CoChat
Sign Up
Cited by 58Chromosomal and Genetic VariationsGenetic and Clinical Aspects of Sex Determination and Chromosomal AbnormalitiesMicrotubule and mitosis dynamics

Unravelling the mystery of female meiotic drive: where we are

Open access
Clark, Frances E., Akera, Takashi·2021·Open Biology
DOI 10.1098/rsob.210074PMC PMC8437031
Open this paper in CoChat — free account

Abstract

Female meiotic drive is the phenomenon where a selfish genetic element alters chromosome segregation during female meiosis to segregate to the egg and transmit to the next generation more frequently than Mendelian expectation. While several examples of female meiotic drive have been known for many decades, a molecular understanding of the underlying mechanisms has been elusive. Recent advances in this area in several model species prompts a comparative re-examination of these drive systems. In this review, we compare female meiotic drive of several animal and plant species, highlighting pertinent similarities.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1098/rsob.210074

Cites

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • The two examples of female meiotic drive discovered in plants so far, in maize and monkeyflower, are not associated with translocations.

    “The two examples of female meiotic drive discovered in plants so far, in maize and monkeyflower (Buckler et al., 1999; Fishman and Saunders, 2008; Clark and Akera, 2021; Finseth et al., 2021), are not associated with translocations.”

    From Genomics of plant speciation (2023) · cites this paper as Clark and Akera, 2021

    The sections on non-centromeric drivers and asymmetric kinetochores describe female meiotic drive in maize and monkeyflower, respectively. But the B-chromosome section also describes female meiotic drive in lilies and other plants, so the review does not support the claim that these are the only two plant examples. The passages do not explicitly establish whether the maize and monkeyflower cases are associated with translocations. (LLM, conf=0.86)

