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Cited by 41Transplantation: Methods and OutcomesRespiratory Support and MechanismsNeonatal Respiratory Health Research

The DOI matches its Crossref record; 35 of the 35 references it cites were found in a registry or an index.

Lung Transplantation as a Therapeutic Option in Acute Respiratory Distress Syndrome

Open access
Chang, Youjin, Lee, Sang Oh, Shim, Tae Sun, Choi, Sae Hoon, Kim, Hyung Ryul, Kim, Yong-Hee, Kim, Dong Kwan, Do, Kyung-Hyun, Choi, In-Cheol, Hong, Sang-Bum, Park, Seung-Il·2018·Transplantation
DOI 10.1097/tp.0000000000002004
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Abstract

BACKGROUND: Lung transplantation (LTPL) is considered as a salvage therapeutic option in patients with end-stage lung disease. However, there is a lack of sufficient data on the use of LTPL in patients with acute respiratory distress syndrome (ARDS). Although there are few case reports on lung transplant for ARDS, no case series exists up to date. The aim of this study was to evaluate the clinical outcomes of patients with ARDS in accordance with the LTPL status. METHODS: Patients who had severe ARDS (PaO2/FiO2 ratio ≤ 100 mm Hg with positive end-expiratory pressure ≥ 5 cm H2O) and were listed for LTPL with no underlying end-stage lung disease were included in this single-center retrospective study. Demographic and clinical data of the patients were collected and analyzed. RESULTS: Fourteen patients were listed for LTPL due to severe ARDS. All patients received mechanical ventilation, and 12 (86%) patients underwent extracorporeal membrane oxygenation. Of the 9 patients who underwent LTPL, 8 (89%) survived, whereas only 1 (20%) patient out of those who did not receive LTPL survived. The median survival time of the patients who underwent LTPL was 1996 days (interquartile range [IQR], 872-2239), compared with 49 days (IQR, 872-2239) in patients who did not undergo LTPL. The median survival time after LTPL was 64 months (IQR, 28-72). The 3-year survival rate of the recipients was 78%. CONCLUSIONS: LTPL may be considered as a therapeutic option in a select group of patients with severe ARDS. However, the irreversibility of the patient's lung status should be considered.

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Crossref · 10.1097/tp.0000000000002004

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  1. 1985, A case report. The Toronto Lung Transplant group., J Thorac Cardiovasc Surg, 89, 734

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Metadata

Authors
Chang, Y., Lee, S. O., Shim, T. S., Choi, S. H., Kim, H. R., Kim, Y.-H., Kim, D. K., Do, K.-H., Choi, I.-C., Hong, S.-B., & Park, S.-I.
Affiliations
  • Inje University (KR)
  • Asan Medical Center (KR)
Corresponding author
  • Hong, Sang-Bum
  • Park, Seung-Il
ORCID
Venue
Transplantation
Publisher
Ovid Technologies (Wolters Kluwer Health)
Published
2018-05
Volume
102
Issue
5
Pages
829-837
ISSN
0041-1337 (ISSN-L)
DOI
10.1097/tp.0000000000002004
OpenAlex
W2769638454
Semantic Scholar
b909d825b04ece50b3b5849c4cc95bdaf00be862
Cited by
41
References
35
Citations by year
2026: 2 · 2024: 4 · 2023: 4 · 2022: 12 · 2021: 10 · 2020: 8 · 2018: 1
FWCI
2.52
Type
journal article
Language
en
Open access
Locations
  • Transplantation (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Surgery › Transplantation: Methods and Outcomes
  • Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Respiratory Support and Mechanisms
  • Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Neonatal Respiratory Health Research
Keywords
lung transplantation, acute respiratory distress syndrome, extracorporeal membrane oxygenation, mechanical ventilation, survival outcomes, end-stage lung disease, PaO2/FiO2 ratio
MeSH terms
Clinical Decision-Making, Adult, Aged, Female, Health Status, Humans, Male, Middle Aged, Respiration, Artificial, Respiratory Distress Syndrome, Retrospective Studies, Risk Factors, Severity of Illness Index, Time Factors, Waiting Lists, Extracorporeal Membrane Oxygenation, Lung Transplantation, Treatment Outcome, Patient Selection, Seoul

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CoChat. (2026). Citation check: Lung Transplantation as a Therapeutic Option in Acute Respiratory Distress Syndrome. https://app.cochat.ai/papers/10.1097/tp.0000000000002004
The paper
Chang, Y., Lee, S. O., Shim, T. S., Choi, S. H., Kim, H. R., Kim, Y.-H., Kim, D. K., Do, K.-H., Choi, I.-C., Hong, S.-B., & Park, S.-I. (2018). Lung Transplantation as a Therapeutic Option in Acute Respiratory Distress Syndrome. Transplantation. https://doi.org/10.1097/tp.0000000000002004