The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
A simple DNA gate motif for synthesizing large-scale circuits
Open accessAbstract
The prospects of programming molecular systems to perform complex autonomous tasks have motivated research into the design of synthetic biochemical circuits. Of particular interest to us are cell-free nucleic acid systems that exploit non-covalent hybridization and strand displacement reactions to create cascades that implement digital and analogue circuits. To date, circuits involving at most tens of gates have been demonstrated experimentally. Here, we propose a simple DNA gate architecture that appears suitable for practical synthesis of large-scale circuits involving possibly thousands of gates.
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Cites
The chemical basis of morphogenesis
Turing, A. M. (1952) · Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences · doi:10.1098/rstb.1952.0012 · Cited by 11,733
Design and self-assembly of two-dimensional DNA crystals
Winfree, E., Liu, F., Wenzler, L. A., & Seeman, N. C. (1998) · Nature · doi:10.1038/28998 · Cited by 2,857
Self-citationCOPASI—a COmplex PAthway SImulator
Hoops, S., Sahle, S., Gauges, R., Lee, C., Pahle, J., Simus, N., Singhal, M., Xu, L., Mendes, P., & Kummer, U. (2006) · Bioinformatics · doi:10.1093/bioinformatics/btl485 · Cited by 2,618
Cited by
Principles and Applications of Nucleic Acid Strand Displacement Reactions
Simmel, F. C., Yurke, B., & Singh, H. R. (2019) · Chemical Reviews · doi:10.1021/acs.chemrev.8b00580 · Cited by 792
Materials learning from life: concepts for active, adaptive and autonomous molecular systems
Merindol, R., & Walther, A. (2017) · Chemical Society Reviews · doi:10.1039/c6cs00738d · Cited by 533
Nucleic Acid Databases and Molecular-Scale Computing
Song, X., & Reif, J. (2019) · ACS Nano · doi:10.1021/acsnano.9b02562 · Cited by 73
Metadata
- Authors
- Qian, L., & Winfree, E.
- Venue
- Journal of The Royal Society Interface
- Publisher
- The Royal Society
- Published
- 2011-02-04
- Volume
- 8
- Issue
- 62
- Pages
- 1281-1297
- ISSN
- 1742-5662 (ISSN-L)
- 1742-5689
- OpenAlex
- W2104146049
- Cited by
- 251
- References
- 3
- FWCI
- 6.94
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Qian, L., & Winfree, E. (2011). A simple DNA gate motif for synthesizing large-scale circuits. Journal of The Royal Society Interface. https://doi.org/10.1098/rsif.2010.0729
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