    Experimental — accuracy not yet measured

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

The citation lists haven’t been fetched yet

References 115 · Cited by 58

Research works printed but not linked: 113

  1. [1]Rice WR. 2013 Nothing in genetics makes sense except in light of genomic conflict. Annu. Rev. Ecol. Evol. Syst. 44, 217- 237. (10.1146/annurev-ecolsys-110411-160242) · DOI
  2. [2]Werren JH. 2011 Selfish genetic elements, genetic conflict, and evolutionary innovation. Proc. Natl Acad. Sci. USA 108, 10 863- 10 870. (10.1073/pnas.1102343108) PMC3131821 21690392 · DOI
  3. [3]Burt A, Trivers R. 2008 Genes in conflict: the biology of selfish genetic elements, pp. 325- 380. Cambridge, MA: Belknap Press.
  4. [4]Jones RN. 1991 B-chromosome drive. Am. Nat. 137, 430- 442. (10.1086/285175) · DOI
  5. [5]Camacho JP, Sharbel TF, Beukeboom LW. 2000 B-chromosome evolution. Phil. Trans. R. Soc. B 355, 163- 178. (10.1098/rstb.2000.0556) 10724453 PMC1692730 · DOI
  6. [6]Brandvain Y, Coop G. 2015 Sperm should evolve to make female meiosis fair. Evolution 69, 1004- 1014. (10.1111/evo.12621) 25662355 PMC5539998 · DOI
  7. [7]Lindholm AK et al. 2016 The ecology and evolutionary dynamics of meiotic drive. Trends Ecol. Evol. 31, 315- 326. (10.1016/j.tree.2016.02.001) 26920473 · DOI
  8. [8]Zanders SE, Unckless RL. 2019 Fertility costs of meiotic drivers. Curr. Biol. 29, R512- R520. (10.1016/j.cub.2019.03.046) 31163165 PMC6586414 · DOI
  9. [9]Sandler L, Novitski E. 1957 Meiotic drive as an evolutionary force. Am. Nat. 91, 105- 110. (10.1086/281969) · DOI
  10. [10]Hu W, Jiang ZD, Suo F, Zheng JX, He WZ, Du LL. 2017 A large gene family in fission yeast encodes spore killers that subvert Mendel's law. Elife 6, 1- 19. (10.7554/elife.26057) PMC5478263 28631610 · DOI
  11. [11]López HJF, Zanders SE. 2018 Veni, vidi, vici: the success of wtf meiotic drivers in fission yeast. Yeast 35, 447- 453. (10.1002/yea.3305) 29322557 PMC6033644 · DOI
  12. [12]Eickbush MT, Young JM, Zanders SE. 2019 Killer meiotic drive and dynamic evolution of the WTF gene family. Mol. Biol. Evol. 36, 1201- 1214. (10.1093/molbev/msz052) 30991417 PMC6526906 · DOI
  13. [13]Bravo NMA, Nuckolls NL, Zanders SE. 2018 Genetic villains: killer meiotic drivers. Trends Genet. 34, 424- 433. (10.1016/j.tig.2018.02.003) 29499907 PMC5959745 · DOI
  14. [14]Courret C, Chang CH, Wei KHC, Montchamp-Moreau C, Larracuente AM. 2019 Meiotic drive mechanisms: lessons from Drosophila. Proc. R. Soc. B 286, 20191430. (10.1098/rspb.2019.1430) PMC6834043 31640520 · DOI
  15. [15]Kruger AN, Mueller JL. 2021 Mechanisms of meiotic drive in symmetric and asymmetric meiosis. Cell Mol. Life Sci. 78, 3205- 3218. (10.1007/s00018-020-03735-0) 33449147 PMC8043981 · DOI
  16. [16]Pardo-Manuel de Villena F, Sapienza C. 2001 Female meiosis drives karyotypic evolution in mammals. Genetics 159, 1179- 1189. (10.1093/genetics/159.3.1179) 11729161 PMC1461872 · DOI
  17. [17]Brandvain Y, Coop G. 2012 Scrambling eggs: meiotic drive and the evolution of female recombination rates. Genetics 190, 709- 723. (10.1534/genetics.111.136721) 22143919 PMC3276612 · DOI
  18. [18]Pardo-Manuel De Villena F, Sapienza C. 2001 Nonrandom segregation during meiosis: the unfairness of females. Mamm. Genome 12, 331- 339. (10.1007/s003350040003) 11331939 · DOI
  19. [19]Gorelick R, Carpinone J, Derraugh LJ. 2017 No universal differences between female and male eukaryotes: anisogamy and asymmetrical female meiosis. Biol. J. Linn. Soc. 120, 1- 21. (10.1111/bij.12874) · DOI
