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A method of breaking down the body weights of living persons into terms of extracellular fluid, cell mass and fat, and some applications of it to physiology and medicine
Abstract
The volume of the extracellular fluid has been measured by estimating the thiocyanate ‘space' and correcting for the penetration of thiocyanate into the erythrocytes. The total body water has been determined by measuring the volume of the body into which a known amount of urea distributed itself and the fat has been determined by difference after making an allowance for minerals. The accuracy of the method has been tested in a number of ways. The composition of the bodies of twenty-one normal and obese men and women have been investigated. A person of standard weight for height contains 16 to 17% of fat. The bodies of ten undernourished Germans recently repatriated from camps for prisoners of war in Russia have been analyzed before and after rehabilitation and the effects have thereby been demonstrated. This method should help to solve a number of physiological, nutritional and medical problems; some of its applications have been indicated and discussed.
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Cited by
The Gross Composition of the Body
SIRI, W. E. (1956) · Advances in Biological and Medical Physics · doi:10.1016/b978-1-4832-3110-5.50011-x · Cited by 1,765
Determination of total adipose tissue and body fat in women by computed tomography, 40K, and tritium
Sjostrom, L., Kvist, H., Cederblad, A., & Tylen, U. (1986) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1986.250.6.e736 · Cited by 368
Body composition in chronic undernutrition
Barac-Nieto, M., Spurr, G., Lotero, H., & Maksud, M. (1978) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/31.1.23 · Cited by 162
Metadata
- Authors
- McCance, R. A., & Widdowson, E. M.
- Venue
- Proceedings of the Royal Society of London. Series B - Biological Sciences
- Publisher
- The Royal Society
- Published
- 1951-02-15
- Volume
- 138
- Issue
- 890
- Pages
- 115-130
- ISSN
- 0080-4649 (ISSN-L)
- 2053-9193
- OpenAlex
- W1966710038
- Cited by
- 202
- References
- 0
- FWCI
- 36.94
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: A method of breaking down the body weights of living persons into terms of extracellular fluid, cell mass and fat, and some applications of it to physiology and medicine. https://app.cochat.ai/papers/10.1098/rspb.1951.0010
- The paper
- McCance, R. A., & Widdowson, E. M. (1951). A method of breaking down the body weights of living persons into terms of extracellular fluid, cell mass and fat, and some applications of it to physiology and medicine. Proceedings of the Royal Society of London. Series B - Biological Sciences. https://doi.org/10.1098/rspb.1951.0010
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
