituitarism: implications for assessment and treatment, Am J Med, 118, 1416, 10.1016/j.amjmed.2005.02.042 · DOI · Paper page
  14. Agha, 2004, Anterior pituitary dysfunction in survivors of traumatic brain injury, J Clin Endocrinol Metab, 89, 4929, 10.1210/jc.2004-0511 · DOI · Paper page
  15. Bondanelli, 2004, Occurrence of pituitary dysfunction following traumatic brain injury, J Neurotrauma, 21, 685, 10.1089/0897715041269713 · DOI · Paper page
  16. Agha, 2005, The natural history of post-traumatic neurohypophysial dysfunction, Eur J Endocrinol, 152, 371, 10.1530/eje.1.01861 · DOI · Paper page

Cited by

See all 9

Metadata

Authors
You, W., Zhu, Y., Wen, L., Sun, Y., Pan, D., & Yang, X.
Affiliations
  • Department of Neurosurgery
  • Department of Rehabilitation Medicine, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Venue
Journal of Craniofacial Surgery
Publisher
Ovid Technologies (Wolters Kluwer Health)
Published
2019-10
Volume
30
Issue
7
Pages
2119-2123
ISSN
  • 1049-2275
  • 1536-3732
DOI
10.1097/scs.0000000000005405
Cited by
9
References
16
Language
en

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.