  20. [20]Lenormand T, Engelstädter J, Johnston SE, Wijnker E, Haag CR. 2016 Evolutionary mysteries in meiosis. Phil. Trans. R. Soc. B 371, 20160001. (10.1098/rstb.2016.0001) 27619705 PMC5031626 · DOI
  21. [21]Fabritius AS, Ellefson ML, McNally FJ. 2011 Nuclear and spindle positioning during oocyte meiosis. Curr. Opin. Cell Biol. 23, 78- 84. (10.1016/j.ceb.2010.07.008) 20708397 PMC2994957 · DOI
  22. [22]Lampson MA, Black BE. 2017 Cellular and molecular mechanisms of centromere drive. Cold Spring Harb. Symp. Quant. Biol. 82, 249- 257. (10.1101/sqb.2017.82.034298) 29440567 PMC6041145 · DOI
  23. [23]Henikoff S, Ahmad K, Malik HS. 2001 The centromere paradox: stable inheritance with rapidly evolving DNA. Science 293, 1098- 1102. (10.1126/science.1062939) 11498581 · DOI
  24. [24]Malik HS, Henikoff S. 2002 Conflict begets complexity: the evolution of centromeres. Curr. Opin. Genet. Dev. 12, 711- 718. (10.1016/S0959-437X(02)00351-9) 12433586 · DOI
  25. [25]Stewart NB, Ahmed-Braimah YH, Cerne DG, McAllister BF. 2019 Female meiotic drive preferentially segregates derived metacentric chromosomes in Drosophila. bioRxiv.
  26. [26]Gong N, Yang H, Zhang G, Landau BJ, Guo X. 2004 Chromosome inheritance in triploid Pacific oyster Crassostrea gigas Thunberg. Heredity 93, 408- 415. (10.1038/sj.hdy.6800517) 15254489 · DOI
  27. [27]LeMaire-Adkins R, Radke K, Hunt PA. 1997 Lack of checkpoint control at the metaphase/anaphase transition: a mechanism of meiotic nondisjunction in mammalian females. J. Cell Biol. 139, 1611- 1619. (10.1083/jcb.139.7.1611) 9412457 PMC2132649 · DOI
  28. [28]LeMaire-Adkins R, Hunt PA. 2000 Nonrandom segregation of the mouse univalent X chromosome: evidence of spindle-mediated meiotic drive. Genetics 156, 775- 783. (10.1093/genetics/156.2.775) 11014823 PMC1461275 · DOI
  29. [29]Cortes D, McNally K, Mains PE, McNally FJ. 2015 The asymmetry of female meiosis reduces the frequency of inheritance of unpaired chromosomes. Elife 2015, 1- 21. (10.7554/elife.06056.018) PMC4412107 25848744 · DOI
  30. [30]Iwata-otsubo A, Dawicki-mckenna JM, Akera T, Falk SJ, Black BE. 2017 Expanded satellite repeats amplify a discrete CENP-A nucleosome assembly site on chromosomes that drive in female meiosis. Curr. Biol. 27, 2365- 2373. (10.1016/j.cub.2017.06.069) 28756949 PMC5567862 · DOI
  31. [31]Fishman L, Kelly JK. 2015 Centromere-associated meiotic drive and female fitness variation in Mimulus guttatus. Evolution 69, 1208- 1218. (10.1111/evo.12661) 25873401 PMC5958614 · DOI
  32. [32]Buckler IV ES, Phelps-Durr TL, Buckler CSK, Dawe RK, Doebley JF, Holtsford TP. 1999 Meiotic drive of chromosomal knobs reshaped the maize genome. Genetics 153, 415- 426. (10.1093/genetics/153.1.415) 10471723 PMC1460728 · DOI · Paper page
  33. [33]Agulnik SI, Agulnik AI, Ruvinsky AO. 1990 Meiotic drive in female mice heterozygous for the HSR inserts on chromosome 1. Gen. Res. 55, 97- 100. (10.1017/s0016672300025325) 2164490 · DOI
  34. [34]Didion JP et al. 2015 A multi-megabase copy number gain causes maternal transmission ratio distortion on mouse chromosome 2. PLoS Genet. 11, 1- 29. (10.1371/journal.pgen.1004850) PMC4334553 25679959 · DOI
  35. [35]Wu G, Hao L, Han Z, Gao S, Latham KE, De Villena FPM, Sapienza C. 2005 Maternal transmission ratio distortion at the mouse Om locus results from meiotic drive at the second meiotic division. Genetics 170, 327- 334. (10.1534/genetics.104.039479) 15744049 PMC1449735 · DOI
