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Phase I/II Clinical Evaluation of StrataGraft: A Consistent, Pathogen-Free Human Skin Substitute
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“Immortalized cell lines can be used in most research instead of primary cells because they offer several advantages, including cost-effectiveness, ease of use, unlimited availability of materials, and the bypassing of ethical concerns associated with animal and human tissue use [14,15,16].”
From Cell Immortality: In Vitro Effective Techniques to Achieve and Investigate Its Applications and Challenges (2024) · cites this paper as [16]
In the citing paper
“Generally, various cell lines have revolutionized scientific investigations and have found applications in vaccine development, drug testing for metabolism and toxicity, generating antibodies, exploring gene functions, creating artificial tissues like synthetic skin, and producing biologic substances such as therapeutic proteins [16,19,26].”
From Cell Immortality: In Vitro Effective Techniques to Achieve and Investigate Its Applications and Challenges (2024) · cites this paper as [16]
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Research works printed but not linked: 28
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- Supp, 2004, Expression of human beta-defensins HBD-1, HBD-2, and HBD-3 in cultured keratinocytes and skin substitutes., Burns, 30, 643, 10.1016/j.burns.2004.03.012 · DOI
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- Allen-Hoffmann, 2000, Normal growth and differentiation in a spontaneously immortalized near-diploid human keratinocyte cell line, NIKS., J Invest Dermatol, 114, 444, 10.1046/j.1523-1747.2000.00869.x · DOI
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- Hefton, 1983, Grafting of burn patients with allografts of cultured epidermal cells., Lancet, 2, 428, 10.1016/S0140-6736(83)90392-6 · DOI
- Madden, 1986, Grafting of cultured allogeneic epidermis on second- and third-degree burn wounds on 26 patients., J Trauma, 26, 955, 10.1097/00005373-198611000-00001 · DOI
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Cited by
Chalak, M., Hesaraki, M., Mirbahari, S. N., Yeganeh, M., Abdi, S., Rajabi, S., & Hemmatzadeh, F. (2024) · Life · doi:10.3390/life14030417 · Cited by 66
Metadata
- Authors
- Schurr, M. J., Foster, K. N., Centanni, J. M., Comer, A. R., Wicks, A., Gibson, A. L., Thomas-Virnig, C. L., Schlosser, S. J., Faucher, L. D., Lokuta, M. A., & Allen-Hoffmann, B. L.
- Venue
- Journal of Trauma: Injury, Infection & Critical Care
- Published
- 2009-03
- Volume
- 66
- Issue
- 3
- Pages
- 866-874
- ISSN
- 0022-5282
- PMC
- PMC2679581
- Cited by
- 49
- References
- 0
- Language
- en
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- CoChat. (2026). Citation check: Phase I/II Clinical Evaluation of StrataGraft: A Consistent, Pathogen-Free Human Skin Substitute. https://app.cochat.ai/papers/10.1097/ta.0b013e31819849d6
- The paper
- Schurr, M. J., Foster, K. N., Centanni, J. M., Comer, A. R., Wicks, A., Gibson, A. L., Thomas-Virnig, C. L., Schlosser, S. J., Faucher, L. D., Lokuta, M. A., & Allen-Hoffmann, B. L. (2009). Phase I/II Clinical Evaluation of StrataGraft: A Consistent, Pathogen-Free Human Skin Substitute. Journal of Trauma: Injury, Infection & Critical Care. https://doi.org/10.1097/ta.0b013e31819849d6