The DOI matches its Crossref record; 65 of the 65 references it cites were found in a registry or an index.
Polysubstance use: diagnostic challenges, patterns of use and health
Abstract
PURPOSE OF REVIEW: Polysubstance use is common, particularly amongst some age groups and subcultures. It is also associated with elevated risk of psychiatric and physical health problems. We review the recent research findings, comment on changes to polysubstance diagnoses, report on contemporary clinical and epidemiological polysubstance trends, and examine the efficacy of preventive and treatment approaches. RECENT FINDINGS: Approaches to describing polysubstance use profiles are becoming more sophisticated. Models over the last 18 months that employ latent class analysis typically report a no use or limited-range cluster (alcohol, tobacco and marijuana), a moderate-range cluster (limited range and amphetamine derivatives), and an extended-range cluster (moderate range, and nonmedical use of prescription drugs and other illicit drugs). Prevalence rates vary as a function of the population surveyed. Wide-ranging polysubstance users carry higher risk of comorbid psychopathology, health problems, and deficits in cognitive functioning. SUMMARY: Wide-ranging polysubstance use is more prevalent in subcultures such as 'ravers' (dance club attendees) and those already dependent on substances. Health risks are elevated in these groups. Research into the prevention and treatment of polysubstance use is underdeveloped. There may be benefit in targeting specific polysubstance use and risk profiles in prevention and clinical research.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Diagnostic and Statistical Manual of Mental Disorders
Williams, J. B. W., & First, M. (2013) · Encyclopedia of Social Work · doi:10.1093/acrefore/9780199975839.013.104 · Cited by 109,519
DSM-5 criteria for substance use disorders: recommendations and rationale
Hasin, D. S., O’Brien, C. P., Auriacombe, M., Borges, G., Bucholz, K., Budney, A., Compton, W. M., Crowley, T., Ling, W., Petry, N. M., et al. (2013) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2013.12060782 · Cited by 1,622
Polydrug abuse: a review of opioid and benzodiazepine combination use
Jones, J. D., Mogali, S., & Comer, S. D. (2012) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2012.07.004 · Cited by 703
Widespread and sustained cognitive deficits in alcoholism: a meta-analysis.
Stavro, K., Pelletier, J., & Potvin, S. (2013) · Addiction Biology · doi:10.1111/j.1369-1600.2011.00418.x · Cited by 594
Moss, H. B., Chen, C. M., & Yi, H.-Y. (2014) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2013.12.011 · Cited by 488
Brennan, J., Kuhns, L. M., Johnson, A. K., Belzer, M., Wilson, E. C., Garofalo, R., & the Adolescent Medicine Trials Network for HIV/AIDS Interventions (2012) · American Journal of Public Health · doi:10.2105/ajph.2011.300433 · Cited by 429
Concurrent and simultaneous drug and alcohol use: Results of the 2000 National Alcohol Survey
Midanik, L. T., Tam, T. W., & Weisner, C. (2007) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2007.02.024 · Cited by 344
Calcaterra, S., Glanz, J., & Binswanger, I. A. (2013) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2012.11.018 · Cited by 330
Excess Significance Bias in the Literature on Brain Volume Abnormalities
Ioannidis, J. P. A. (2011) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2011.28 · Cited by 299
Conrod, P. J., O’Leary-Barrett, M., Newton, N., Topper, L., Castellanos-Ryan, N., Mackie, C., & Girard, A. (2013) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2013.651 · Cited by 288
Research works printed but not linked: 5
- Fernandez-Calderon, 2011, Polysubstance use patterns in underground rave attenders: a cluster analysis., J Drug Educ, 41, 183, 10.2190/DE.41.2.d · doi:10.2190/de.41.2.d
- Miller, 2013, Energy drinks and alcohol: research supported by industry may be downplaying harms., BMJ, 347, f5345, 10.1136/bmj.f5345 · doi:10.1136/bmj.f5345
- Garcia de Oliveira, 2013, Polydrug use among college students in Brazil: a nationwide survey., Rev Bras Psiquiatr, 35, 221, 10.1590/1516-4446-2012-0775 · doi:10.1590/1516-4446-2012-0775
- Measham, 2013, Exploring patterns of weekend polydrug use within local leisure scenes across the English night time economy., Criminol Crim Justice, 9, 437, 10.1177/1748895809343406 · doi:10.1177/1748895809343406
- Kelly, 2014, Is there any evidence of changes in patterns of concurrent drug use among young Australians 18-29 years between 2007 and 2010 Addict, Behav, 39, 1249
Cited by
Connor, J. P., Haber, P. S., & Hall, W. D. (2016) · The Lancet · doi:10.1016/s0140-6736(15)00122-1 · Cited by 389
Self-citationPolysubstance Use: A Broader Understanding of Substance Use During the Opioid Crisis
Cicero, T. J., Ellis, M. S., & Kasper, Z. A. (2020) · American Journal of Public Health · doi:10.2105/ajph.2019.305412 · Cited by 285
Emotion Regulation and Substance Use: A Meta-Analysis
Weiss, N. H., Kiefer, R., Goncharenko, S., Raudales, A. M., Forkus, S. R., Schick, M. R., & Contractor, A. A. (2022) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2021.109131 · Cited by 235
Treatment of stimulant use disorder: A systematic review of reviews
Ronsley, C., Nolan, S., Knight, R., Hayashi, K., Klimas, J., Walley, A., Wood, E., & Fairbairn, N. (2020) · PLOS ONE · doi:10.1371/journal.pone.0234809 · Cited by 222
Multiple DSM‐5 substance use disorders: A national study of US adults
McCabe, S. E., West, B. T., Jutkiewicz, E. M., & Boyd, C. J. (2017) · Human Psychopharmacology: Clinical and Experimental · doi:10.1002/hup.2625 · Cited by 133
Metadata
- Authors
- Connor, J. P., Gullo, M. J., White, A., & Kelly, A. B.
- Venue
- Current Opinion in Psychiatry
- Published
- 2014-07
- Volume
- 27
- Issue
- 4
- Pages
- 269-275
- ISSN
- 0951-7367 (ISSN-L)
- OpenAlex
- W2047211068
- Cited by
- 461
- References
- 65
- FWCI
- 14.83
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Polysubstance use: diagnostic challenges, patterns of use and health. https://app.cochat.ai/papers/10.1097/yco.0000000000000069
- The paper
- Connor, J. P., Gullo, M. J., White, A., & Kelly, A. B. (2014). Polysubstance use: diagnostic challenges, patterns of use and health. Current Opinion in Psychiatry. https://doi.org/10.1097/yco.0000000000000069
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.