  36. [36]Drpic D et al. 2018 Chromosome segregation is biased by kinetochore size. Curr. Biol. 28, 1344- 1356. (10.1016/j.cub.2018.03.023) 29706521 PMC5954971 · DOI
  37. [37]Chmátal L, Gabriel SI, Mitsainas GP, Martínez-Vargas J, Ventura J, Searle JB, Schultz R, Lampson M. 2014 Centromere strength provides the cell biological basis for meiotic drive and karyotype evolution in mice. Curr. Biol. 24, 2295- 2300. (10.1016/j.cub.2014.08.017) 25242031 PMC4189972 · DOI · Paper page
  38. [38]Akera T, Trimm E, Lampson MA. 2019 Molecular and evolutionary strategies of meiotic cheating by selfish centromeres. Cell 178, 1132- 1144. (10.1016/j.cell.2019.07.001) 31402175 PMC6731994 · DOI
  39. [39]Wu T, Lane SIR, Morgan SL, Jones KT. 2018 Spindle tubulin and MTOC asymmetries may explain meiotic drive in oocytes. Nat. Commun. 9, 2952. (10.1038/s41467-018-05338-7) 30054463 PMC6063951 · DOI
  40. [40]Akera T, Chmátal L, Trimm E, Yang K, Aonbangkhen C, Chenoweth DM, Janke C, Schultz RM, Lampson MA. 2017 Spindle asymmetry drives non-Mendelian chromosome segregation. Science 358, 668- 672. (10.1126/science.aan0092) 29097549 PMC5906099 · DOI
  41. [41]Halet G, Carroll J. 2007 Rac activity is polarized and regulates meiotic spindle stability and anchoring in mammalian oocytes. Dev. Cell 12, 309- 317. (10.1016/j.devcel.2006.12.010) 17276347 · DOI
  42. [42]Deng M, Suraneni P, Schultz RM, Li R. 2007 The Ran GTPase mediates chromatin signaling to control cortical polarity during polar body extrusion in mouse oocytes. Dev. Cell 12, 301- 308. (10.1016/j.devcel.2006.11.008) 17276346 · DOI
  43. [43]Li R, Albertini DF. 2013 The road to maturation: somatic cell interaction and self-organization of the mammalian oocyte. Nat. Rev. Mol. Cell Biol. 14, 141- 152. (10.1038/nrm3531) 23429793 · DOI
  44. [44]Dehapiot B, Halet G. 2013 Ran GTPase promotes oocyte polarization by regulating ERM (Ezrin/Radixin/Moesin) inactivation. Cell Cycle 12, 1672- 1678. (10.4161/cc.24901) 23656777 PMC3713125 · DOI
  45. [45]Dehapiot B, Carrière V, Carroll J, Halet G. 2013 Polarized Cdc42 activation promotes polar body protrusion and asymmetric division in mouse oocytes. Dev. Biol. 377, 202- 212. (10.1016/j.ydbio.2013.01.029) 23384564 PMC3690527 · DOI
  46. [46]Carmena M, Wheelock M, Funabiki H, Earnshaw WC. 2012 The chromosomal passenger complex (CPC): from easy rider to the godfather of mitosis. Nat. Rev. Mol. Cell Biol. 13, 789- 803. (10.1038/nrm3474) 23175282 PMC3729939 · DOI
  47. [47]Godek KM, Kabeche L, Compton DA. 2015 Regulation of kinetochore–microtubule attachments through homeostatic control during mitosis. Nat. Rev. Mol. Cell Biol. 16, 57- 64. (10.1038/nrm3916) 25466864 PMC4568440 · DOI
  48. [48]Lampson MA, Grishchuk EL. 2017 Mechanisms to avoid and correct erroneous kinetochore-microtubule attachments. Biology 6, 1. (10.3390/biology6010001) 28067761 PMC5371994 · DOI
  49. [49]Verzijlbergen KF et al. 2014 Shugoshin biases chromosomes for biorientation through condensin recruitment to the pericentromere. Elife 2014, 1- 26. (10.7554/elife.01374.033) PMC3910079 24497542 · DOI
  50. [50]Marston AL. 2015 Shugoshins: tension-sensitive pericentromeric adaptors safeguarding chromosome segregation. Mol. Cell Biol. 35, 634- 648. (10.1128/MCB.01176-14) 25452306 PMC4301718 · DOI
