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Cited by 858Enhanced Recovery After SurgeryCardiac, Anesthesia and Surgical OutcomesHemodynamic Monitoring and Therapy

The DOI matches its Crossref record; 27 of the 27 references it cites were found in a registry or an index.

Personalised Prehabilitation in High-risk Patients Undergoing Elective Major Abdominal Surgery: A Randomized Blinded Controlled Trial

Open access
Barberan-Garcia, Anael, Ubré, Marta, Roca, Josep, Lacy, Antonio M., Burgos, Felip, Risco, Raquel, Momblán, Dulce, Balust, Jaume, Blanco, Isabel, Martínez-Pallí, Graciela·2018·Annals of Surgery
DOI 10.1097/sla.0000000000002293
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Abstract

OBJECTIVE: The aim of this study was to assess the impact of personalized prehabilitation on postoperative complications in high-risk patients undergoing elective major abdominal surgery. SUMMARY BACKGROUND DATA: Prehabilitation, including endurance exercise training and promotion of physical activity, in patients undergoing major abdominal surgery has been postulated as an effective preventive intervention to reduce postoperative complications. However, the existing studies provide controversial results and show a clear bias toward low-risk patients. METHODS: This was a randomized blinded controlled trial. Eligible candidates accepting to participate were blindly randomized (1:1 ratio) to control (standard care) or intervention (standard care + prehabilitation) groups. Inclusion criteria were: i) age >70 years; and/or, ii) American Society of Anesthesiologists score III/IV. Prehabilitation covered 3 actions: i) motivational interview; ii) high-intensity endurance training; and promotion of physical activity. The main study outcome was the proportion of patients suffering postoperative complications. Secondary outcomes included the endurance time (ET) during cycle-ergometer exercise. RESULTS: We randomized 71 patients to the control arm and 73 to intervention. After excluding 19 patients because of changes in the surgical plan, 63 controls and 62 intervention patients were included in the intention-to-treat analysis. The intervention group enhanced aerobic capacity [ΔET 135 (218) %; P < 0.001), reduced the number of patients with postoperative complications by 51% (relative risk 0.5; 95% confidence interval, 0.3-0.8; P = 0.001) and the rate of complications [1.4 (1.6) and 0.5 (1.0) (P = 0.001)] as compared with controls. CONCLUSION: Prehabilitation enhanced postoperative clinical outcomes in high-risk candidates for elective major abdominal surgery, which can be explained by the increased aerobic capacity.

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Crossref · 10.1097/sla.0000000000002293

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Research works printed but not linked: 1

  1. Hulzebos, 2012, Preoperative physical therapy for elective cardiac patients, Cochrane Database Syst Rev, 11, CD010118

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Metadata

Authors
Barberan-Garcia, A., Ubré, M., Roca, J., Lacy, A. M., Burgos, F., Risco, R., Momblán, D., Balust, J., Blanco, I., & Martínez-Pallí, G.
Affiliations
  • Hospital Clínic de Barcelona (ES)
  • Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (ES)
Corresponding author
  • Roca, Josep
  • Burgos, Felip
  • Blanco, Isabel
ORCID
Venue
Annals of Surgery
Publisher
Ovid Technologies (Wolters Kluwer Health)
Published
2018-01
Volume
267
Issue
1
Pages
50-56
ISSN
0003-4932 (ISSN-L)
DOI
10.1097/sla.0000000000002293
OpenAlex
W2612931787
Cited by
858
References
27
Citations by year
2026: 100 · 2025: 95 · 2024: 95 · 2023: 101 · 2022: 122 · 2021: 120 · 2020: 94 · 2019: 80 · 2018: 48
FWCI
62.77
Type
journal article
Language
en
Open access
Licence
other-oa
Locations
  • Annals of Surgery (publishedVersion)
  • PubMed (publishedVersion)
  • Zenodo (CERN European Organization for Nuclear Research) (submittedVersion, other-oa)
Topics
  • Health Sciences › Medicine › Surgery › Enhanced Recovery After Surgery
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac, Anesthesia and Surgical Outcomes
  • Health Sciences › Medicine › Surgery › Hemodynamic Monitoring and Therapy
Keywords
prehabilitation, high-risk surgical patients, postoperative complications, endurance training, cardiorespiratory fitness, motivational interviewing, physical activity promotion, older adults
MeSH terms
Abdomen, Aged, Exercise Therapy, Female, Humans, Male, Postoperative Complications, Preoperative Care, Retrospective Studies, Risk Factors, Digestive System Surgical Procedures, Treatment Outcome, Elective Surgical Procedures, Precision Medicine

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