  51. [51]Peris L et al. 2009 Motor-dependent microtubule disassembly driven by tubulin tyrosination. J. Cell Biol. 185, 1159- 1166. (10.1083/jcb.200902142) 19564401 PMC2712961 · DOI
  52. [52]Sirajuddin M, Rice LM, Vale RD. 2014 Regulation of microtubule motors by tubulin isotypes and posttranslational modifications. Nat. Cell Biol. 16, 335- 344. (10.1038/ncb2920) 24633327 PMC4117587 · DOI
  53. [53]Watanabe Y. 2012 Geometry and force behind kinetochore orientation: lessons from meiosis. Nat. Rev. Mol. Cell Biol. 13, 370- 382. (10.1038/nrm3349) 22588367 · DOI
  54. [54]Kawashima SA, Yamagishi Y, Honda T, Lshiguro KI, Watanabe Y. 2010 Phosphorylation of H2A by Bub1 prevents chromosomal instability through localizing shugoshin. Science 327, 172- 177. (10.1126/science.1180189) 19965387 · DOI
  55. [55]Houlard M, Godwin J, Metson J, Lee J, Hirano T, Nasmyth K. 2015 Condensin confers the longitudinal rigidity of chromosomes. Nat. Cell Biol. 17, 771- 781. (10.1038/ncb3167) 25961503 PMC5207317 · DOI
  56. [57]Finseth FR, Nelson TC, Fishman L. 2020 Selfish chromosomal drive shapes recent centromeric histone evolution in monkeyflowers. bioRxiv. (10.1101/2020.09.11.293597) · DOI
  57. [58]Kumon T et al. 2020 Centromere drive and suppression by parallel pathways for recruiting microtubule destabilizers. bioRxiv. (10.1101/2020.11.26.400515) · DOI
  58. [59]Ainsztein AM, Kandels-Lewis SE, Mackay AM, Earnshaw WC. 1998 INCENP centromere and spindle targeting: identification of essential conserved motifs and involvement of heterochromatin protein HP1. J. Cell Biol. 143, 1763- 1774. (10.1083/jcb.143.7.1763) 9864353 PMC2175214 · DOI
  59. [60]Tsukahara T, Tanno Y, Watanabe Y. 2010 Phosphorylation of the CPC by Cdk1 promotes chromosome bi-orientation. Nature 467, 719- 723. (10.1038/nature09390) 20739936 · DOI
  60. [61]Abe Y, Sako K, Takagaki K, Hirayama Y, Uchida KSK, Herman JA, Deluca J, Hirota T. 2016 HP1-assisted Aurora B kinase activity prevents chromosome segregation errors. Dev. Cell 36, 487- 497. (10.1016/j.devcel.2016.02.008) 26954544 PMC4949072 · DOI
  61. [62]Rhoades MM. 1942 Preferential segregation in Maize. Genetics 27, 395- 407. (10.1093/genetics/27.4.395) 17247049 PMC1209167 · DOI
  62. [63]Longley AE. 1945 Abnormal segregation during megasporogenesis in maize. Genetics 30, 100- 113. (10.1093/genetics/30.1.100) 17247142 PMC1209271 · DOI
  63. [64]Serbes EI, Palovaara J, Groß-Hardt R. 2019 Development and function of the flowering plant female gametophyte. Curr. Topics Dev. Biol. 131, 401- 434. (10.1016/bs.ctdb.2018.11.016) 30612625 · DOI
  64. [65]Swentowsky KW et al. 2020 Distinct kinesin motors drive two types of maize neocentromeres. Genes Dev. 34, 1239- 1251. (10.1101/gad.340679.120) 32820038 PMC7462060 · DOI
  65. [66]Rhoades MM, Vilkomerson H. 1942 On the anaphase movement of chromosomes. Proc. Natl Acad. Sci. USA 28, 433- 436. (10.1073/pnas.28.10.433) 16588574 PMC1078510 · DOI
  66. [67]Dawe RK, Hiatt EN. 2004 Plant neocentromeres: fast, focused, and driven. Chromosom. Res. 12, 655- 669. (10.1023/B:CHRO.0000036607.74671.db) 15289670 · DOI
  67. [68]Rhoades M. 1952 Heterosis. In Preferential segregation in maize (ed. JW Gowen), pp. 66–80. Ames, IA: Iowa State College Press. PMC1209167 17247049
  68. [69]Yu HG, Hiatt EN, Chan A, Sweeney M, Dawe RK. 1997 Neocentromere-mediated chromosome movement in maize. J. Cell Biol. 139, 831- 840. (10.1083/jcb.139.4.831) 9362502 PMC2139958 · DOI
  69. [70]Dawe RK et al. 2018 A kinesin-14 motor activates neocentromeres to promote meiotic drive in maize. Cell 173, 839- 850. (10.1016/j.cell.2018.03.009) 29628142 · DOI
  70. [71]Hunter AW, Caplow M, Coy DL, Hancock WO, Diez S, Wordeman L, Howard J. 2003 The kinesin-related protein MCAK is a microtubule depolymerase that forms an ATP-hydrolyzing complex at microtubule ends. Mol. Cell. 11, 445- 457. (10.1016/S1097-2765(03)00049-2) 12620232 PMC6468321 · DOI
  71. [72]Valente GT, Conte MA, Fantinatti BEA, Cabral-De-Mello DC, Carvalho RF, Vicari MR, Kocher TD, Martins C. 2014 Origin and evolution of B chromosomes in the cichlid fish astatotilapia latifasciata based on integrated genomic analyses. Mol. Biol. Evol. 31, 2061- 2072. (10.1093/molbev/msu148) 24770715 · DOI
  72. [73]Navarro-Domínguez B et al. 2017 Protein-coding genes in B chromosomes of the grasshopper Eyprepocnemis plorans. Sci. Rep. 7, 1- 12. (10.1038/s41598-016-0028-x) 28367986 PMC5377258 · DOI · Paper page
  73. [74]Makunin AI et al. 2018 Sequencing of supernumerary chromosomes of red fox and raccoon dog confirms a non-random gene acquisition by B chromosomes. Genes 9, 1- 14. (10.3390/genes9080405) PMC6116037 30103445 · DOI
  74. [75]Clark FE, Conte MA, Kocher TD. 2018 Genomic characterization of a B chromosome in Lake Malawi cichlid fishes. Genes 9, 610. (10.3390/genes9120610) 30563180 PMC6316868 · DOI
  75. [76]Zwick ME, Salstrom JL, Langley CH. 1999 Genetic variation in rates of nondisjunction: association of two naturally occuring polymorphisms in the chromokinesin nod with increased rates of nondisjunction in Drosophila melanogaster. Genetics 152, 1605- 1614. (10.1093/genetics/152.4.1605) 10430586 PMC1460721 · DOI
  76. [77]Didion JP et al. 2016 R2d2 drives selfish sweeps in the house mouse. Mol. Biol. Evol. 33, 1381- 1395. (10.1093/molbev/msw036) 26882987 PMC4868115 · DOI
  77. [78]Chmátal L, Schultz RM, Black BE, Lampson MA. 2017 Cell biology of cheating-transmission of centromeres and other selfish elements through asymmetric meiosis. Prog. Mol. Subcell Biol. 56, 377- 396. (10.1007/978-3-319-58592-5_16) 28840246 · DOI
  78. [79]Ruvinsky A. 1995 Meiotic drive in female mice: an essay. Mamm. Genome 6, 315- 320. (10.1007/BF00364793) 7626881 · DOI
  79. [80]Chaigne A, Verlhac MH, Terret ME. 2012 Spindle positioning in mammalian oocytes. Exp. Cell Res. 318, 1442- 1447. (10.1016/j.yexcr.2012.02.019) 22406266 · DOI
  80. [81]Cattanach BM. 1962 XO mice. Genet. Res. 3, 487- 490. (10.1017/S0016672300003335) · DOI
  81. [82]Kaufman MH. 1972 Non-random segregation during mammalian oogenesis. Nature 238, 465- 466. (10.1038/238465a0) 4561859 · DOI
  82. [83]Luthardt FW. 1976 Cytogenetic analysis of oocytes and early preimplantation embryos from XO mice. Dev. Biol. 54, 73- 81. (10.1016/0012-1606(76)90287-6) 1033885 · DOI
  83. [84]Goodwin EB, Ellis RE. 2002 Turning clustering loops: sex determination in Caenorhabditis elegans. Curr. Biol. 12, R111- R120. (10.1016/S0960-9822(02)00675-9) 11839294 · DOI
  84. [85]Goldstein P. 1984 Triplo-X hermaphrodite of Caenorhabditis elegans: pachytene karyotype analysis, synaptonemal complexes, and pairing mechanisms. Can. J. Genet. Cytol. 26, 13- 17. (10.1139/g84-003) · DOI
  85. [86]Vargas E, McNally K, Friedman JA, Cortes DB, Wang DY, Korf IF, Mcnally FJ. 2017 Autosomal trisomy and triploidy are corrected during female meiosis in caenorhabditis elegans. Genetics 207, 911- 922. (10.1534/genetics.117.300259) 28882988 PMC5676225 · DOI
  86. [87]Henery CC, Kaufman MH. 1993 The cleavage rate of digynic triploid mouse embryos during the preimplantation period. Mol. Reprod. Dev. 34, 272- 279. (10.1002/mrd.1080340307) 8471249 · DOI
  87. [88]Endo A, Watanabe T. 1989 A case of X-trisomy in the mouse. Cytogenet. Cell Genet. 52, 98- 99. (10.1159/000132852) 2612224 · DOI
  88. [89]Jones RN, Viegas W, Houben A. 2008 A century of B chromosomes in plants: so what? Ann. Bot. 101, 767- 775. (10.1093/aob/mcm167) 17704238 PMC2710218 · DOI
  89. [90]Houben A. 2017 B chromosomes – a matter of chromosome drive. Front. Plant Sci. 8, 1- 6. (10.3389/fpls.2017.00210) 28261259 PMC5309253 · DOI
  90. [91]Camacho JPM. 2005 The evolution of the genome, pp. 223- 286. London, UK: Academic Press.
  91. [92]Jones RN. 2018 Transmission and drive involving parasitic B chromosomes. Genes 9, 388. (10.3390/genes9080388) 30065230 PMC6115934 · DOI
  92. [93]Ruban A, Schmutzer T, Scholz U, Houben A. 2017 How next-generation sequencing has aided our understanding of the sequence composition and origin of B chromosomes. Genes (Basel) 8, 1- 14. (10.3390/genes8110294) PMC5704207 29068386 · DOI
  93. [94]Camacho Houben A, Banaei-Moghaddam AM, Klemme S, Timmis JN. 2014 Evolution and biology of supernumerary B chromosomes. Cell. Mol. Life Sci. 71, 467- 478. (10.1007/s00018-013-1437-7) 23912901 PMC11113615 · DOI
  94. [95]Hewitt G. 1973 Variable transmission rates of a B-chromosome in Myrmeleotettix maculatus (Thunb.) (Acrididae: Orthoptera). Chromosoma 40, 83- 106. (10.1007/BF00319837) 4682087 · DOI
  95. [96]Hewitt GM. 1976 Meiotic drive for B-chromosomes in the primary oocytes of Myrmekotettix maculatus (Orthoptera: Acrididae). Chromosoma 56, 381- 391. (10.1007/BF00292957) 949923 · DOI
  96. [97]Kayano H. 1957 Cytogenetic studies in Lilium callosum: III. Preferential segregation of a supernumerary chromosome in EMCs. Proc. Jap. Acad. 33, 553- 558. (10.2183/pjab1945.33.553) · DOI
  97. [98]Vujošević M, Rajičić M, Blagojević J. 2018 B chromosomes in populations of mammals revisited. Genes (Basel). 9, 487. 30304868 PMC6210394
  98. [99]Molina WF, Martinez PA, Bertollo LAC, Bidau CJ. 2014 Preferential accumulation of sex and Bs chromosomes in biarmed karyotypes by meiotic drive and rates of chromosomal changes in fishes. An. Acad. Bras. Cienc. 86, 1801- 1812. (10.1590/0001-3765201420130489) 25590717 · DOI
  99. [100]Clark FE, Conte MA, Ferreira-Bravo IA, Poletto AB, Martins C, Kocher TD. 2017 Dynamic sequence evolution of a sex-associated b chromosome in lake Malawi cichlid fish. J. Hered. 108, 53- 62. (10.1093/jhered/esw059) 27630131 · DOI
  100. [101]Habig M, Kema GHJ, Stukenbrock EH. 2018 Meiotic drive of female-inherited supernumerary chromosomes in a pathogenic fungus. Elife 7, 1- 20. PMC6331196 30543518
  101. [102]Makunin AI, Dementyeva PV, Graphodatsky AS, Volobouev VT, Kukekova AV, Trifonov VA. 2014 Genes on B chromosomes of vertebrates. Mol. Cytogenet. 7, 1- 10. (10.1186/s13039-014-0099-y) 25538793 PMC4274688 · DOI
  102. [103]Makunin AI et al. 2016 Contrasting origin of B chromosomes in two cervids (Siberian roe deer and grey brocket deer) unravelled by chromosome-specific DNA sequencing. BMC Genomics 17, 1- 14. (10.1186/s12864-016-2933-6) 27516089 PMC4982142 · DOI
  103. [104]Ahmad S, Martins C. 2019 The modern view of B chromosomes under the impact of high scale omics analyses. Cells 8, 156. (10.3390/cells8020156) 30781835 PMC6406668 · DOI
  104. [105]Kichigin IG et al. 2019 First report on B chromosome content in a reptilian species: the case of Anolis carolinensis. Mol. Genet. Genomics 294, 13- 21. (10.1007/s00438-018-1483-9) 30146671 · DOI
  105. [106]Ahmad SF et al. 2020 B chromosomes of multiple species have intense evolutionary dynamics and accumulated genes related to important biological processes. BMC Genomics 21, 1- 25. (10.1186/s12864-019-6419-1) PMC7509943 32967626 · DOI
  106. [107]Benetta ED, Akbari OS, Ferree PM. 2019 Sequence expression of supernumerary B chromosomes: function or fluff? Genes (Basel) 10, 123. 30744010 PMC6409846
  107. [108]Pigozzi MI, Solari AJ. 1998 Germ cell restriction and regular transmission of an accessory chromosome that mimics a sex body in the zebra finch, Taeniopygia guttata. Chromosom. Res. 6, 105- 113. (10.1023/A:1009234912307) 9543013 · DOI
  108. [109]Pigozzi MI, Solari AJ. 2005 The germ-line-restricted chromosome in the zebra finch: recombination in females and elimination in males. Chromosoma 114, 403- 409. (10.1007/s00412-005-0025-5) 16215738 · DOI
  109. [110]Torgasheva AA et al. 2019 Germline-restricted chromosome (GRC) is widespread among songbirds. Proc. Natl Acad. Sci. USA 116, 11 845- 11 850. 31036668 PMC6575587
  110. [111]Malinovskaya LP et al. 2020 Germline-restricted chromosome (GRC) in the sand martin and the pale martin (Hirundinidae, Aves): synapsis, recombination and copy number variation. Sci. Rep. 10, 1- 10. (10.1038/s41598-020-58032-4) 31974427 PMC6978364 · DOI
  111. [112]Smith JJ, Timoshevskiy VA, Saraceno C. 2021 Programmed DNA elimination in vertebrates. Annu. Rev. Anim. Biosci. 9, 173- 201. (10.1146/annurev-animal-061220-023220) 32986476 PMC8715500 · DOI
  112. [113]Schoenmakers S, Wassenaar E, Laven JSE, Grootegoed JA, Baarends WM. 2010 Meiotic silencing and fragmentation of the male germline restricted chromosome in zebra finch. Chromosoma 119, 311- 324. (10.1007/s00412-010-0258-9) 20162291 PMC2875885 · DOI
  113. [114]Kinsella CM et al. 2019 Programmed DNA elimination of germline development genes in songbirds. Nat. Commun. 10, 1- 10. (10.1038/s41467-019-13427-4) 31784533 PMC6884545 · DOI

Authors
Clark, F. E., & Akera, T.
Affiliations
National Institutes of Health (US)
Corresponding author
  • Clark, Frances E.
  • Akera, Takashi
ORCID
Venue
Open Biology
Publisher
The Royal Society
Published
2021-09-01
Volume
11
Issue
9
Pages
210074-210074
ISSN
2046-2441 (ISSN-L)
DOI
10.1098/rsob.210074
PMC
PMC8437031
OpenAlex
W3197355236
Cited by
58
References
115
Citations by year
2026: 13 · 2025: 14 · 2024: 10 · 2023: 8 · 2022: 13
FWCI
0.74
Type
journal article
Language
en
Open access
Licence
Locations
  • Open Biology (publishedVersion, cc-by)
  • Europe PMC (PubMed Central) (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Funders
National Heart, Lung, and Blood Institute (1ZIAHL006249-01)
Topics
  • Life Sciences › Agricultural and Biological Sciences › Plant Science › Chromosomal and Genetic Variations
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Microtubule and mitosis dynamics
Keywords
selfish genetic elements, chromosome segregation, Mendelian inheritance, comparative genetics, meiosis, transposable elements, comparative genomics
MeSH terms
Animals, Centromere, Female, Meiosis, Plants, Chromosome Segregation

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review